Cell-penetration by Co(III)cyclen-based peptide-cleaving catalysts selective for pathogenic proteins of amyloidoses

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 14, 2010, Pages 5248-5253

  Chei, Woo Suk ^a   Lee, Joo Won ^a   Kim, Jae Bum ^a   Suh, Junghun ^a  

^a Seoul National University   (South Korea)

Author keywords

Amyloidoses; Catalytic drug; Cell penetration; Co(III)cyclen; Peptide cleaving catalyst

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE DERIVATIVE; COBALT COMPLEX; CYCLOALKANE DERIVATIVE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CATALYST; CELL PERMEABILIZATION; CELL STRAIN HEK293; CELL VIABILITY; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; HUNTINGTON DISEASE LIKE SYNDROME; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PARKINSON DISEASE; STRUCTURE ACTIVITY RELATION;

AMYLOIDOSIS; ANIMALS; CATALYSIS; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; HUMANS; MICE; NIH 3T3 CELLS; ORGANOMETALLIC COMPOUNDS; PEPTIDES; PROTEINS;

ANIMALIA;

EID: 77955321370     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.05.047     Document Type: Article

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