Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy

Nature Medicine

Volumn 16, Issue 8, 2010, Pages 869-871

  Viscomi, Carlo ^a   Burlina, Alberto B ^b   Dweikat, Imad ^c   Savoiardo, Mario ^a   Lamperti, Costanza ^a   Hildebrandt, Tatjana ^d   Tiranti, Valeria ^a   Zeviani, Massimo ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

^b UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^c Al Makassed Islamic Charitable Society Hospital   (Israel)

^d LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ETHE1 PROTEIN; MEMBRANE PROTEIN; METRONIDAZOLE; RANITIDINE; SULFIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DISEASE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ETHYLMALONIC ENCEPHALOPATHY; FEMALE; GASTROESOPHAGEAL REFLUX; GENE MUTATION; HUMAN; INFANT; LIFESPAN; MALE; MOUSE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; TREATMENT OUTCOME;

ACETYLCYSTEINE; ADMINISTRATION, ORAL; ANIMALS; ANTI-INFECTIVE AGENTS; BRAIN DISEASES, METABOLIC, INBORN; CHILD, PRESCHOOL; DIOXYGENASES; DRUG COMBINATIONS; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; INFANT; MALE; MALONATES; METRONIDAZOLE; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; TREATMENT OUTCOME;

MUS;

EID: 77955427368     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2188     Document Type: Article

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