-
1
-
-
0034682892
-
Genes expressed in human tumor endothelium
-
St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, et al. (2000) Genes expressed in human tumor endothelium. Science 289: 1197-1202.
-
(2000)
Science
, vol.289
, pp. 1197-1202
-
-
St Croix, B.1
Rago, C.2
Velculescu, V.3
Traverso, G.4
Romans, K.E.5
-
2
-
-
0035829509
-
Identification of the cellular receptor for anthrax toxin
-
Bradley KA, Mogridge J, Mourez M, Collier RJ, Young JA, (2001) Identification of the cellular receptor for anthrax toxin. Nature 414: 225-229.
-
(2001)
Nature
, vol.414
, pp. 225-229
-
-
Bradley, K.A.1
Mogridge, J.2
Mourez, M.3
Collier, R.J.4
Young, J.A.5
-
3
-
-
0013159236
-
Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalizations
-
Liu S, Leppla SH, (2003) Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalizations. J Biol Chem 278: 5227-5234.
-
(2003)
J Biol Chem
, vol.278
, pp. 5227-5234
-
-
Liu, S.1
Leppla, S.H.2
-
4
-
-
0038303163
-
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor
-
Scobie HM, Rainey GJ, Bradley KA, Young JA, (2003) Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci USA, 100(9): 5170-5174.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.9
, pp. 5170-5174
-
-
Scobie, H.M.1
Rainey, G.J.2
Bradley, K.A.3
Young, J.A.4
-
5
-
-
13444274554
-
Interactions between anthrax toxin receptors and protective antigen
-
Scobie HM, Young JA, (2005) Interactions between anthrax toxin receptors and protective antigen. Curr Opin Microbiol 8(1): 106-112.
-
(2005)
Curr Opin Microbiol
, vol.8
, Issue.1
, pp. 106-112
-
-
Scobie, H.M.1
Young, J.A.2
-
6
-
-
0034870220
-
Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation, and G-protein signaling
-
Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, et al. (2001) Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation, and G-protein signaling. J Cell Sci 114: 2755-2773.
-
(2001)
J Cell Sci
, vol.114
, pp. 2755-2773
-
-
Bell, S.E.1
Mavila, A.2
Salazar, R.3
Bayless, K.J.4
Kanagala, S.5
-
7
-
-
1542782211
-
Binding of anthrax to its receptor is similar to α-integrin-ligand interactions
-
Bradley KA, Mogridge J, Jonah G, Rainey A, Batty S, Young JAT, (2003) Binding of anthrax to its receptor is similar to α-integrin-ligand interactions. J Biol Chem 278: 49342-49347.
-
(2003)
J Biol Chem
, vol.278
, pp. 49342-49347
-
-
Bradley, K.A.1
Mogridge, J.2
Jonah, G.3
Rainey, A.4
Batty, S.5
Young, J.A.T.6
-
9
-
-
70350728404
-
Receptors of anthrax toxin and cell entry
-
Van der Goot G, Young JA, (2009) Receptors of anthrax toxin and cell entry. Mol Aspects Med 30 (6): 406-412.
-
(2009)
Mol Aspects Med
, vol.30
, Issue.6
, pp. 406-412
-
-
van der Goot, G.1
Young, J.A.2
-
10
-
-
0000947082
-
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
-
Leppla SH, (1982) Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci USA 79: 3162-3166.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 3162-3166
-
-
Leppla, S.H.1
-
11
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase kinase by anthrax lethal factor
-
Duesbery NS, Webb CP, Leppla SH, Gordon VM, Klimpel KR, et al. (1998) Proteolytic inactivation of MAP-kinase kinase by anthrax lethal factor. Science 280: 734-737.
-
(1998)
Science
, vol.280
, pp. 734-737
-
-
Duesbery, N.S.1
Webb, C.P.2
Leppla, S.H.3
Gordon, V.M.4
Klimpel, K.R.5
-
12
-
-
0028088404
-
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
-
Klimpel KR, Arora N, Leppla SH, (1994) Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol Microbiol 13: 1093-1100.
-
(1994)
Mol Microbiol
, vol.13
, pp. 1093-1100
-
-
Klimpel, K.R.1
Arora, N.2
Leppla, S.H.3
-
13
-
-
0032755353
-
Anthrax lethal factor cleaves MKK3 in Macrophages and inhibits the LPS/IFN-γ-induced release of NO and TNF-α
-
Pellizzari R, Guidi-Rontani C, Vitale G, Mock M, Montecucco C, (1999) Anthrax lethal factor cleaves MKK3 in Macrophages and inhibits the LPS/IFN-γ-induced release of NO and TNF-α. FEBS Lett 462: 199-204.
