Silencing of GPNMB by siRNA inhibits the formation of melanosomes in melanocytes in a MITF-independent fashion

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Zhang, Ping ^a,b   Liu, Wei ^a,b   Zhu, Cansheng ^c   Yuan, Xiaoying ^a   Li, Dongguang ^a   Gu, Weijie ^a   Ma, Huimin ^a   Xie, Xin ^d   Gao, Tianwen ^b  

^a AIR FORCE GENERAL HOSPITAL   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c Shaanxi Provincial Institute for Endemic Disease Control   (China)

^d NORTHWEST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLYCOPROTEIN GP 100; GLYCOPROTEIN NONMETASTATIC MELANOMA PROTEIN B; MELANOCYTE PROTEIN PMEL 17; MEMBRANE PROTEIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; OCULAR ALBINISM TYPE 1 PROTEIN; SMALL INTERFERING RNA; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL COUNT; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MELANOCYTE; MELANOSOME; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSPORT; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET B RADIATION; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; DNA PRIMERS; EYE PROTEINS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; MELANOCYTES; MELANOSOMES; MEMBRANE GLYCOPROTEINS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MONOPHENOL MONOOXYGENASE; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRYPSIN; ULTRAVIOLET RAYS;

EID: 84865048544     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042955     Document Type: Article

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