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Volumn 9, Issue 73, 2012, Pages 1998-2010

Regulation of oscillation dynamics in biochemical systems with dual negative feedback loops

Author keywords

Feedback strength; Mathematical modelling; Nested negative feedback; Oscillations

Indexed keywords

BIFURCATION (MATHEMATICS); BIOCHEMISTRY; DYNAMICS; MATHEMATICAL MODELS; ROBUST CONTROL;

EID: 84865100690     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2012.0028     Document Type: Article
Times cited : (29)

References (56)
  • 1
    • 54249137797 scopus 로고    scopus 로고
    • Feedback loops shape cellular signals in space and time
    • doi:10.1126/science.1160617
    • Brandman, O. & Meyer, T. 2008 Feedback loops shape cellular signals in space and time. Science 322, 390-395. (doi:10.1126/science.1160617)
    • (2008) Science , vol.322 , pp. 390-395
    • Brandman, O.1    Meyer, T.2
  • 2
    • 0034676456 scopus 로고    scopus 로고
    • Feedback control of intercellular signalling in development
    • doi:10.1038/35042500
    • Freeman, M. 2000 Feedback control of intercellular signalling in development. Nature 408, 313-319. (doi:10.1038/35042500)
    • (2000) Nature , vol.408 , pp. 313-319
    • Freeman, M.1
  • 3
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • doi:10.1016/S0955-0674(02)00314-9
    • Ferrell Jr, J. E. 2002 Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr. Opin. Cell Biol. 14, 140-148. (doi:10.1016/S0955-0674(02)00314-9)
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 140-148
    • Ferrell Jr., J.E.1
  • 5
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • doi:10.1111/j.0105-2896.2006.00375.x
    • Hoffmann, A. & Baltimore, D. 2006 Circuitry of nuclear factor kappaB signaling. Immunol. Rev. 210, 171-186. (doi:10.1111/j.0105-2896.2006.00375.x)
    • (2006) Immunol. Rev. , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 7
    • 78449248996 scopus 로고    scopus 로고
    • Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network
    • Cirit, M., Wang, C. C. & Haugh, J. M. 2010 Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network. J. Biol. Chem. 285, 36 736-36 744.
    • (2010) J. Biol. Chem. , vol.285 , pp. 36736-36744
    • Cirit, M.1    Wang, C.C.2    Haugh, J.M.3
  • 9
    • 0035367217 scopus 로고    scopus 로고
    • Control of the threonine-synthesis pathway in Escherichia coli: A theoretical and experimental approach
    • doi:10.1042/0264-6021:3560433
    • Chassagnole, C., Fell, D. A., Rais, B., Kudla, B. & Mazat, J. P. 2001 Control of the threonine-synthesis pathway in Escherichia coli: a theoretical and experimental approach. Biochem. J. 356, 433-444. (doi:10.1042/0264-6021: 3560433)
    • (2001) Biochem. J. , vol.356 , pp. 433-444
    • Chassagnole, C.1    Fell, D.A.2    Rais, B.3    Kudla, B.4    Mazat, J.P.5
  • 10
    • 3242668172 scopus 로고    scopus 로고
    • The different roles of tryptophan transfer RNA in regulating trp operon expression in E. coli versus B. subtilis
    • doi:10.1016/j.tig.2004.06.007
    • Yanofsky, C. 2004 The different roles of tryptophan transfer RNA in regulating trp operon expression in E. coli versus B. subtilis. Trends. Genet. 20, 367-374. (doi:10.1016/j.tig.2004.06.007)
    • (2004) Trends. Genet. , vol.20 , pp. 367-374
    • Yanofsky, C.1
  • 11
    • 58149400559 scopus 로고    scopus 로고
    • On multiple regulatory mechanisms in the tryptophan operon system in Escherichia coli: In silico study of perturbation dynamics
    • Nguyen, L. K. & Kulasiri, D. 2008 On multiple regulatory mechanisms in the tryptophan operon system in Escherichia coli: in silico study of perturbation dynamics. In Silico. Biol. 8, 0037.
