A Co(III) complex cleaving soluble oligomers of h-IAPP in the presence of polymeric aggregates of h-IAPP

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5689-5693

  Lee, Tae Yeon ^a   Chei, Woo Suk ^a   Ju, Heeyeon ^a   Lee, Mi Sook ^a   Lee, Jung Weon ^a   Suh, Junghun ^a  

^a Seoul National University   (South Korea)

Author keywords

Amyloid; Amyloid diseases; Diabetes; h IAPP; Peptide cleavage agent

Indexed keywords

AMYLIN; COBALT COMPLEX; OLIGOMER;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; PEPTIDE LIBRARY; POLYMERIZATION; PROTEIN CLEAVAGE;

AMYLOIDOSIS; APOPTOSIS; CELL LINE; CELL SURVIVAL; COBALT; COORDINATION COMPLEXES; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN-SECRETING CELLS; ISLET AMYLOID POLYPEPTIDE; SOLUBILITY;

EID: 84865118147     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.06.089     Document Type: Article

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