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Volumn 237, Issue 2, 2012, Pages 444-452

Oxidative stress as a therapeutic target in globoid cell leukodystrophy

Author keywords

Bone marrow transplant; Krabbe Disease; Lysosomal storage disease; N acetyl cysteine; Oxidative stress; Twitcher

Indexed keywords

ACETYLCYSTEINE; CD68 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PSYCHOSINE;

EID: 84865048893     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.07.013     Document Type: Article
Times cited : (23)

References (36)
  • 2
    • 34548072307 scopus 로고    scopus 로고
    • N-acetylcysteine-a safe antidote for cysteine/glutathione deficiency
    • Atkuri K.R., Mantovani J.J., Herzenberg L.A. N-acetylcysteine-a safe antidote for cysteine/glutathione deficiency. Curr. Opin. Pharmacol. 2007, 7:355-359.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 355-359
    • Atkuri, K.R.1    Mantovani, J.J.2    Herzenberg, L.A.3
  • 4
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
    • Beckman J.S., Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 1996, 271:C1424-C1437.
    • (1996) Am. J. Physiol. , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 5
    • 0036134280 scopus 로고    scopus 로고
    • Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy
    • Biswas S., LeVine S.M. Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy. Pediatr. Res. 2002, 51:40-47.
    • (2002) Pediatr. Res. , vol.51 , pp. 40-47
    • Biswas, S.1    LeVine, S.M.2
  • 9
    • 0037342554 scopus 로고    scopus 로고
    • The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
    • Farr S.A., Poon H.F., Dogrukol-Ak D., Drake J., Banks W.A., Eyerman E., Butterfield D.A., Morley J.E. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J. Neurochem. 2003, 84:1173-1183.
    • (2003) J. Neurochem. , vol.84 , pp. 1173-1183
    • Farr, S.A.1    Poon, H.F.2    Dogrukol-Ak, D.3    Drake, J.4    Banks, W.A.5    Eyerman, E.6    Butterfield, D.A.7    Morley, J.E.8
  • 10
    • 66049162131 scopus 로고    scopus 로고
    • Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease
    • Galbiati F., Givogri M.I., Cantuti L., Lopez Rosas A., Cao H., van Breemen R., Bongarzone E.R. Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease. J. Neurosci. Res. 2009, 87:1748-1759.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 1748-1759
    • Galbiati, F.1    Givogri, M.I.2    Cantuti, L.3    Lopez Rosas, A.4    Cao, H.5    van Breemen, R.6    Bongarzone, E.R.7
  • 11
    • 43549092043 scopus 로고    scopus 로고
    • The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease
    • Giri S., Khan M., Nath N., Singh I., Singh A.K. The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease. J. Neurochem. 2008, 105:1820-1833.
    • (2008) J. Neurochem. , vol.105 , pp. 1820-1833
    • Giri, S.1    Khan, M.2    Nath, N.3    Singh, I.4    Singh, A.K.5
  • 12
    • 0141767087 scopus 로고    scopus 로고
    • Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line
    • Haq E., Giri S., Singh I., Singh A.K. Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line. J. Neurochem. 2003, 86:1428-1440.
    • (2003) J. Neurochem. , vol.86 , pp. 1428-1440
    • Haq, E.1    Giri, S.2    Singh, I.3    Singh, A.K.4
  • 13
    • 33645104535 scopus 로고    scopus 로고
    • Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease
    • Haq E., Contreras M.A., Giri S., Singh I., Singh A.K. Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease. Biochem. Biophys. Res. Commun. 2006, 343:229-238.
    • (2006) Biochem. Biophys. Res. Commun. , vol.343 , pp. 229-238
    • Haq, E.1    Contreras, M.A.2    Giri, S.3    Singh, I.4    Singh, A.K.5
  • 14
    • 79956023383 scopus 로고    scopus 로고
    • Combination therapies for lysosomal storage disease: is the whole greater than the sum of its parts?