    • (2008) In Silico. Biol. , vol.8 , pp. 0037
    • Nguyen, L.K.1    Kulasiri, D.2
  • 12
    • 79952657402 scopus 로고    scopus 로고
    • Distinct noise-controlling roles of multiple negative feedback mechanisms in a prokaryotic operon system
    • doi:10.1049/iet-syb.2010.0020
    • Nguyen, L. K. & Kulasiri, D. 2010 Distinct noise-controlling roles of multiple negative feedback mechanisms in a prokaryotic operon system. IET Syst. Biol. 5, 145-156. (doi:10.1049/iet-syb.2010.0020)
    • (2010) IET Syst. Biol. , vol.5 , pp. 145-156
    • Nguyen, L.K.1    Kulasiri, D.2
  • 13
    • 0035852686 scopus 로고    scopus 로고
    • Dynamic regulation of the tryptophan operon: A modeling study and comparison with experimental data
    • doi:10.1073/pnas.98.4.1364
    • Santillan, M. & Mackey, M. C. 2001 Dynamic regulation of the tryptophan operon: a modeling study and comparison with experimental data. Proc. Natl Acad. Sci. USA 98, 1364-1369. (doi:10.1073/pnas.98.4.1364)
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1364-1369
    • Santillan, M.1    Mackey, M.C.2
  • 14
    • 0345700833 scopus 로고    scopus 로고
    • Building a cell cycle oscillator: Hysteresis and bistability in the activation of Cdc2
    • doi:10.1038/ncb954
    • Pomerening, J. R., Sontag, E. D. & Ferrell Jr, J. E. 2003 Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat. Cell Biol. 5, 346-351. (doi:10.1038/ncb954)
    • (2003) Nat. Cell Biol. , vol.5 , pp. 346-351
    • Pomerening, J.R.1    Sontag, E.D.2    Ferrell Jr., J.E.3
  • 15
    • 68949136612 scopus 로고    scopus 로고
    • Interlinking positive and negative feedback loops creates a tunable motif in gene regulatory networks
    • doi:10.1103/PhysRevE.80.011926
    • Tian, X. J., Zhang, X. P., Liu, F. & Wang, W. 2009 Interlinking positive and negative feedback loops creates a tunable motif in gene regulatory networks. Phys. Rev. E Stat. Nonlin. Soft. Matter. Phys. 80, 011926. (doi:10.1103/PhysRevE.80.011926)
    • (2009) Phys. Rev. E Stat. Nonlin. Soft. Matter. Phys. , vol.80 , pp. 011926
    • Tian, X.J.1    Zhang, X.P.2    Liu, F.3    Wang, W.4
  • 16
    • 46849090495 scopus 로고    scopus 로고
    • Robust, tunable biological oscillations from interlinked positive and negative feedback loops
    • doi:10.1126/science.1156951
    • Tsai, T. Y., Choi, Y. S., Ma, W., Pomerening, J. R., Tang, C. &Ferrell Jr, J. E. 2008 Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science 321, 126-129. (doi:10.1126/science.1156951)
    • (2008) Science , vol.321 , pp. 126-129
    • Tsai, T.Y.1    Choi, Y.S.2    Ma, W.3    Pomerening, J.R.4    Tang, C.5    Ferrell Jr., J.E.6
  • 17
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
    • Kolch, W. 2000 Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem. J. 351(Pt 2), 289-305.
    • (2000) Biochem. J. , vol.351 , Issue.PART 2 , pp. 289-305
    • Kolch, W.1
  • 18
    • 0013823048 scopus 로고
    • Oscillatory behavior in enzymatic control processes
    • doi:10.1016/0065-2571(65)90067-1
    • Goodwin, B. C. 1965 Oscillatory behavior in enzymatic control processes. Adv. Enzyme. Regul. 3, 425-438. (doi:10.1016/0065-2571(65)90067-1)
    • (1965) Adv. Enzyme. Regul. , vol.3 , pp. 425-438
    • Goodwin, B.C.1
  • 19
    • 0019974626 scopus 로고
    • Role of feedback inhibition in stabilizing the classical operon
    • doi:10.1016/0022-5193(82)90098-4
    • Bliss, R. D., Painter, P. R. & Marr, A. G. 1982 Role of feedback inhibition in stabilizing the classical operon. J. Theor. Biol. 97, 177-193. (doi:10.1016/0022-5193(82)90098-4)
    • (1982) J. Theor. Biol. , vol.97 , pp. 177-193
    • Bliss, R.D.1    Painter, P.R.2    Marr, A.G.3
  • 20
    • 0014319313 scopus 로고
    • Mathematics of cellular control processes. I. Negative feedback to one gene
    • doi:10.1016/0022-5193(68)90189-6
    • Griffith, J. S. 1968 Mathematics of cellular control processes. I. Negative feedback to one gene. J. Theor. Biol. 20, 202-208. (doi:10.1016/0022- 5193(68)90189-6)
    • (1968) J. Theor. Biol. , vol.20 , pp. 202-208
    • Griffith, J.S.1
  • 21
    • 0001051330 scopus 로고
    • The Poincare-Bendixson theorem for monotone cyclic feedback systems
    • Mallet-Paret, J. & Smith, H. L. 1990 The Poincare-Bendixson theorem for monotone cyclic feedback systems. J. Dyn. Differ. Equ. 2, 169-190.
