Tyrosine residues mediate fibril formation in a dynamic light chain dimer interface

Journal of Biological Chemistry

Volumn 287, Issue 33, 2012, Pages 27997-28006

  DiCostanzo, Ara Celi ^a   Thompson, James R ^a   Peterson, Francis C ^b   Volkman, Brian F ^b   Ramirez Alvarado, Marina ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRIL; AMYLOID FORMATION; CONFORMATIONAL HETEROGENEITY; DIMER INTERFACE; FIBRIL FORMATION; IMMUNOGLOBULIN LIGHT CHAINS; LIGHT CHAIN; NMR STUDIES; ORGAN FAILURE; PROTEIN MISFOLDING; TYROSINE RESIDUES;

AMINO ACIDS; GLYCOPROTEINS; MONOCLONAL ANTIBODIES; PROTEINS;

ALUMINUM;

AMYLOID; IMMUNOGLOBULIN LIGHT CHAIN; PHENYLALANINE; TYROSINE;

AMINO ACID SUBSTITUTION; AMYLOIDOSIS; ARTICLE; CIRCULAR DICHROISM; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; IONIZATION; LIGHT CHAIN AMYLOIDOSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMYLOID; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN LIGHT CHAINS; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN MULTIMERIZATION; TYROSINE;

EID: 84865034948     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.362921     Document Type: Article

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