    • Hawkins-Salsbury J.A., Reddy A.S., Sands M.S. Combination therapies for lysosomal storage disease: is the whole greater than the sum of its parts?. Hum. Mol. Genet. 2011, 20:R54-R60.
    • (2011) Hum. Mol. Genet. , vol.20
    • Hawkins-Salsbury, J.A.1    Reddy, A.S.2    Sands, M.S.3
  • 15
    • 0021339782 scopus 로고
    • Progressive accumulation of toxic metabolite in a genetic leukodystrophy
    • Igisu H., Suzuki K. Progressive accumulation of toxic metabolite in a genetic leukodystrophy. Science 1984, 224:753-755.
    • (1984) Science , vol.224 , pp. 753-755
    • Igisu, H.1    Suzuki, K.2
  • 16
    • 21844461354 scopus 로고    scopus 로고
    • Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease
    • Khan M., Haq E., Giri S., Singh I., Singh A.K. Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease. J. Neurosci. Res. 2005, 80:845-854.
    • (2005) J. Neurosci. Res. , vol.80 , pp. 845-854
    • Khan, M.1    Haq, E.2    Giri, S.3    Singh, I.4    Singh, A.K.5
  • 17
    • 0019274883 scopus 로고
    • The Twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease)
    • Kobayashi T., Yamanaka T., Jacobs J.M., Teixeira F., Suzuki K. The Twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease). Brain Res. 1980, 202:479-483.
    • (1980) Brain Res. , vol.202 , pp. 479-483
    • Kobayashi, T.1    Yamanaka, T.2    Jacobs, J.M.3    Teixeira, F.4    Suzuki, K.5
  • 18
    • 79952406068 scopus 로고    scopus 로고
    • Macrophages counteract demyelination in a mouse model of globoid cell leukodystrophy
    • Kondo Y., Adams J.M., Vanier M.T., Duncan I.D. Macrophages counteract demyelination in a mouse model of globoid cell leukodystrophy. J. Neurosci. 2011, 31:3610-3624.
    • (2011) J. Neurosci. , vol.31 , pp. 3610-3624
    • Kondo, Y.1    Adams, J.M.2    Vanier, M.T.3    Duncan, I.D.4
  • 19
    • 33845983322 scopus 로고    scopus 로고
    • Central nervous system-directed AAV2/5-mediated gene therapy synergizes with bone marrow transplantation in the murine model of globoid-cell leukodystrophy
    • Lin D., Donsante A., Macauley S., Levy B., Vogler C., Sands M.S. Central nervous system-directed AAV2/5-mediated gene therapy synergizes with bone marrow transplantation in the murine model of globoid-cell leukodystrophy. Mol. Ther. 2007, 15:44-52.
    • (2007) Mol. Ther. , vol.15 , pp. 44-52
    • Lin, D.1    Donsante, A.2    Macauley, S.3    Levy, B.4    Vogler, C.5    Sands, M.S.6
  • 20
    • 80054910077 scopus 로고    scopus 로고
    • The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis
    • Macauley S.L., Pekny M., Sands M.S. The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis. J. Neurosci. 2011, 31:15575-15585.
    • (2011) J. Neurosci. , vol.31 , pp. 15575-15585
    • Macauley, S.L.1    Pekny, M.2    Sands, M.S.3
  • 21
    • 84862773359 scopus 로고    scopus 로고
    • Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis
    • Macauley S.L., Roberts M.S., Wong A.M., McSloy F., Reddy A.S., Cooper J.D., Sands M.S. Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis. Ann. Neurol. 2012, 71:797-804.
    • (2012) Ann. Neurol. , vol.71 , pp. 797-804
    • Macauley, S.L.1    Roberts, M.S.2    Wong, A.M.3    McSloy, F.4    Reddy, A.S.5    Cooper, J.D.6    Sands, M.S.7
  • 22
    • 0029154990 scopus 로고
    • Uptake and distribution of N-acetylcysteine in mice: tissue-specific effects on glutathione concentrations
    • McLellan L.I., Lewis A.D., Hall D.J., Ansell J.D., Wolf C.R. Uptake and distribution of N-acetylcysteine in mice: tissue-specific effects on glutathione concentrations. Carcinogenesis 1995, 16:2099-2106.
    • (1995) Carcinogenesis , vol.16 , pp. 2099-2106
    • McLellan, L.I.1    Lewis, A.D.2    Hall, D.J.3    Ansell, J.D.4    Wolf, C.R.5
  • 24
    • 0033967664 scopus 로고    scopus 로고
    • In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain
    • Pocernich C.B., La Fontaine M., Butterfield D.A. In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochem. Int. 2000, 36:185-191.