    • (1990) J. Dyn. Differ. Equ. , vol.2 , pp. 169-190
    • Mallet-Paret, J.1    Smith, H.L.2
  • 22
    • 0019885814 scopus 로고
    • Reconsideration of the theory of oscillatory repression
    • doi:10.1016/0022-5193(81)90048-5
    • Painter, P. R. & Bliss, R. D. 1981 Reconsideration of the theory of oscillatory repression. J. Theor. Biol. 90, 293-298. (doi:10.1016/0022-5193(81) 90048-5)
    • (1981) J. Theor. Biol. , vol.90 , pp. 293-298
    • Painter, P.R.1    Bliss, R.D.2
  • 23
    • 0024280662 scopus 로고
    • Complex behaviour of the repressible operon
    • doi:10.1016/S0022-5193(88)80217-0
    • Sinha, S. & Ramaswamy, R. 1988 Complex behaviour of the repressible operon. J. Theor. Biol. 132, 307-318. (doi:10.1016/S0022-5193(88)80217-0)
    • (1988) J. Theor. Biol. , vol.132 , pp. 307-318
    • Sinha, S.1    Ramaswamy, R.2
  • 24
    • 0002275384 scopus 로고
    • The dynamics of feedback control circuits in biochemical pathways
    • Tyson, J. & Othmer, H. G. 1978 The dynamics of feedback control circuits in biochemical pathways. Prog. Theor. Biol. 5, 2-62.
    • (1978) Prog. Theor. Biol. , vol.5 , pp. 2-62
    • Tyson, J.1    Othmer, H.G.2
  • 26
    • 33646975343 scopus 로고    scopus 로고
    • Stochastic fluctuations in gene expression far from equilibrium: Omega expansion and linear noise approximation
    • doi:10.1063/1.1870874
    • Tao, Y., Jia, Y. & Dewey, T. G. 2005 Stochastic fluctuations in gene expression far from equilibrium: omega expansion and linear noise approximation. J. Chem. Phys. 122, 124108. (doi:10.1063/1.1870874)
    • (2005) J. Chem. Phys. , vol.122 , pp. 124108
    • Tao, Y.1    Jia, Y.2    Dewey, T.G.3
  • 28
    • 0002501173 scopus 로고    scopus 로고
    • Chaos in high-dimensional neural and gene networks
    • doi:10.1016/0167-2789(96)00086-3
    • Mestl, T., Lemay, C. & Glass, L. 1996 Chaos in high-dimensional neural and gene networks. Phys. D Nonlinear Phenom. 98, 33-52. (doi:10.1016/0167-2789(96)00086-3)
    • (1996) Phys. D Nonlinear Phenom. , vol.98 , pp. 33-52
    • Mestl, T.1    Lemay, C.2    Glass, L.3
  • 31
    • 77956297973 scopus 로고    scopus 로고
    • Efficient estimation of the robustness region of biological models with oscillatory behavior
    • doi:10.1371/journal.pone.0009865
    • Apri, M., Molenaar, J., de Gee, M. & van Voorn, G. 2010 Efficient estimation of the robustness region of biological models with oscillatory behavior. PLoS ONE 5, e9865. (doi:10.1371/journal.pone.0009865)
    • (2010) PLoS ONE , vol.5
    • Apri, M.1    Molenaar, J.2    De Gee, M.3    Van Voorn, G.4
  • 32
    • 50849100115 scopus 로고    scopus 로고
    • Floquet theory: A useful tool for understanding nonequilibrium dynamics
    • doi:10.1007/s12080-008-0016-2
    • Klausmeier, C. A. 2008 Floquet theory: a useful tool for understanding nonequilibrium dynamics. Theor. Ecol. 1, 153-161. (doi:10.1007/s12080-008-0016- 2)
    • (2008) Theor. Ecol. , vol.1 , pp. 153-161
    • Klausmeier, C.A.1
