메뉴 건너뛰기




Volumn 41, Issue 3, 2012, Pages 995-1004

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

Author keywords

Metastasis; Ras; RasGRF1; Rhabdomyosarcoma

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN P42; PROTEIN P44; SHORT HAIRPIN RNA; SOMATOMEDIN B; STROMAL CELL DERIVED FACTOR 1;

EID: 84864982660     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1536     Document Type: Article
Times cited : (17)

References (50)
  • 1
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • DOI 10.1038/ng0293-113
    • Barr FG, Galili N, Holick J, Biegel JA, Rovera G and Emanuel BS: Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 3: 113-117, 1993. (Pubitemid 23079791)
    • (1993) Nature Genetics , vol.3 , Issue.2 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuell, B.S.6
  • 2
    • 0034899529 scopus 로고    scopus 로고
    • Proliferative and apoptotic differences between alveolar rhabdomyosarcoma subtypes: A comparative study of tumors containing PAX-3-FKHR or PAX-7-FKHR gene fusions
    • DOI 10.1002/mpo.1174
    • Collins MH, Zhao H, Womer RB and Barr FG: Proliferative and apoptotic differences between alveolar rhabdomyosarcoma subtypes: a comparative study of tumors containing PAX3-FKHR or PAX7-FKHR gene fusions. Med Pediatr Oncol 37: 83-89, 2001. (Pubitemid 32738067)
    • (2001) Medical and Pediatric Oncology , vol.37 , Issue.2 , pp. 83-89
    • Collins, M.H.1    Zhao, H.2    Womer, R.B.3    Barr, F.G.4
  • 3
    • 0023257034 scopus 로고
    • Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma
    • Hazelton BJ, Houghton JA, Parham DM, et al: Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma. Cancer Res 47: 4501-4507, 1987. (Pubitemid 17128155)
    • (1987) Cancer Research , vol.47 , Issue.16 , pp. 4501-4507
    • Hazelton, B.J.1    Houghton, J.A.2    Parham, D.M.3
  • 4
    • 0032455878 scopus 로고    scopus 로고
    • PAX3-FKHR and PAX7-FKHR gene fusions in rhabdomyosarcoma [2]
    • DOI 10.1097/00043426-199809000-00027
    • Kelly KM, Womer RB and Barr FG: PAX3-FKHR and PAX7-FKHR gene fusions in rhabdomyosarcoma. J Pediatr Hematol Oncol 20: 517-518, 1998. (Pubitemid 29133216)
    • (1998) Journal of Pediatric Hematology/Oncology , vol.20 , Issue.5 , pp. 517-518
    • Kelly, K.M.1    Womer, R.B.2    Barr, F.G.3
  • 8
    • 67349218119 scopus 로고    scopus 로고
    • Alveolar rhabdomyosarcoma: Is the cell of origin a mesenchymal stem cell?
    • Charytonowicz E, Cordon-Cardo C, Matushansky I and Ziman M: Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell? Cancer Lett 279: 126-136, 2009.
    • (2009) Cancer Lett , vol.279 , pp. 126-136
    • Charytonowicz, E.1    Cordon-Cardo, C.2    Matushansky, I.3    Ziman, M.4
  • 9
    • 0034665975 scopus 로고    scopus 로고
    • Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma
    • Hahn H, Wojnowski L, Specht K, et al: Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J Biol Chem 275: 28341-28344, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 28341-28344
    • Hahn, H.1    Wojnowski, L.2    Specht, K.3
  • 10
    • 63449142234 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors
    • Makawita S, Ho M, Durbin AD, Thorner PS, Malkin D and Somers GR: Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors. Pediatr Dev Pathol 12: 127-135, 2009.
    • (2009) Pediatr Dev Pathol , vol.12 , pp. 127-135
    • Makawita, S.1    Ho, M.2    Durbin, A.D.3    Thorner, P.S.4    Malkin, D.5    Somers, G.R.6
  • 12
    • 0032189704 scopus 로고    scopus 로고
    • Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma
    • Wang W, Kumar P, Epstein J, Helman L, Moore JV and Kumar S: Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma. Cancer Res 58: 4426-4433, 1998. (Pubitemid 28450047)
