Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15-O-acetate as the main active compound

Malaria Journal

Volumn 11, Issue , 2012, Pages

  Jansen, Olivia ^a   Tits, Monique ^a   Angenot, Luc ^a   Nicolas, Jean Pierre ^b   De Mol, Patrick ^a   Nikiema, Jean Baptiste ^c   Frédérich, Michel ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b Association Jardins du Monde   (France)

^c UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

Author keywords

Antiplasmodial; Asteraceae; Burkina Faso; Dicoma tomentosa; Melampolide; Natural compound

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; ANTIMALARIAL AGENT; DICHLOROMETHANE; DICOMA TOMENTOSA EXTRACT; ETHER; HOT WATER; MELAMPOLIDE; METHANOL; SESQUITERPENE LACTONE; UNCLASSIFIED DRUG; UROSPERMAL A 15 O ACETATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; DICOMA TOMENTOSA; DRUG IDENTIFICATION; FIBROBLAST; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM BERGHEI INFECTION; PLASMODIUM FALCIPARUM; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

ACETATES; ANIMALS; ANTIMALARIALS; ASTERACEAE; BIOLOGICAL AGENTS; BURKINA FASO; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DISEASE MODELS, ANIMAL; FIBROBLASTS; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA; MICE; PLANT EXTRACTS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SESQUITERPENES; SPECTRUM ANALYSIS; TREATMENT OUTCOME;

EID: 84865064255     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-11-289     Document Type: Article

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