  • 34
    • 34548742372 scopus 로고    scopus 로고
    • Modelling the Hes1 oscillator
    • doi:10.1089/cmb.2007.0029
    • Zeiser, S., Muller, J. & Liebscher, V. 2007 Modelling the Hes1 oscillator. J. Comput. Biol. 14, 984-1000. (doi:10.1089/cmb.2007.0029)
    • (2007) J. Comput. Biol. , vol.14 , pp. 984-1000
    • Zeiser, S.1    Muller, J.2    Liebscher, V.3
  • 35
    • 79952715037 scopus 로고    scopus 로고
    • Signal processing in cellular clocks
    • doi:10.1073/pnas.1004720108
    • Forger, D. B. 2010 Signal processing in cellular clocks. Proc. Natl Acad. Sci. USA 108, 4281-4285. (doi:10.1073/pnas.1004720108)
    • (2010) Proc. Natl Acad. Sci. USA , vol.108 , pp. 4281-4285
    • Forger, D.B.1
  • 36
    • 73349138265 scopus 로고    scopus 로고
    • Dependence of the period on the rate of protein degradation inminimal models for circadian oscillations
    • doi:10.1098/rsta.2009.0133
    • Gerard, C., Gonze, D. & Goldbeter, A. 2009 Dependence of the period on the rate of protein degradation inminimal models for circadian oscillations. Philos. Transact. A Math. Phys. Eng. Sci. 367, 4665-4683. (doi:10.1098/rsta. 2009.0133)
    • (2009) Philos. Transact. A Math. Phys. Eng. Sci. , vol.367 , pp. 4665-4683
    • Gerard, C.1    Gonze, D.2    Goldbeter, A.3
  • 37
    • 0033382101 scopus 로고    scopus 로고
    • The Goodwin oscillator: On the importance of degradation reactions in the circadian clock
    • doi:10.1177/074873099129001037
    • Ruoff, P., Vinsjevik, M., Monnerjahn, C. & Rensing, L. 1999 The Goodwin oscillator: on the importance of degradation reactions in the circadian clock. J. Biol. Rhythms. 14, 469-479. (doi:10.1177/074873099129001037)
    • (1999) J. Biol. Rhythms. , vol.14 , pp. 469-479
    • Ruoff, P.1    Vinsjevik, M.2    Monnerjahn, C.3    Rensing, L.4
  • 38
    • 56749160113 scopus 로고    scopus 로고
    • Design principles of biochemical oscillators
    • doi:10.1038/nrm2530
    • Novak, B. & Tyson, J. J. 2008 Design principles of biochemical oscillators. Nat. Rev. Mol. Cell Biol. 9, 981-991. (doi:10.1038/nrm2530)
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 981-991
    • Novak, B.1    Tyson, J.J.2
  • 39
    • 52949098296 scopus 로고    scopus 로고
    • Frequency-modulated nuclear localization bursts coordinate gene regulation
    • doi:10.1038/nature07292
    • Cai, L., Dalal, C. K. & Elowitz, M. B. 2008 Frequency-modulated nuclear localization bursts coordinate gene regulation. Nature 455, 485-490. (doi:10.1038/nature07292)
    • (2008) Nature , vol.455 , pp. 485-490
    • Cai, L.1    Dalal, C.K.2    Elowitz, M.B.3
  • 40
    • 0030019847 scopus 로고    scopus 로고
    • Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1,4,5-trisphosphate production in HeLa cells
    • Bootman, M. D., Young, K. W., Young, J. M., Moreton, R. B. & Berridge, M. J. 1996 Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1,4,5-trisphosphate production in HeLa cells. Biochem. J. 314(Pt 1), 347-354.
