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Volumn 33, Issue 30, 2012, Pages 7540-7546

Physiological pathway of human cell damage induced by genotoxic crystalline silica nanoparticles

Author keywords

DNA damage; Mitochondrion multiplication; P53; ROS generation; Silica nanoparticles

Indexed keywords

ANTI-OXIDATION; BIOLOGICAL PATHWAYS; CATASTROPHIC EFFECTS; CELL DAMAGE; CELL PHYSIOLOGY; CRYSTALLINE SILICA; DNA DAMAGES; DNA FRAGMENTATION; GENOTOXIC; GENOTOXIC EFFECTS; HUMAN CELLS; P53; P53 GENE; REACTIVE OXYGEN SPECIES; ROS GENERATION; SILICA NANOPARTICLES;

EID: 84865026006     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.06.073     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 0028947494 scopus 로고
    • Crystalline silica-risks and policy
    • Hardy T.S., Weill H. Crystalline silica-risks and policy. Environ Health Perspect 1995, 103:152-155.
    • (1995) Environ Health Perspect , vol.103 , pp. 152-155
    • Hardy, T.S.1    Weill, H.2
  • 2
    • 33845218637 scopus 로고    scopus 로고
    • In vitro toxicity of silica nanoparticles in human lung cancer cells
    • Lin W.S., Huang Y.W., Zhou X.D., Ma Y.F. In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol Appl Pharmacol 2006, 217:252-259.
    • (2006) Toxicol Appl Pharmacol , vol.217 , pp. 252-259
    • Lin, W.S.1    Huang, Y.W.2    Zhou, X.D.3    Ma, Y.F.4
  • 3
    • 4544255267 scopus 로고    scopus 로고
    • Biological effects of ultrafine model particles in human macrophages and epithelial cells in mono- and co-culture
    • Wottrich R., Diabate S., Krug H.F. Biological effects of ultrafine model particles in human macrophages and epithelial cells in mono- and co-culture. Int J Hyg Environ Health 2004, 207:353-361.
    • (2004) Int J Hyg Environ Health , vol.207 , pp. 353-361
    • Wottrich, R.1    Diabate, S.2    Krug, H.F.3
  • 5
    • 0030211133 scopus 로고    scopus 로고
    • Time course of chemotactic factor generation and neutrophil recruitment in the lungs of dust-exposed rats
    • Yuen I.S., Hartsky M.A., Snajdr S.I., Warheit D.B. Time course of chemotactic factor generation and neutrophil recruitment in the lungs of dust-exposed rats. Am J Respir Cell Mol Biol 1996, 15:268-274.
    • (1996) Am J Respir Cell Mol Biol , vol.15 , pp. 268-274
    • Yuen, I.S.1    Hartsky, M.A.2    Snajdr, S.I.3    Warheit, D.B.4
  • 6
    • 0030981092 scopus 로고    scopus 로고
    • Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer
    • McLaughlin J.K., Chow W.H., Levy L.S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol Environ Health 1997, 50:553-566.
    • (1997) J Toxicol Environ Health , vol.50 , pp. 553-566
    • McLaughlin, J.K.1    Chow, W.H.2    Levy, L.S.3
  • 7
    • 0030813771 scopus 로고    scopus 로고
    • Silica, some silicates, coal dust and para-amid fibrils
    • International Agency for Research on Cancer (IARC)
    • International Agency for Research on Cancer (IARC) Silica, some silicates, coal dust and para-amid fibrils. IARC Monogr Eval Carcinog Risks Hum 1997, 68:337-406.
    • (1997) IARC Monogr Eval Carcinog Risks Hum , vol.68 , pp. 337-406
  • 8
    • 0037384107 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease due to occupational exposure to silica dust: a review of epidemiological and pathological evidence
    • Hnizdo E., Vallyathan V. Chronic obstructive pulmonary disease due to occupational exposure to silica dust: a review of epidemiological and pathological evidence. Occup Environ Med 2003, 60:237-243.
    • (2003) Occup Environ Med , vol.60 , pp. 237-243
    • Hnizdo, E.1    Vallyathan, V.2
  • 9
    • 33645508531 scopus 로고    scopus 로고
    • Chronic inflammation: a common and important factor in the pathogenesis of neoplasia
    • Schottenfeld D., Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J Clin 2006, 56:69-83.
    • (2006) CA Cancer J Clin , vol.56 , pp. 69-83
    • Schottenfeld, D.1    Beebe-Dimmer, J.2
  • 10
    • 0032698065 scopus 로고    scopus 로고
    • Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK
    • Ding M., Shi X.L., Dong Z.G., Chen F., Lu Y.J., Castranova V., et al. Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. J Biol Chem 1999, 274:30611-30616.
    • (1999) J Biol Chem , vol.274 , pp. 30611-30616
    • Ding, M.1    Shi, X.L.2    Dong, Z.G.3    Chen, F.4    Lu, Y.J.5    Castranova, V.6
  • 11
    • 33947360667 scopus 로고    scopus 로고
    • In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line
