Long-range effects of familial hypertrophic cardiomyopathy mutations E180G and D175N on the properties of tropomyosin

Biochemistry

Volumn 51, Issue 32, 2012, Pages 6413-6420

  Ly, Socheata ^a   Lehrer, Sherwin S ^a,b  

^a BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAMILIAL HYPERTROPHIC CARDIOMYOPATHIES; LONG RANGE EFFECTS; MOLECULAR BASIS; N-TERMINALS; RESIDUAL LEVELS; SINGLE-SITE MUTATIONS; THIN FILAMENTS; TROPOMYOSIN;

CALCIUM; PROTEINS;

PATHOLOGY;

ADENOSINE TRIPHOSPHATASE; ALPHA TROPOMYOSIN; CALCIUM;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIASTOLE; DISEASE SEVERITY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; GENE MUTATION; HEART MUSCLE CONTRACTILITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SARCOMERE; THIN FILAMENT;

ACTINS; ADENOSINE TRIPHOSPHATASES; AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM CHLORIDE; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; CATIONS, DIVALENT; HOT TEMPERATURE; HUMANS; MUTATION; PROTEIN STABILITY; PROTEIN UNFOLDING; RABBITS; RATS; RECOMBINANT PROTEINS; TROPOMYOSIN; TRYPSIN;

EID: 84865119925     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3006835     Document Type: Article

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