    • (1996) Biochem. J. , vol.314 , Issue.PART 1 , pp. 347-354
    • Bootman, M.D.1    Young, K.W.2    Young, J.M.3    Moreton, R.B.4    Berridge, M.J.5
  • 41
    • 0025138491 scopus 로고
    • Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation
    • doi:10.1073/pnas.87.4.1461
    • Goldbeter, A., Dupont, G. & Berridge, M. J. 1990 Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. Proc. Natl Acad. Sci. USA 87, 1461-1465. (doi:10.1073/pnas.87.4.1461)
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 1461-1465
    • Goldbeter, A.1    Dupont, G.2    Berridge, M.J.3
  • 42
    • 0037587790 scopus 로고    scopus 로고
    • A recessive mutant of Drosophila clock reveals a role in circadian rhythm amplitude
    • doi:10.1093/emboj/cdg318
    • Allada, R., Kadener, S., Nandakumar, N. & Rosbash, M. 2003 A recessive mutant of Drosophila clock reveals a role in circadian rhythm amplitude. EMBO J. 22, 3367-3375. (doi:10.1093/emboj/cdg318)
    • (2003) EMBO J. , vol.22 , pp. 3367-3375
    • Allada, R.1    Kadener, S.2    Nandakumar, N.3    Rosbash, M.4
  • 43
    • 0034019315 scopus 로고    scopus 로고
    • Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
    • doi:10.1046/j.1432-1327.2000.01197.x
    • Kholodenko, B. N. 2000 Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. Eur. J. Biochem. 267, 1583-1588. (doi:10.1046/j.1432-1327.2000.01197.x)
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1583-1588
    • Kholodenko, B.N.1
  • 44
    • 42049116557 scopus 로고    scopus 로고
    • FGF induces oscillations of Hes1 expression and Ras/ERK activation
    • doi:10.1016/j.cub.2008.03.013
    • Nakayama, K., Satoh, T., Igari, A., Kageyama, R. &Nishida, E. 2008 FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr. Biol. 18, R332-R334. (doi:10.1016/j.cub.2008.03.013)
    • (2008) Curr. Biol. , vol.18
    • Nakayama, K.1    Satoh, T.2    Igari, A.3    Kageyama, R.4    Nishida, E.5
  • 45
    • 0034129362 scopus 로고    scopus 로고
    • Periodic patterns in biology
    • doi:10.1007/s001140050704
    • Hess, B. 2000 Periodic patterns in biology. Naturwissenschaften 87, 199-211. (doi:10.1007/s001140050704)
    • (2000) Naturwissenschaften , vol.87 , pp. 199-211
    • Hess, B.1
  • 46
    • 78349313665 scopus 로고    scopus 로고
    • Oscillatory control of signalling molecules
    • doi:10.1016/j.gde.2010.08.004
    • Paszek, P., Jackson, D. A. & White, M. R. 2010 Oscillatory control of signalling molecules. Curr. Opin. Genet. Dev. 20, 670-676. (doi:10.1016/j.gde. 2010.08.004)
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 670-676
    • Paszek, P.1    Jackson, D.A.2    White, M.R.3
  • 47
    • 0013770047 scopus 로고
    • Oscillations of glycolytic intermediates in yeast cells
    • doi:10.1016/0006-291X(64)90357-2
    • Ghosh, A. & Chance, B. 1964 Oscillations of glycolytic intermediates in yeast cells. Biochem. Biophys. Res. Commun. 16, 174-181. (doi:10.1016/0006- 291X(64)90357-2)
    • (1964) Biochem. Biophys. Res. Commun. , vol.16 , pp. 174-181
    • Ghosh, A.1    Chance, B.2
  • 48
    • 0037118077 scopus 로고    scopus 로고
    • Circadian rhythms from flies to human
    • doi:10.1038/417329a
    • Panda, S., Hogenesch, J. B. & Kay, S. A. 2002 Circadian rhythms from flies to human. Nature 417, 329-335. (doi:10.1038/417329a)
    • (2002) Nature , vol.417 , pp. 329-335