    • (1998) Cancer Research , vol.58 , Issue.19 , pp. 4426-4433
    • Wang, W.1    Kumar, P.2    Wang, W.3    Epstein, J.4    Helman, L.5    Moore, J.V.6    Kumar, S.7
  • 13
    • 57149093809 scopus 로고    scopus 로고
    • Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma
    • Naini S, Etheridge KT, Adam SJ, et al: Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma. Cancer Res 68: 9583-9588, 2008.
    • (2008) Cancer Res , vol.68 , pp. 9583-9588
    • Naini, S.1    Etheridge, K.T.2    Adam, S.J.3
  • 14
    • 0032722971 scopus 로고    scopus 로고
    • CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways
    • DOI 10.1016/S0014-5793(99)01374-5, PII S0014579399013745
    • Innocenti M, Zippel R, Brambilla R and Sturani E: CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways. FEBS Lett 460: 357-362, 1999. (Pubitemid 29495969)
    • (1999) FEBS Letters , vol.460 , Issue.2 , pp. 357-362
    • Innocenti, M.1    Zippel, R.2    Brambilla, R.3    Sturani, E.4
  • 15
    • 62149141379 scopus 로고    scopus 로고
    • Identification of novel RasGRF1 interacting partners by large-scale proteomic analysis
    • Lavagni P, Indrigo M, Colombo G, et al: Identification of novel RasGRF1 interacting partners by large-scale proteomic analysis. J Mol Neurosci 37: 212-224, 2009.
    • (2009) J Mol Neurosci , vol.37 , pp. 212-224
    • Lavagni, P.1    Indrigo, M.2    Colombo, G.3
  • 16
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
    • DOI 10.1038/nrm1587
    • Rossman KL, Der CJ and Sondek J: GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6: 167-180, 2005. (Pubitemid 40215811)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.2 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 18
    • 34247134489 scopus 로고    scopus 로고
    • Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1
    • DOI 10.1097/IOP.0b013e318032af94, PII 0000234120070300000016
    • Shome D, Honavar SG, Reddy VA and Vemuganti GK: Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1. Ophthal Plast Reconstr Surg 23: 147-148, 2007. (Pubitemid 46596609)
    • (2007) Ophthalmic Plastic and Reconstructive Surgery , vol.23 , Issue.2 , pp. 147-148
    • Shome, D.1    Honavar, S.G.2    Reddy, V.A.P.3    Vemuganti, G.K.4
  • 19
    • 0028793138 scopus 로고
    • Association of childhood rhabdomyosarcoma with neurofibromatosis type I and birth defects
    • Yang P, Grufferman S, Khoury MJ, et al: Association of childhood rhabdomyosarcoma with neurofibromatosis type I and birth defects. Genet Epidemiol 12: 467-474, 1995.
    • (1995) Genet Epidemiol , vol.12 , pp. 467-474
    • Yang, P.1    Grufferman, S.2    Khoury, M.J.3
  • 21
    • 0029027050 scopus 로고
    • Vaginal rhabdomyosarcoma in a patient with Noonan syndrome
    • Khan S, McDowell H, Upadhyaya M and Fryer A: Vaginal rhabdomyosarcoma in a patient with Noonan syndrome. J Med Genet 32: 743-745, 1995.
    • (1995) J Med Genet , vol.32 , pp. 743-745
    • Khan, S.1    McDowell, H.2    Upadhyaya, M.3    Fryer, A.4
  • 22
    • 0037082975 scopus 로고    scopus 로고
    • Five additional Costello syndrome patients with rhabdomyosarcoma: Proposal for a tumor screening protocol
    • Gripp KW, Scott CI Jr, Nicholson L, et al: Five additional Costello syndrome patients with rhabdomyosarcoma: proposal for a tumor screening protocol. Am J Med Genet 108: 80-87, 2002.
    • (2002) Am J Med Genet , vol.108 , pp. 80-87
    • Gripp, K.W.1    Scott Jr., C.I.2    Nicholson, L.3
  • 23
    • 0032966589 scopus 로고    scopus 로고
    • Costello syndrome and rhabdomyosarcoma
    • Feingold M: Costello syndrome and rhabdomyosarcoma. J Med Genet 36: 582-583, 1999.
    • (1999) J Med Genet , vol.36 , pp. 582-583
    • Feingold, M.1
