Distribution of gentamicin in the guinea pig inner ear after local or systemic application

JARO - Journal of the Association for Research in Otolaryngology

Volumn 4, Issue 2, 2003, Pages 176-195

  Imaimura, Shun Ichi ^a   Adams, Joe C ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

Aminoglycoside; Immunocytochemistry; Inner ear; Ototoxicity

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM; CELL SURVIVAL; CELL TYPE; COCHLEA INJURY; CONTROLLED STUDY; CORTI ORGAN; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG RETENTION; DRUG UPTAKE; FIBROCYTE; GUINEA PIG; HAIR CELL; IMMUNOCYTOCHEMISTRY; INNER EAR; LIGAMENT; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; STRIA VASCULARIS; VESTIBULAR DISORDER; VESTIBULAR SYSTEM;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; BASILAR MEMBRANE; COCHLEAR DUCT; EAR, INNER; GENTAMICINS; GUINEA PIGS; INJECTIONS, INTRAPERITONEAL; ORGAN OF CORTI; SPIRAL GANGLION; STRIA VASCULARIS; VESTIBULE;

EID: 0037972273     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10162-002-2036-8     Document Type: Article

References (59)

1. ADAMS JC. Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains. J. Histochem. Cytochem. 40:1457-1463, 1992.
2. ARAN JM, ERRE JP, LIMA DA COSTA D, DEBBARH I, DULON D. Acute and chronic effects of aminoglycosides on cochlear hair cells. Ann. N. Y. Acad. Sci. 884:60-68, 1999.
3. BALOGH K, HIRAIDE F, ISHI D. Distribution of radioactive dihydrostreptomycin in the cochlea - an autoradiographic study. Ann. Otol. (St. Louis) 79:641-652, 1970.
4. BLAKLEY BW. Update on intratympanic gentamicin for Meniere's disease. Laryngoscope 110:236-240, 2000.
5. BRUMMETT RE, TRAYNOR J, BROWN R, HIMES D. Cochlear damage resulting from kanamycin and furosemide. Acta Otolaryngol. 80:86-92, 1975.
6. BRYANT GM, CRONIN-SCHREIBER R, ALEXANDER A, NORRIS CH, QUINE PS, GUTH PS. The potentiation of ototoxicity when aminooxyacetic acid and kanamycin are co-administered. Hear. Res. 15:173-178, 1984.
7. CONLON BJ, MCSWAIN SD, SMITH DW. Topical gentamicin and ethacrynic acid: effects on cochlear function. Laryngoscope 108:1087-1089, 1998.
8. COTANCHE DA. Structural recovery from sound and aminoglycoside damage in the avian cochlea. Audiol. Neurootol. 4:271-285, 1999.
9. DECICCO MJ, HOFFER ME, KOPKE RD, WESTER D, ALLEN KA, GOTTSHALL K, O'LEARY MJ. Round-window microcatheter-administered microdose gentamicin: results from treatment of tinnitus associated with Meniere's disease. Int. Tinnitus J. 4:141-143, 1998.
10. DEGROOT JCMJ, MEEUWSEN F, RUIZENTAAL WE, VELDMAN JE. Ultrastructural localization of gentamicin. Hear. Res. 50:35-42, 1990.
11. DULON D, ARAN JM, ZAJIC G, SCHACHT J. Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule. Antimicrob. Agents Chemother. 30:96-100, 1986.
12. DULON D, HIEL H, AUROUSSEAU C, ERRE JP, ARAN JM. Pharmacokinetics of gentamicin in the sensory hair cells of the organ of Corti: rapid uptake and long term persistence. C. R. Acad. Sci. III. 316:682-687, 1993.
13. FEDERSPIL P. Pharmacokinetics of aminoglycoside antibiotics in the perilymph. In: Lerner SA, Mats GJ, Hawkins Jr. JE (eds) Aminoglycoside Ototoxicity. Boston, Little Brown, 1981, pp 99-108
14. FORGE A, SCHACHT J. Aminoglycoside antibiotics. Audiol. Neurootol. 5:3-22, 2000.
15. GAO WQ. Therapeutic potential of neurotrophins for treatment of hearing loss. Mol. Neurobiol. 17:17-31, 1998.
16. HASHINO E, SHERO M. Endocytosis of aminoglycoside antibiotics in sensory hair cells. Brain Res. 704:135-140, 1995.