    • Panda, S.1    Hogenesch, J.B.2    Kay, S.A.3
  • 49
    • 0035926571 scopus 로고    scopus 로고
    • Regulation of the eukaryotic cell cycle: Molecular antagonism, hysteresis, and irreversible transitions
    • doi:10.1006/jtbi.2001.2293
    • Tyson, J. J. & Novak, B. 2001 Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. J. Theor. Biol. 210, 249-263. (doi:10.1006/jtbi.2001.2293)
    • (2001) J. Theor. Biol. , vol.210 , pp. 249-263
    • Tyson, J.J.1    Novak, B.2
  • 50
    • 0035130932 scopus 로고    scopus 로고
    • Calcium signaling: An overview
    • doi:10.1006/scdb.2000.0211
    • Bootman, M. D. et al. 2001 Calcium signaling: an overview. Semin. Cell Dev. Biol. 12, 3-10. (doi:10.1006/scdb.2000.0211)
    • (2001) Semin. Cell Dev. Biol. , vol.12 , pp. 3-10
    • Bootman, M.D.1
  • 51
    • 0033915947 scopus 로고    scopus 로고
    • Ruled by waves? Intracellular and intercellular calcium signalling
    • doi:10.1046/j.1365-201x.2000.00732.x
    • Rottingen, J. & Iversen, J. G. 2000 Ruled by waves? Intracellular and intercellular calcium signalling. Acta Physiol. Scand. 169, 203-219. (doi:10.1046/j.1365-201x.2000.00732.x)
    • (2000) Acta Physiol. Scand. , vol.169 , pp. 203-219
    • Rottingen, J.1    Iversen, J.G.2
  • 52
    • 0031827563 scopus 로고    scopus 로고
    • The role of chaos in neural systems
    • doi:10.1016/S0306-4522(98)00091-8
    • Rabinovich, M. I. & Abarbanel, H. D. 1998 The role of chaos in neural systems. Neuroscience 87, 5-14. (doi:10.1016/S0306-4522(98)00091-8)
    • (1998) Neuroscience , vol.87 , pp. 5-14
    • Rabinovich, M.I.1    Abarbanel, H.D.2
  • 53
    • 38349013623 scopus 로고    scopus 로고
    • Coupled feedback loops form dynamic motifs of cellular networks
    • doi:10.1529/biophysj.107.105106
    • Kim, J. R., Yoon, Y. & Cho, K. H. 2008 Coupled feedback loops form dynamic motifs of cellular networks. Biophys. J. 94, 359-365. (doi:10.1529/biophysj.107.105106)
    • (2008) Biophys. J. , vol.94 , pp. 359-365
    • Kim, J.R.1    Yoon, Y.2    Cho, K.H.3
  • 54
    • 79952638264 scopus 로고    scopus 로고
    • Cellular decision making and biological noise: From microbes to mammals
    • doi:10.1016/j.cell.2011.01.030
    • Balazsi, G., van Oudenaarden, A. & Collins, J. J. 2011 Cellular decision making and biological noise: from microbes to mammals. Cell 144, 910-925. (doi:10.1016/j.cell.2011.01.030)
    • (2011) Cell , vol.144 , pp. 910-925
    • Balazsi, G.1    Van Oudenaarden, A.2    Collins, J.J.3
  • 55
    • 33745725673 scopus 로고    scopus 로고
    • The effect of negative feedback on noise propagation in transcriptional gene networks
    • doi:10.1063/1.2208927
    • Hooshangi, S. & Weiss, R. 2006 The effect of negative feedback on noise propagation in transcriptional gene networks. Chaos 16, 026108. (doi:10.1063/1.2208927)
    • (2006) Chaos , vol.16 , pp. 026108
    • Hooshangi, S.1    Weiss, R.2
  • 56
    • 68049139445 scopus 로고    scopus 로고
    • Optimal feedback strength for noise suppression in autoregulatory gene networks
    • doi:10.1016/j.bpj.2009.02.064
    • Singh, A. & Hespanha, J. P. 2009 Optimal feedback strength for noise suppression in autoregulatory gene networks. Biophys. J. 96, 4013-4023. (doi:10.1016/j.bpj.2009.02.064)
    • (2009) Biophys. J. , vol.96 , pp. 4013-4023
    • Singh, A.1    Hespanha, J.P.2


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