-
(1999)
FEBS Lett
, vol.462
, pp. 199-204
-
-
Pellizzari, R.1
Guidi-Rontani, C.2
Vitale, G.3
Mock, M.4
Montecucco, C.5
-
14
-
-
0034672216
-
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
-
Vitale G, Bernardi L, Napolitani G, Mock M, Montecucco C, (2000) Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem J 352: 739-745.
-
(2000)
Biochem J
, vol.352
, pp. 739-745
-
-
Vitale, G.1
Bernardi, L.2
Napolitani, G.3
Mock, M.4
Montecucco, C.5
-
15
-
-
0032581369
-
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
-
Vitale G, Pellizzari R, Recchi C, Napolitani G, Mock M, et al. (1998) Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochem Biophys Res Commun 248: 706-711.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 706-711
-
-
Vitale, G.1
Pellizzari, R.2
Recchi, C.3
Napolitani, G.4
Mock, M.5
-
16
-
-
0346251030
-
Anthrax lethal toxin induces human endothelial cell apoptosis
-
Kirby JE, (2004) Anthrax lethal toxin induces human endothelial cell apoptosis. Infect Immun 72: 430-439.
-
(2004)
Infect Immun
, vol.72
, pp. 430-439
-
-
Kirby, J.E.1
-
17
-
-
0037144590
-
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
-
Park JM, Greten FR, Li ZW, Karin M, (2002) Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297: 2048-2051.
-
(2002)
Science
, vol.297
, pp. 2048-2051
-
-
Park, J.M.1
Greten, F.R.2
Li, Z.W.3
Karin, M.4
-
18
-
-
0036295213
-
Lethal toxin of Bacillus anthracis causes apoptosis of macrophages
-
Popov SG, Villasmil R, Bernardi J, Grene E, Cardwell J, et al. (2002) Lethal toxin of Bacillus anthracis causes apoptosis of macrophages. Biochem Biophys Res Commun 293: 349-355.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 349-355
-
-
Popov, S.G.1
Villasmil, R.2
Bernardi, J.3
Grene, E.4
Cardwell, J.5
-
19
-
-
0037022666
-
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
-
Koo HM, VanBrocklin M, McWilliams MJ, Leppla SH, Duesbery NS, et al. (2002) Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proc Natl Acad Sci USA 99 (5): 3052-3057.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.5
, pp. 3052-3057
-
-
Koo, H.M.1
VanBrocklin, M.2
McWilliams, M.J.3
Leppla, S.H.4
Duesbery, N.S.5
-
20
-
-
0028872463
-
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
-
Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla SH, (1995) Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect Immun 63: 82-87.
-
(1995)
Infect Immun
, vol.63
, pp. 82-87
-
-
Gordon, V.M.1
Klimpel, K.R.2
Arora, N.3
Henderson, M.A.4
Leppla, S.H.5
-
21
-
-
0026498189
-
Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin
-
Klimpel KR, Molloy SS, Thomas G, Leppla SH, (1992) Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin. Proc Natl Acad Sci USA 89: 10277-10281.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10277-10281
-
-
Klimpel, K.R.1
Molloy, S.S.2
Thomas, G.3
Leppla, S.H.4
-
22
-
-
0028018856
-
Anthrax protective antigen forms oligomers during intoxication of mammalian cells
-
Milne JC, Furlong D, Hanna PC, Wall JS, Collier RJ, (1994) Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem 269 (32): 20607-20612.
-
(1994)
J Biol Chem
, vol.269
, Issue.32
, pp. 20607-20612
-
-
Milne, J.C.1
Furlong, D.2
Hanna, P.C.3
Wall, J.S.4
Collier, R.J.5
-
24
-
-
0037076364
-
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen
-
Mogridge J, Cunningham K, Lacy DB, Mourez M, Collier RJ, (2002) The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proc Natl Acad Sci USA 99 (10): 7045-7048.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.10
, pp. 7045-7048
-
-
Mogridge, J.1
Cunningham, K.2
Lacy, D.B.3
Mourez, M.4
Collier, R.J.5
-
25
-
-
0022891493
-
Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
-
Friedlander AM, (1986) Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem 261: 7123-7126.
-
(1986)
J Biol Chem
, vol.261
, pp. 7123-7126
-
-
Friedlander, A.M.1
-
26
-
-
0842304298
-
TEM8 interacts with the cleaved C5 domain of collagen alpha-3(VI)
-
Nanda A, Carson-Walter EB, Seaman S, Barber TD, Stampfl J, Singh S, et al. (2004) TEM8 interacts with the cleaved C5 domain of collagen alpha-3(VI). Cancer Res 64: 817-820.
