An amplified promoter system for targeted expression of calcium indicator proteins in the cerebellar cortex

Frontiers in Neural Circuits

Volumn , Issue JULY 2012, 2012, Pages

  Kuhn, Bernd ^a,b   Ozden, Ilker ^a,c   Lampi, Yulia ^a   Hasan, Mazahir T ^d,e   Wang, Samuel S H ^a  

^a PRINCETON UNIVERSITY   (United States)

^b OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

^c Brown University   (United States)

^d MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

AAV; Cerebellum; Crus; FCIP; GECI; In vivo; TET; Two photon

Indexed keywords

BIOLOGICAL MARKER; CALCIUM INDICATOR PROTEIN; PARVOVIRUS VECTOR; SYNAPSIN; TETRACYCLINE TRANSACTIVATOR PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CEREBELLUM CORTEX; CONTROLLED STUDY; CYTOTOXICITY; GENE AMPLIFICATION; INTERNEURON; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TARGETING; PURKINJE CELL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; WAKEFULNESS;

EID: 84865150058     PISSN: 16625110     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncir.2012.00049     Document Type: Article

References (43)

1. Brown, I. E., and Bower, J. M. (2001). Congruence of mossy fiber and climbing fiber tactile projections in the lateral hemispheres of the rat cerebellum. J. Comp. Neurol. 429, 59-70.
2. Burger, C., Nguyen, F. N., Deng, J., and Mandel, R. J. (2005). Systemic mannitol-induced hyperosmolality amplifies rAAV2-mediated striatal transduction to a greater extent than local co-infusion. Mol. Ther. 11, 327-331.
3. Collin, T., Chat, M., Lucas, M. G., Moreno, H., Racay, P., Schwaller, B., Marty, A., and Llano, I. (2005). Developmental changes in parval- bumin regulate presynaptic Ca2+ signaling. J. Neurosci. 25, 96-107.
4. Crook, J., Hendrickson, A., and Robinson, F. R. (2006). Co-localization of glycine and GABA immunoreactivity in interneurons in Macaca monkey cerebellar cortex. Neuroscience 141, 1951-1959.
5. Flusberg, B. A., Nimmerjahn, A., Cocker, E. D., Mukamel, E. A., Barretto, R. P., Ko, T. H., Burns, L. D., Jung, J. C., and Schnitzer, M. J. (2008). High-speed, miniaturized fluorescence microscopy in freely moving mice. Nat. Methods 5, 935-938.
6. Franconville, R., Revet, G., Astorga, G., Schwaller, B., and Llano, I. (2011). Somatic calcium level reports inte-grated spiking activity of cerebellar interneurons in vitro and in vivo. J. Neurophysiol. 106, 1793-1805.
7. Hasan, M. T., Friedrich, R. W., Euler, T., Larkum, M. E., Giese, G., Both, M., Duebel, J., Waters, J., Bujard, H., Griesbeck, O., Tsien, R. Y., Nagai, T., Miyawaki, A., and Denk, W. (2004). Functional fluorescent Ca(2+) indicator proteins in trans-genic mice under TET control. PLoS Biol. 2:e163. doi: 10.1371/ journal.pbio.0020163
8. Hendel, T., Mank, M., Schnell, B., Griesbeck, O., Borst, A., and Reiff, D. F. (2008). Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activ-ity and calcium in vivo and in vitro. J. Neurosci. 28, 7399-7411.
9. Hoogland, T. M., Kuhn, B., Göbel, W., Huang, W., Nakai, J., Helmchen, F., Flint, J., and Wang, S.S.-H. (2009). Radially expanding transglial cal-cium waves in the intact cerebellum. Proc. Natl. Acad. Sci. U.S.A. 106, 3496-3501.