    • (2000) Neurochem. Int. , vol.36 , pp. 185-191
    • Pocernich, C.B.1    La Fontaine, M.2    Butterfield, D.A.3
  • 25
    • 79960066219 scopus 로고    scopus 로고
    • Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy
    • Reddy A.S., Kim J.H., Hawkins-Salsbury J.A., Macauley S.L., Tracy E.T., Vogler C.A., Han X., Song S.K., Wozniak D.F., Fowler S.C., Klein R.S., Sands M.S. Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy. J. Neurosci. 2011, 31:9945-9957.
    • (2011) J. Neurosci. , vol.31 , pp. 9945-9957
    • Reddy, A.S.1    Kim, J.H.2    Hawkins-Salsbury, J.A.3    Macauley, S.L.4    Tracy, E.T.5    Vogler, C.A.6    Han, X.7    Song, S.K.8    Wozniak, D.F.9    Fowler, S.C.10    Klein, R.S.11    Sands, M.S.12
  • 28
    • 0033020597 scopus 로고    scopus 로고
    • Percutaneous intravenous injection in neonatal mice
    • Sands M.S., Barker J.E. Percutaneous intravenous injection in neonatal mice. Lab. Anim. Sci. 1999, 49:328-330.
    • (1999) Lab. Anim. Sci. , vol.49 , pp. 328-330
    • Sands, M.S.1    Barker, J.E.2
  • 29
    • 0031932297 scopus 로고    scopus 로고
    • Twenty five years of the "psychosine hypothesis": a personal perspective of its history and present status
    • Suzuki K. Twenty five years of the "psychosine hypothesis": a personal perspective of its history and present status. Neurochem. Res. 1998, 23:251-259.
    • (1998) Neurochem. Res. , vol.23 , pp. 251-259
    • Suzuki, K.1
  • 30
    • 0000708535 scopus 로고
    • Physiological activity of psychosine
    • Taketomi T., Nishimura K. Physiological activity of psychosine. Jpn. J. Exp. Med. 1964, 34:255-265.
    • (1964) Jpn. J. Exp. Med. , vol.34 , pp. 255-265
    • Taketomi, T.1    Nishimura, K.2
  • 31
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues
    • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 1969, 27:502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 33
    • 18744412645 scopus 로고    scopus 로고
    • Plasma infusions into porcine cerebral white matter induce early edema, oxidative stress, pro-inflammatory cytokine gene expression and DNA fragmentation: implications for white matter injury with increased blood-brain-barrier permeability
    • Wagner K.R., Dean C., Beiler S., Bryan D.W., Packard B.A., Smulian A.G., Linke M.J., de Courten-Myers G.M. Plasma infusions into porcine cerebral white matter induce early edema, oxidative stress, pro-inflammatory cytokine gene expression and DNA fragmentation: implications for white matter injury with increased blood-brain-barrier permeability. Curr. Neurovasc. Res. 2005, 2:149-155.
    • (2005) Curr. Neurovasc. Res. , vol.2 , pp. 149-155
    • Wagner, K.R.1    Dean, C.2    Beiler, S.3    Bryan, D.W.4    Packard, B.A.5    Smulian, A.G.6    Linke, M.J.7    de Courten-Myers, G.M.8
  • 34
    • 0002054185 scopus 로고    scopus 로고
    • Galactosylceramide lipidosis: globoid cell leukodystrophy (Krabbe disease)
    • McGraw-Hill Medical Publishing Division, New York, C. Scriver, A. Beaudet, W. Sly, D. Valle, B. Childs, K. Kinzler, B. Vogelstein (Eds.)
    • Wenger D., Suzuki K., Suzuki Y. Galactosylceramide lipidosis: globoid cell leukodystrophy (Krabbe disease). The Metabolic and Molecular Basis of Disease 2001, 2669-3694. McGraw-Hill Medical Publishing Division, New York. C. Scriver, A. Beaudet, W. Sly, D. Valle, B. Childs, K. Kinzler, B. Vogelstein (Eds.).
    • (2001) The Metabolic and Molecular Basis of Disease , pp. 2669-3694
    • Wenger, D.1    Suzuki, K.2    Suzuki, Y.3
  • 35
  • 36
    • 1642404670 scopus 로고    scopus 로고
    • Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation
    • Zaka M., Wenger D.A. Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation. Neurosci. Lett. 2004, 358:205-209.
    • (2004) Neurosci. Lett. , vol.358 , pp. 205-209
    • Zaka, M.1    Wenger, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.