Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5639-5647

  Bhaskar Kumar, T ^a,b   Sumanth, Ch ^a   Vaishaly, S ^a   Srinivasa Rao, M ^a   Chandra Sekhar, K B ^b   Meda, Chandana Lakshmi T ^c   Kandale, Ajit ^c   Rambabu, D ^c   Rama Krishna, G ^d   Malla Reddy, C ^d   Shiva Kumar, K ^c   Parsa, Kishore V L ^c   Pal, Manojit ^c  

^a DR REDDY'S LABORATORIES LTD   (India)

^b JNT University Anantapur   (India)

^c INSTITUTE OF LIFE SCIENCES   (India)

^d INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA   (India)

Author keywords

Coupling; MCR; Palladium; PDE4; Pyrrole

Indexed keywords

PALLADIUM; PDE4B PROTEIN; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CRYSTAL STRUCTURE; DRUG SCREENING; DRUG SYNTHESIS; HECK REACTION; IN VITRO STUDY; MOLECULAR DOCKING; ONE POT SYNTHESIS;

ANIMALS; CATALYSIS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; MODELS, MOLECULAR; PALLADIUM; PHOSPHODIESTERASE 4 INHIBITORS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865153280     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.06.100     Document Type: Article

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