10. Huber, D., Gutnisky, D. A., Peron, S., O'Connor, D. H., Wiegert, J. S., Tian, L., Oertner, T. G., Looger, L. L., and Svoboda, K. (2012). Multiple dynamic representations in the motor cortex during sen-sorimotor learning. Nature 484, 473-478.
11. Hyvarinen, A., and Oja, E. (2000). Independent component analysis: algorithms and applications. Neural Netw. 13, 411-430.
12. Kosaka, T., Kosaka, K., Nakayama, T., Hunziker, W., and Heizmann, C. W. (1993). Axons and axon ter-minals of cerebellar Purkinje cells and basket cells have higher lev-els of parvalbumin immunoreac-tivity than somata and dendrites: quantitative analysis by immuno-gold labeling. Exp. Brain Res. 93, 483-491.
13. Kuhn, B., Hoogland, T. M., and Wang, S.S.-H. (2011). Injection of recombinant adenovirus for delivery of genetically encoded calcium indicators into astrocytes of the cerebellar cortex. Cold Spring Harb. Protoc. 2011, 1217-1223.
14. Laine, J., and Axelrad, H. (1994). The candelabrum cell: a new interneuron in the cerebellar cortex. J. Comp. Neurol. 339, 159-173.
15. Laine, J., and Axelrad, H. (1996). Morphology of the Golgi- impregnated Lugaro cell in the rat cerebellar cortex: a reappraisal with a description of its axon. J. Comp. Neurol. 375, 618-640.
16. Laine, J., and Axelrad, H. (2002). Extending the cerebellar Lugaro cell class. Neuroscience 115, 363-374.
17. Looger, L. L., and Griesbeck, O. (2011). Genetically encoded neural activ-ity indicators. Curr. Opin. Neurobiol. 22, 18-23.
18. Mukamel, E. A., Nimmerjahn, A., and Schnitzer, M. J. (2009). Automated analysis of cellular signals from large-scale calcium imaging data. Neuron 63, 747-760.
19. Nathanson, J. L., Yanagawa, Y., Obata, K., and Callaway, E. M. (2009). Preferentiallabelingofinhibitory and excitatorycorticalneurons byendogenoustropismofadeno- associatedvirusandlentivirus vectors. Neuroscience 161, 441-450.
20. Nimmerjahn, A., Mukamel, E. A., and Schnitzer, M. J. (2009).Motor behavioractivatesBergmannglial networks. Neuron 62, 400-412.
21. O'Connor, D. H., Huber, D., and Svoboda, K. (2009).Reverseengi- neeringthemousebrain. Nature 461, 923-929.
22. Ozden, I., Lee, H. M., Sullivan, M. R., and Wang, S.S. -H.(2008). Identificationandclustering of eventpatternsfrom in vivo multiphotonopticalrecord- ingsofneuronalensembles. J. Neurophysiol. 100, 495-503.
23. Ozden, I., Sullivan, M. R., Lee, H. M., and Wang, S.S.-H.(2009). Reliablecodingemergesfrom coactivationofclimbingfibers inmicrobandsofcerebellar Purkinjeneurons. J. Neurosci. 29, 10463-10473.
24. Palay, S. L., and Chan-Palay, V.(1974). CerebellarCortex:Cytologyand Organization. Berlin,Heidelberg, NewYork:Springer.
25. Palmer, A. E., Giacomello, M., Kortemme, T., Hires, S. A., Lev-Ram, V., Baker, D., and Tsien, R. Y. (2006).Ca(2+)indicatorsbased oncomputationallyredesigned calmodulin-peptidepairs. Chem. Biol. 13, 521-530.
26. Patterson, G. H., Knobel, S. M., Sharif, W. D., Kain, S. R., and Piston, D. W.(1997).Useof the greenfluorescentprotein and itsmutantsinquantitative fluorescencemicroscopy. Biophys.J. 73, 2782-2790.
27. Pologruto, T. A., Sabatini, B. L., and Svoboda, K. (2003).ScanImage: flexiblesoftwareforoperatinglaser scanningmicroscopes. Biomed. Eng.Online 2, 13.