17. HASHINO E, SHERO M, SALVI RJ. Lysosomal targeting and accumulation of aminoglycoside antibiotics in sensory hair cells. Brain Res. 777:75-85, 1997.
18. HAWKINS JR JE. Comparative otopathology: aging, noise, and ototoxic drugs. Adv. Otorhinolaryngol. 20:125-141, 1973.
19. HAWKINS JR JE, JOHNSSON LG. Histopathology of cochlear and vestibular ototoxicity. In: Lerner SA, Mats GJ, Hawkins Jr JE (eds) Aminoglycoside ototoxicity Little Brown, Boston, 1981, pp 175-195
20. HAYASHIDA T, NOMURA Y, IWAMORI M, NAGAI Y, KURATA T. Distribution of gentamicin by immunofluorescence in the guinea pig inner ear. Arch. Otorhinolaryngol. 242:257-264, 1985.
21. HAYASHIDA T. An immunohistochemical method for the study of aminoglycoside ototoxicity in the guinea pig cochlea using decalcified frozen sections. Arch. Otorhinolaryngol. 246:161-164, 1989.
22. HAYASHIDA T, HIEL H, DULON D, ERRE JP, GUIHAUME A, ARAN JM. Dynamic changes following combined treatment with gentamicin and ethacrynic acid with and without acoustic stimulation. Acta Otolaryngol. (Stockh.) 108:404-413, 1989.
23. HIEL H, BENNANI H, ERRE J, AUROUSSEAU C, ARAN J. Kinetics of gentamicin in cochlear hair cells after chronic treatment. Acta Otolaryngol. (Stockh.) 112:272-277, 1992a.
24. HIEL H, SCHAMEL A, ERRE J, HAYASHIDA T, DULON D, ARAN J. Cellular and subcellular localization of tritiated gentamicin in the guinea pig cochlea following combined treatment with ethacrynic acid. Hear. Res. 57:157-165, 1992b.
25. HIEL H, ERRE J, AUROUSSEAU C, BOUALI R, DULON D, ARAN J. Gentamicin uptake by cochlear hair cells precedes hearing impairment during chronic treatment. Audiology 32:78-87, 1993.
26. HUSMANN KR, MORGAN AS, GIROD DA, DURHAM D. Round window administration of gentamicin: a new method for the study of ototoxicity of cochlear hair cells. Hear. Res. 125:109-119, 1998.
27. ICHIMIYA I, ADAMS JC, KIMURA R. Changes in immunostaining of cochleas with experimentally induced endolymphatic hydrops. Ann. Otol. Rhinol. Laryngol. 103:457-468, 1994.
28. IMAMURA S, ADAMS JC. Immunolocalization of peptide 19 and other calcium-binding proteins in the guinea pig cochlea. Anat. Embryol. (Berl.) 194:407-418, 1996.
29. IWAMORI M, TAYAMA N, NOMURA Y, NAGAI Y. Hormone-dependent enhancement in binding of oto- and nephrotoxic aminoglycoside antibiotics. Acta Otolaryngol. Suppl. (Stockh.) 514:117-121, 1994.
30. KIKUCHI T, KIMURA RS, ADAMS JC. Gap junctions in the rat cochlea: immunohistochemical and ultrastructural analysis. Anat. Embryol. (Berl.) 191:101-118, 1995.
31. KIMURA RS, LEE K-S, NYE CL, TREHEY JA. Effects of systemic and lateral semicircular canal administration of aminoglycosides on normal and hydropic inner ears. Acta Otolaryngol. (Stockh.) 111:1021-1030, 1991.
32. LEAKE PA, SNYDER RL. Uptake of horseradish peroxidase from perilymph by cochlear hair cells. Hear. Res. 25:153-171, 1987.
33. MARZELLA PL, CLARK GM. Growth factors, auditory neurones and cochlear implants: a review. Acta Otolaryngol. 119:407-412, 1999.
34. MEYER J, MACK AL, GUMMER AW. Pronounced infracuticular-endocytosis in mammalian outer hair cells. Hear. Res. 161:10-22, 2001.
35. MUGNAINI E, DAHL AL. Zinc-aldehyde fixation for light-microscopic immunocytochemistry of nervous tissues. J. Histochem. Cytochem. 31:1435-1438, 1983.
36. NADOL JB, ADAMS JC, KIM JR. Degenerative changes in the organ of Corti and lateral cochlear wall in experimental endolymphatic hydrops and human Meniere's disease. Acta Otolaryngol. Suppl. (Stockh.) 519:47-59, 1995.