-
(2004)
Cancer Res
, vol.64
, pp. 817-820
-
-
Nanda, A.1
Carson-Walter, E.B.2
Seaman, S.3
Barber, T.D.4
Stampfl, J.5
Singh, S.6
-
27
-
-
7744247059
-
Upregulation of tumour endothelial marker-8 by interleukin-1-alpha induced angiogenesis
-
Rmali KA, Al-Rawi MAA, Parr C, Puntis MCA, Jiang WG, (2004) Upregulation of tumour endothelial marker-8 by interleukin-1-alpha induced angiogenesis. Int J Mol Med 14: 75-80.
-
(2004)
Int J Mol Med
, vol.14
, pp. 75-80
-
-
Rmali, K.A.1
Al-Rawi, M.A.A.2
Parr, C.3
Puntis, M.C.A.4
Jiang, W.G.5
-
28
-
-
22144453604
-
TEM-8 and tubule formation in endothelial cells, potential role of its vWA/TM domains
-
Rmali KA, Parr C, Puntis MCA, Jiang WG, (2005) TEM-8 and tubule formation in endothelial cells, potential role of its vWA/TM domains. Biochem Biophys Res Commun 334: 231-238.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 231-238
-
-
Rmali, K.A.1
Parr, C.2
Puntis, M.C.A.3
Jiang, W.G.4
-
29
-
-
0035884593
-
Cell surface tumor endothelial markers are conserved in mice and humans
-
Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, et al. (2001) Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Res 61: 6649-6655.
-
(2001)
Cancer Res
, vol.61
, pp. 6649-6655
-
-
Carson-Walter, E.B.1
Watkins, D.N.2
Nanda, A.3
Vogelstein, B.4
Kinzler, K.W.5
-
30
-
-
33748556500
-
Quantitative measurement of anthrax toxin receptor messenger RNA in primary mononuclear phagocytes
-
Premanandan C, Lairmore MD, Fernandez S, Phipps AJ, (2006) Quantitative measurement of anthrax toxin receptor messenger RNA in primary mononuclear phagocytes. Microb Pathog 41: 193-198.
-
(2006)
Microb Pathog
, vol.41
, pp. 193-198
-
-
Premanandan, C.1
Lairmore, M.D.2
Fernandez, S.3
Phipps, A.J.4
-
31
-
-
0026741811
-
Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells
-
Arora N, Klimpel KR, Singh Y, Leppla SH, (1992) Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells. J Biol Chem 267: 15542-15548.
-
(1992)
J Biol Chem
, vol.267
, pp. 15542-15548
-
-
Arora, N.1
Klimpel, K.R.2
Singh, Y.3
Leppla, S.H.4
-
32
-
-
0037415611
-
Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent path
-
Abrami L, Liu S, Cosson P, Leppla SH, van der Goot FG, (2003) Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent path. J Cell Biol 160: 321-328.
-
(2003)
J Cell Biol
, vol.160
, pp. 321-328
-
-
Abrami, L.1
Liu, S.2
Cosson, P.3
Leppla, S.H.4
van der Goot, F.G.5
-
33
-
-
34447291354
-
Anthrax toxin: receptor binding, internalization, pore formation, and translocation
-
Young JAT, Collier RJ, (2007) Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annu Rev Biochem 76: 243-65.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 243-265
-
-
Young, J.A.T.1
Collier, R.J.2
-
34
-
-
77950407292
-
Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors
-
Abrami L, Bischofberger B, Kunz R, Groux F, van der Goot FG, (2010) Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors. PLoS Pathog 6: e1000792.
-
(2010)
PLoS Pathog
, vol.6
-
-
Abrami, L.1
Bischofberger, B.2
Kunz, R.3
Groux, F.4
van der Goot, F.G.5
-
35
-
-
69349098830
-
The protective antigen component of anthrax toxin forms functional octameric complexes
-
Kintzer AF, Thoren KL, Sterling HJ, Dong KC, Feld GK, et al. (2009) The protective antigen component of anthrax toxin forms functional octameric complexes. J Mol Biol 392(3): 614-629.
-
(2009)
J Mol Biol
, vol.392
, Issue.3
, pp. 614-629
-
-
Kintzer, A.F.1
Thoren, K.L.2
Sterling, H.J.3
Dong, K.C.4
Feld, G.K.5
-
36
-
-
0036468526
-
Quickening the pace of anthrax research: three advances point towards possible therapies
-
Chaudry GJ, Moayeri M, Liu S, Leppla SH, (2002) Quickening the pace of anthrax research: three advances point towards possible therapies. Trends Microbiol: 10,: 58-62.
-
(2002)
Trends Microbiol
, vol.10
, pp. 58-62
-
-
Chaudry, G.J.1
Moayeri, M.2
Liu, S.3
Leppla, S.H.4
-
37
-
-
22244443676
-
ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection
-
Bonuccelli G, Sotgia F, Frank PG, Williams TM, De Almeida CJ, et al. (2005) ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection. Am J Physiol Cell Physiol 288(6): C1402-1410.