28. Sala, F., and Hernández-Cruz, A. (1990). Calciumdiffusionmodeling inasphericalneuron.Relevanceof bufferingproperties. Biophys.J. 57, 313-324.
29. Schmidt, H.(2012).Threefunc- tionalfacetsofcalbindinD-28k. Front.Mol.Neurosci. 5:25. doi: 10.3389/fnmol.2012.00025
30. Schmidt, H., Stiefel, K. M., Racay, P., Schwaller, B., and Eilers, J. (2003). Mutationalanalysisofdendritic Ca2+kineticsinrodentPurkinje cells:roleofparvalbuminandcal- bindinD28k. J. Physiol. 551, 13-32.
31. Schultz, S. R., Kitamura, K., Post-Uiterweer, A., Krupic, J., and Häusser, M. (2009).Spatialpattern codingofsensoryinformation byclimbingfiber-evokedcalcium signalsinnetworksofneighboring cerebellarPurkinjecells. J. Neurosci. 29, 8005-8015.
32. Shevtsova, Z., Malik, J. M., Michel, U., Bahr, M., and Kugler, S. (2005). Promotersandserotypes:targeting of adeno-associatedvirusvectorsfor gene transferintheratcentralner- voussystem in vitro and in vivo. Exp.Physiol. 90, 53-59.
33. Simat, M., Parpan, F., and Fritschy, J. M. (2007).Heterogeneityofglycin- ergicandGABAergicinterneurons in thegranulecelllayerofmouse cerebellum. J. Comp.Neurol. 500, 71-83.
34. Sturrock, R. R. (1989).Changesinneuronnumberinthecerebellarcortex of theageingmouse. J. Hirnforsch. 30, 499-503.
35. Sullivan, M. R., Nimmerjahn, A., Sarkisov, D. V., Helmchen, F., and Wang, S.S. -H.(2005). In vivo calciumimagingofcircuitactivity incerebellarcortex. J. Neurophysiol. 94, 1636-1644.
36. Sun, X. R., Lampi, Y., Friling, T., Kuhn, B., Schneider, E., Lin, S.S., and Wang, S.S. -H.(2011).Improved fluorescence-basedtrackingofneu- ronalactivityusingfasterandlower- affinityvariantsofG-CaMP. Soc. Neurosci.MeetingAbstr. 840.03.
37. Tenenbaum, L., Chtarto, A., Lehtonen, E., Velu, T., Brotchi, J., and Levivier, M. (2004).RecombinantAAV- mediatedgenedeliverytothe centralnervoussystem. J.Gene Med. 6(Suppl.1),S212-S222.
38. Thorne, R. G., and Nicholson, C. (2006). In vivo diffusionanalysis withquantumdotsanddextrans predictsthewidthofbrainextra- cellularspace. Proc.Natl.Acad.Sci. U.S.A. 103, 5567-5572.
39. Tian, L., Akerboom, J., Schreiter, E. R., and Looger, L. L. (2012).Neural activityimagingwithgenetically encodedcalciumindicators. Prog. BrainRes. 196, 79-94.
40. Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., Mckinney, S. A., Schreiter, E. R., Bargmann, C. I., Jayaraman, V., Svoboda, K., and Looger, L. L. (2009).Imagingneuralactivity inworms,fliesandmicewith improvedGCaMPcalciumindicators. Nat.Methods 6, 875-881.
41. Wallace, D. J., Meyer Zum Alten Borgloh, S., Astori, S., Yang, Y., Bausen, M., Kugler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N., Denk, W., and Hasan, M. T. (2008).Single-spikedetection in vitro and in vivo withagenetic Ca(2+)sensor. Nat.Methods 5, 797-804.
42. Yamada, Y., Michikawa, T., Hashimoto, M., Horikawa, K., Nagai, T., Miyawaki, A., Häusser, M., and Mikoshiba, K. (2011).Quantitative comparisonofgeneticallyencoded Ca(2+)indicatorsincorticalpyra- midalcellsandcerebellarpurkinje cells. Front.Cell.Neurosci. 5:18. doi: 10.3389/fncel.2011.00018
43. Zariwala, H. A., Borghuis, B. G., Hoogland, T. M., Madisen, L., Tian, L., DeZeeuw, C. I., Zeng, H., Looger, L. L., Svoboda, K., and Chen, T. W.(2012). ACre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo. J. Neurosci. 32, 3131-3141.