Quetiapine, an atypical antipsychotic, is protective against autoimmune-mediated demyelination by inhibiting effector T cell proliferation

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Mei, Feng ^a   Guo, Sheng ^a   He, Yangtao ^a   Wang, Linyun ^a   Wang, Hongkai ^a   Niu, Jianqin ^a   Kong, Jiming ^b   Li, Xinmin ^b   Wu, Yuzhang ^a   Xiao, Lan ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; QUETIAPINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DRUG EFFICACY; DRUG MECHANISM; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MITOSIS INHIBITION; MOUSE; MULTIPLE SCLEROSIS; NEUROPROTECTION; NONHUMAN;

ANIMALS; ANTIPSYCHOTIC AGENTS; ASTROCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DIBENZOTHIAZEPINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; IMMUNOMODULATION; MICE; MICE, INBRED C57BL; MICROGLIA; MYELIN SHEATH; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; SPINAL CORD;

EID: 84865062102     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042746     Document Type: Article

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