-
(2005)
Am J Physiol Cell Physiol
, vol.288
, Issue.6
-
-
Bonuccelli, G.1
Sotgia, F.2
Frank, P.G.3
Williams, T.M.4
de Almeida, C.J.5
-
38
-
-
2442697761
-
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons
-
De Preter K, Pattyn F, Berx G, Strumane K, Menten B, et al. (2004) Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons. BMC Genomics 5: 11-24.
-
(2004)
BMC Genomics
, vol.5
, pp. 11-24
-
-
de Preter, K.1
Pattyn, F.2
Berx, G.3
Strumane, K.4
Menten, B.5
-
39
-
-
28044440112
-
Characterization of a complex genomic alteration on chromosome 2p that leads to four alternatively spliced fusion transcripts in the neuroblastoma cell lines IMR-5, IMR-5/75, and IMR-32
-
Oberthuer A, Skowron M, Spitz R, Kahlert Y, Westermann F, et al. (2005) Characterization of a complex genomic alteration on chromosome 2p that leads to four alternatively spliced fusion transcripts in the neuroblastoma cell lines IMR-5, IMR-5/75, and IMR-32. Gene 363: 41-50.
-
(2005)
Gene
, vol.363
, pp. 41-50
-
-
Oberthuer, A.1
Skowron, M.2
Spitz, R.3
Kahlert, Y.4
Westermann, F.5
-
40
-
-
68149175255
-
Capillary morphogenesis protein-2 is the major receptor mediating anthrax toxin lethality in vivo
-
Liu S, Crown D, Miller-Randolph S, Moayeri M, Wang H, et al. (2009) Capillary morphogenesis protein-2 is the major receptor mediating anthrax toxin lethality in vivo. Proc Natl Acad Sci 106 (30): 12224-12229.
-
(2009)
Proc Natl Acad Sci
, vol.106
, Issue.30
, pp. 12224-12229
-
-
Liu, S.1
Crown, D.2
Miller-Randolph, S.3
Moayeri, M.4
Wang, H.5
-
41
-
-
76849114681
-
Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis
-
Reeves CV, Dufraine J, Young JA, Kitajewski J, (2010) Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis. Oncogene 29 (6): 789-801.
-
(2010)
Oncogene
, vol.29
, Issue.6
, pp. 789-801
-
-
Reeves, C.V.1
Dufraine, J.2
Young, J.A.3
Kitajewski, J.4
-
42
-
-
15044344225
-
TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen
-
Hotchkiss KA, Basile CM, Spring SC, Bonuccelli G, Lisanti MP, et al. (2005) TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen. Exp Cell Res 305: 133-144.
-
(2005)
Exp Cell Res
, vol.305
, pp. 133-144
-
-
Hotchkiss, K.A.1
Basile, C.M.2
Spring, S.C.3
Bonuccelli, G.4
Lisanti, M.P.5
-
43
-
-
33646019842
-
The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin
-
Wei W, Lu Q, Chaudry GJ, Leppla SH, Cohen SN, (2006) The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin. Cell 124: 1119-1121.
-
(2006)
Cell
, vol.124
, pp. 1119-1121
-
-
Wei, W.1
Lu, Q.2
Chaudry, G.J.3
Leppla, S.H.4
Cohen, S.N.5
-
44
-
-
30944443590
-
Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis
-
Abrami L, Leppla SH, van der Goot FG, (2006) Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis. J Cell Biol 172: 309-20.
-
(2006)
J Cell Biol
, vol.172
, pp. 309-320
-
-
Abrami, L.1
Leppla, S.H.2
van der Goot, F.G.3
-
45
-
-
58449092971
-
The cytoplasmic domain of anthrax toxin receptor 1 affects binding of the protective antigen
-
Go MY, Chow EM, Mogridge J, (2009) The cytoplasmic domain of anthrax toxin receptor 1 affects binding of the protective antigen. Infect Immun 77 (1): 52-59.
-
(2009)
Infect Immun
, vol.77
, Issue.1
, pp. 52-59
-
-
Go, M.Y.1
Chow, E.M.2
Mogridge, J.3
-
46
-
-
78650138302
-
The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton
-
Yang MY, Chaudhary A, Seaman S, Dunty J, Stevens J, et al. (2010) The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton. Biochim Biophys Acta 1813: 39-49.
-
(2010)
Biochim Biophys Acta
, vol.1813
, pp. 39-49
-
-
Yang, M.Y.1
Chaudhary, A.2
Seaman, S.3
Dunty, J.4
Stevens, J.5
|