Ex vivo gene delivery to hepatocytes: Techniques, challenges, and underlying mechanisms

Annals of Biomedical Engineering

Volumn 40, Issue 9, 2012, Pages 1851-1861

  Gao, Shan ^a   Seker, Erkin ^b   Casali, Monica ^a   Wang, Fangjing ^a   Bale, Shyam Sundhar ^a   Price, Gavrielle M ^a   Yarmush, Martin L ^a,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b University of California   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

Hepatic function; Huh7.5.1; Lentiviruses; Non viral transfection; Primary rat hepatocytes; Transfection efficiency

Indexed keywords

HEPATIC FUNCTION; HUH7.5.1; LENTIVIRUSES; NONVIRAL; RAT HEPATOCYTES; TRANSFECTION EFFICIENCY;

BIOMEMS; CELL CULTURE; CELLS; EFFICIENCY; ELECTROMECHANICAL DEVICES; GENE TRANSFER; GENES; LIPOSOMES; RATS; UREA;

MOLECULAR BIOLOGY;

ALBUMINOID; FUGENE; GREEN FLUORESCENT PROTEIN; LIPID; LIPOFECTAMINE; UREA;

ANIMAL; ARTICLE; CELL STRAIN HEK293; FEMALE; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HUMAN; LENTIVIRINAE; LEWIS RAT; LIVER CELL; MAGNETISM; METABOLISM; METHODOLOGY; RAT; TUMOR CELL LINE;

ALBUMINS; ANIMALS; CELL LINE, TUMOR; FEMALE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HEPATOCYTES; HUMANS; LENTIVIRUS; LIPIDS; MAGNETIC PHENOMENA; RATS; RATS, INBRED LEW; TRANSFECTION; UREA;

EID: 84865150034     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-012-0555-y     Document Type: Article

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