    • Chang J.S., Chang K.L.B., Hwang D.F., Kong Z.L. In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line. Environ Sci Technol 2007, 41:2064-2068.
    • (2007) Environ Sci Technol , vol.41 , pp. 2064-2068
    • Chang, J.S.1    Chang, K.L.B.2    Hwang, D.F.3    Kong, Z.L.4
  • 12
    • 20444406055 scopus 로고
    • Controlled growth of monodisperse silica spheres in micron size range
    • Stober W., Fink A., Bohn E. Controlled growth of monodisperse silica spheres in micron size range. J Colloid Interface Sci 1968, 26:62-69.
    • (1968) J Colloid Interface Sci , vol.26 , pp. 62-69
    • Stober, W.1    Fink, A.2    Bohn, E.3
  • 13
    • 80051585527 scopus 로고    scopus 로고
    • Cellular uptake, evolution, and excretion of silica nanoparticles in human cells
    • Chu Z.Q., Huang Y.J., Tao Q., Li Q. Cellular uptake, evolution, and excretion of silica nanoparticles in human cells. Nanoscale 2011, 3:3291-3299.
    • (2011) Nanoscale , vol.3 , pp. 3291-3299
    • Chu, Z.Q.1    Huang, Y.J.2    Tao, Q.3    Li, Q.4
  • 14
    • 0035545829 scopus 로고    scopus 로고
    • Resveratrol induces colon tumor cell apoptosis independently of p53 and preceded by epithelial differentiation, mitochondrial proliferation and membrane potential collapse
    • Mahyar-Roemer M., Katsen A., Mestres P., Roemer K. Resveratrol induces colon tumor cell apoptosis independently of p53 and preceded by epithelial differentiation, mitochondrial proliferation and membrane potential collapse. Int J Cancer 2001, 94:615-622.
    • (2001) Int J Cancer , vol.94 , pp. 615-622
    • Mahyar-Roemer, M.1    Katsen, A.2    Mestres, P.3    Roemer, K.4
  • 15
    • 1842735367 scopus 로고    scopus 로고
    • Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines
    • Kuhn H., Kopff C., Konrad J., Riedel A., Gessner C., Wirtz H. Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines. Lung Cancer 2004, 44:167-174.
    • (2004) Lung Cancer , vol.44 , pp. 167-174
    • Kuhn, H.1    Kopff, C.2    Konrad, J.3    Riedel, A.4    Gessner, C.5    Wirtz, H.6
  • 16
    • 0033389119 scopus 로고    scopus 로고
    • Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts
    • Wiesner R.J., Hornung T.V., Garman J.D., Clayton D.A., O'Gorman E., Wallimann T. Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts. J Bioenerg Biomembr 1999, 31:559-567.
    • (1999) J Bioenerg Biomembr , vol.31 , pp. 559-567
    • Wiesner, R.J.1    Hornung, T.V.2    Garman, J.D.3    Clayton, D.A.4    O'Gorman, E.5    Wallimann, T.6
  • 17
    • 0030792850 scopus 로고    scopus 로고
    • Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line
    • Mancini M., Anderson B.O., Caldwell E., Sedghinasab M., Paty P.B., Hockenbery D.M. Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line. J Cell Biol 1997, 138:449-469.
    • (1997) J Cell Biol , vol.138 , pp. 449-469
    • Mancini, M.1    Anderson, B.O.2    Caldwell, E.3    Sedghinasab, M.4    Paty, P.B.5    Hockenbery, D.M.6
  • 18
    • 0034062788 scopus 로고    scopus 로고
    • Involvement of oxidative stress in crystalline silica-induced cytotoxicity and genotoxicity in rat alveolar macrophages
    • Zhang Z., Shen H.M., Zhang Q.F., Ong C.N. Involvement of oxidative stress in crystalline silica-induced cytotoxicity and genotoxicity in rat alveolar macrophages. Environ Res 2000, 82:245-252.
    • (2000) Environ Res , vol.82 , pp. 245-252
    • Zhang, Z.1    Shen, H.M.2    Zhang, Q.F.3    Ong, C.N.4
  • 19
    • 0035937720 scopus 로고    scopus 로고
    • Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells
    • Ding M., Shi X.L., Lu Y.J., Huang C.S., Leonard S., Roberts J., et al. Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells. J Biol Chem 2001, 276:9108-9114.
    • (2001) J Biol Chem , vol.276 , pp. 9108-9114
    • Ding, M.1    Shi, X.L.2    Lu, Y.J.3    Huang, C.S.4    Leonard, S.5    Roberts, J.6
  • 20
    • 0034669120 scopus 로고    scopus 로고
    • Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages
    • Kang J.L., Pack I.S., Hong S.M., Lee H.S., Castranova V. Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages. Toxicol Appl Pharmacol 2000, 169:59-65.
    • (2000) Toxicol Appl Pharmacol , vol.169 , pp. 59-65
    • Kang, J.L.1    Pack, I.S.2    Hong, S.M.3    Lee, H.S.4    Castranova, V.5
  • 21
    • 0035266157 scopus 로고    scopus 로고
    • Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress
    • Shukla A., Timblin C.R., Hubbard A.K., Bravman J., Mossman B.T. Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress. Cancer Res 2001, 61:1791-1795.
    • (2001) Cancer Res , vol.61 , pp. 1791-1795