37. NAKASHIMA T, TERANISHI M, HIBI T, KOBAYASHI M, UMEMURA M. Vestibular and cochlear toxicity of aminoglycosides - a review. Acta Otolaryngol. 120:904-911, 2000.
38. PORTMAN M, DARROUZET J, COSTE C. Distribution within the cochlea of dihydrostreptomycin injected into the circulation. Arch. Otolaryngol. (Chicago). 100:473-475, 1974.
39. RICHARDSON GP, FORGE A, CROS CJ, FLEMING J, BROWN SD, STEEL KP. Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells. J. Neurosci. 17:9506-9519, 1997.
40. RYBACK LP. Ototoxic mechanisms. In: Altschuler RA, Bobbin RP, Hoffman DW (eds) Neurobiology of hearing: the cochlea. Raven Press, New York, 1986, pp 442-454
41. SCHACHT J. Molecular mechanisms of drug-induced hearing loss. Hear. Res. 22:297-304, 1986.
42. SCHACHT J. Biochemical basis of aminoglycoside ototoxicity. Otolaryngol. Clin. N. Am. 26:845-856, 1993.
43. +-ATPase in gerbil cochlea. J. Histochem Cytochem. 37:127-134, 1989.
44. SIEGEL JH, BROWNELL WE. Synaptic and golgi membrane recycling in cochlear hair cells. J. Neurocytol. 15:311-328, 1986.
45. SPICER SS, SCHULTE BA. Golgi-canalicular reticulum system in ion transporting fibrocytes and outer sulcus epithelium of gerbil cochlea. Anat. Rec. 249:117-127, 1997.
46. SPICER SS, THOMOPOULOS GN, SCHULTE BA. Cytologic evidence for mechanisms of K+ transport and genesis of Hensen bodies and subsurface cisternae in outer hair cells. Anat. Rec. 251:97-113, 1998.
47. STONE JS, RUBEL EW. Cellular studies of auditory hair cell regeneration in birds. Proc. Natl. Acad. Sci. U S A 97:11714-11721, 2000.
48. TACHIBANA M, MORIOKA H, MACHINO M, MIZUKOSHI O. Binding sites of an aminoglycoside in the cochlea examined by immunocytochemistry. Histochemistry, 83:237-240, 1985.
49. TAKADA A, BLEDSOE JR S, SCHACHT J. An energy-dependent step in aminoglycoside ototoxicity: prevention of gentamicin ototoxicity during reduced endolymphatic potential. Hear. Res. 19:245-251, 1985.
50. TRAN BA HUY P, MANUEL C, MEULEMANS A. Kinetics of aminoglycoside antibiotics in perilymph and endolymph in animals. In: Lerner SA, Mats GJ, Hawkins Jr JE (eds) Aminoglycoside ototoxicity. Little, Brown, Boston, 1981a, pp 81-97
51. TRAN BA HUY P, MANUEL C, MEULEMANS A, STERKERS O, AMIEL C. Pharmacokinetics of gentamicin in perilymph and endolymph of the rat as determined by radioimmunoassay. J. Infect. Dis. 143:476-486, 1981b.
52. TRAN BA HUY P, MEULEMANS A, WASSEF M, MANUEL C, STERKERS O, AMIEL C. Gentamicin persistent in rat endolymph and perilymph after two-day constant infusion. Antimicrob. Agents Chemther. 23:344-346, 1983.
53. TRAN BA HUY P, BERNARD P, SCHACHT J. Kinetics of gentamicin uptake and release in the rat; comparison of inner ear tissues and fluids with others organs. J. Clin. Invest. 77:1492-1500, 1986.
54. VELDMAN JE, MEEUWSEN F, VAN DIJK M, KEY Q, HUIZING EH. Progress in temporal bone histopathology. II. Immuno-technology applied to the temporal bone. Acta Otolaryngol. Suppl. 423:29-35, 1985.
55. VON ILBERG C, SPOENDLIN H, ARNOLD W. Auto radiographical distribution of locally applied dihydrostreptomycin in the inner ear. Acta Otolaryngol. (Stockh.) 71:159-165, 1971.
56. WERSALL J, LUNDQUIST PG, BJORKROTH B. Ototoxicity of gentamicin. J. Infect. Dis. 119:410-416, 1969.
57. WERSALL J. Ototoxic antibiotics: a review. Acta Otolaryngol. Suppl. 519:26-29, 1995.
58. WILLIAMS SE, ZENNER HP, SCHACHT J. Three molecular steps aminoglycoside ototoxicity demonstrated in outer hair cells. Hear. Res. 30:11-18, 1987.
59. YAMANE H, NAKAI Y, KONISHI K. Furosemide-induced alteration of drug pathway to cochlea. Acta Otolaryngol. Suppl. 447:28-35, 1988.