Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β

Journal of Biological Chemistry

Volumn 287, Issue 22, 2012, Pages 17996-18004

  Pierrat, Marie Jeanne ^a   Marsaud, Véronique ^a   Mauviel, Alain ^a   Javelaud, Delphine ^a  

^a INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGONISTIC ACTIVITY; CELL TRANSFECTION; CHROMATIN IMMUNOPRECIPITATION; COMPLEX ROLES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ELEMENT-BINDING PROTEINS; GENE REPRESSION; HEDGEHOG SIGNALING; INVASIVENESS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MELANOMA CELLS; MOLECULAR MECHANISM; PROMOTER ACTIVITIES; PROTEIN KINASE A; SITE DIRECTED MUTAGENESIS; TRANSCRIPTIONAL REPRESSION; TRANSCRIPTIONAL TARGETS; TRANSFORMING GROWTH FACTORS;

BINDING SITES; DERMATOLOGY; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; GENES; ONCOLOGY; TRANSCRIPTION;

TRANSCRIPTION FACTORS;

CIS ACTING ELEMENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI2; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BINDING SITE; CANCER GROWTH; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE REPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MELANOMA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

BASE SEQUENCE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DISEASE PROGRESSION; DNA PRIMERS; DNA, NEOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MELANOMA; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

ERINACEIDAE;

EID: 84861547496     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.358341     Document Type: Article

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