    • Shukla, A.1    Timblin, C.R.2    Hubbard, A.K.3    Bravman, J.4    Mossman, B.T.5
  • 22
    • 0019083215 scopus 로고
    • Generation of superoxide anion by the NADH dehydrogenase of bovine heart-mitochondria
    • Turrens J.F., Boveris A. Generation of superoxide anion by the NADH dehydrogenase of bovine heart-mitochondria. Biochem J 1980, 191:421-427.
    • (1980) Biochem J , vol.191 , pp. 421-427
    • Turrens, J.F.1    Boveris, A.2
  • 23
    • 0030872907 scopus 로고    scopus 로고
    • Selective targeting of bioactive compounds to mitochondria
    • Murphy M.P. Selective targeting of bioactive compounds to mitochondria. Trends Biotechnol 1997, 15:326-330.
    • (1997) Trends Biotechnol , vol.15 , pp. 326-330
    • Murphy, M.P.1
  • 24
    • 0035970721 scopus 로고    scopus 로고
    • Nuclear and mitochondrial apoptotic pathways of p53
    • Moll U.M., Zaika A. Nuclear and mitochondrial apoptotic pathways of p53. FEBS Lett 2001, 493:65-69.
    • (2001) FEBS Lett , vol.493 , pp. 65-69
    • Moll, U.M.1    Zaika, A.2
  • 25
    • 0030852948 scopus 로고    scopus 로고
    • Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction
    • Liu Y.B., Peterson D.A., Kimura H., Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 1997, 69:581-593.
    • (1997) J Neurochem , vol.69 , pp. 581-593
    • Liu, Y.B.1    Peterson, D.A.2    Kimura, H.3    Schubert, D.4
  • 26
    • 65449178474 scopus 로고    scopus 로고
    • Size-dependent cytotoxicity of monodisperse silica nanoparticles in human Endothelial cells
    • Napierska D., Thomassen L.C.J., Rabolli V., Lison D., Gonzalez L., Kirsch-Volders M., et al. Size-dependent cytotoxicity of monodisperse silica nanoparticles in human Endothelial cells. Small 2009, 5:846-853.
    • (2009) Small , vol.5 , pp. 846-853
    • Napierska, D.1    Thomassen, L.C.J.2    Rabolli, V.3    Lison, D.4    Gonzalez, L.5    Kirsch-Volders, M.6
  • 27
    • 0031840305 scopus 로고    scopus 로고
    • Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa
    • Lopes S., Jurisicova A., Sun J.G., Casper R.F. Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa. Hum Reprod 1998, 13:896-900.
    • (1998) Hum Reprod , vol.13 , pp. 896-900
    • Lopes, S.1    Jurisicova, A.2    Sun, J.G.3    Casper, R.F.4
  • 28
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke T.M., Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunol Today 1994, 15:7-10.
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 29
    • 0028095981 scopus 로고
    • Oxidative stress induces apoptosis in embryonic cortical-neurons
    • Ratan R.R., Murphy T.H., Baraban J.M. Oxidative stress induces apoptosis in embryonic cortical-neurons. J Neurochem 1994, 62:376-379.
    • (1994) J Neurochem , vol.62 , pp. 376-379
    • Ratan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 30
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 32
    • 33845613217 scopus 로고    scopus 로고
    • Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristics
    • Warheit D.B., Webb T.R., Colvin V.L., Reed K.L., Sayes C.R. Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristics. Toxicol Sci 2007, 95:270-280.
    • (2007) Toxicol Sci , vol.95 , pp. 270-280
    • Warheit, D.B.1    Webb, T.R.2    Colvin, V.L.3    Reed, K.L.4    Sayes, C.R.5
  • 33
    • 0038359740 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
    • Fubini B., Hubbard A. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 2003, 34:1507-1516.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1507-1516
    • Fubini, B.1    Hubbard, A.2
  • 34
    • 34250217766 scopus 로고    scopus 로고
    • Exposure of engineered nanoparticles to human lung epithelial cells: Influence of chemical composition and catalytic activity on oxidative stress
    • Limbach L.K., Wick P., Manser P., Grass R.N., Bruinink A., Stark W.J. Exposure of engineered nanoparticles to human lung epithelial cells: Influence of chemical composition and catalytic activity on oxidative stress. Environ Sci Technol 2007, 41:4158-4163.
    • (2007) Environ Sci Technol , vol.41 , pp. 4158-4163
    • Limbach, L.K.1    Wick, P.2    Manser, P.3    Grass, R.N.4    Bruinink, A.5    Stark, W.J.6
  • 35
    • 11244344381 scopus 로고    scopus 로고
    • P53: Traffic cop at the crossroads of DNA repair and recombination
    • Sengupta S., Harris C.C. p53: Traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 2005, 6:44-55.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 44-55
    • Sengupta, S.1    Harris, C.C.2


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