  • 25
    • 68649121646 scopus 로고    scopus 로고
    • The RASopathies: Developmental syndromes of Ras/MAPK pathway dysregulation
    • Tidyman WE and Rauen KA: The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation. Curr Opin Genet Dev 19: 230-236, 2009.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 230-236
    • Tidyman, W.E.1    Rauen, K.A.2
  • 26
    • 76249092163 scopus 로고    scopus 로고
    • Muscling in: Uncovering the origins of rhabdomyosarcoma
    • Hettmer S and Wagers AJ: Muscling in: uncovering the origins of rhabdomyosarcoma. Nat Med 16: 171-173, 2010.
    • (2010) Nat Med , vol.16 , pp. 171-173
    • Hettmer, S.1    Wagers, A.J.2
  • 27
    • 70450260628 scopus 로고    scopus 로고
    • Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells
    • Shin DM, Zuba-Surma EK, Wu W, et al: Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells. Leukemia 23: 2042-2051, 2009.
    • (2009) Leukemia , vol.23 , pp. 2042-2051
    • Shin, D.M.1    Zuba-Surma, E.K.2    Wu, W.3
  • 28
    • 0024388736 scopus 로고
    • Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction
    • Stratton MR, Fisher C, Gusterson BA and Cooper CS: Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction. Cancer Res 49: 6324-6327, 1989. (Pubitemid 20000931)
    • (1989) Cancer Research , vol.49 , Issue.22 , pp. 6324-6327
    • Stratton, M.R.1    Fisher, C.2    Gusterson, B.A.3    Cooper, C.S.4
  • 29
    • 53049083206 scopus 로고    scopus 로고
    • Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations
    • Ren YX, Finckenstein FG, Abdueva DA, et al: Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res 68: 6587-6597, 2008.
    • (2008) Cancer Res , vol.68 , pp. 6587-6597
    • Ren, Y.X.1    Finckenstein, F.G.2    Abdueva, D.A.3
  • 30
    • 0036786348 scopus 로고    scopus 로고
    • CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion
    • Libura J, Drukala J, Majka M, et al: CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. Blood 100: 2597-2606, 2002.
    • (2002) Blood , vol.100 , pp. 2597-2606
    • Libura, J.1    Drukala, J.2    Majka, M.3
  • 32
    • 78049487451 scopus 로고    scopus 로고
    • Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas
    • Grymula K, Tarnowski M, Wysoczynski M, et al: Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas. Int J Cancer 127: 2554-2568, 2010.
    • (2010) Int J Cancer , vol.127 , pp. 2554-2568
    • Grymula, K.1    Tarnowski, M.2    Wysoczynski, M.3
  • 33
    • 75149142302 scopus 로고    scopus 로고
    • Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas
    • Tarnowski M, Grymula K, Reca R, et al: Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas. Mol Cancer Res 8: 1-14, 2010.
    • (2010) Mol Cancer Res , vol.8 , pp. 1-14
    • Tarnowski, M.1    Grymula, K.2    Reca, R.3
  • 36
    • 0033205985 scopus 로고    scopus 로고
    • Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma
    • Anderson J, Gordon A, McManus A, Shipley J and Pritchard-Jones K: Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia 1: 340-348, 1999.
    • (1999) Neoplasia , vol.1 , pp. 340-348
    • Anderson, J.1    Gordon, A.2    McManus, A.3    Shipley, J.4    Pritchard-Jones, K.5
  • 38
    • 0028229910 scopus 로고
    • Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma
    • Zhan S, Shapiro DN and Helman LJ: Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J Clin Invest 94: 445-448, 1994. (Pubitemid 24218124)
    • (1994) Journal of Clinical Investigation , vol.94 , Issue.1 , pp. 445-448
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3
  • 39
    • 77957563020 scopus 로고    scopus 로고
    • Prospective identification and skeletal localization of cells capable of multilineage differentiation in vivo
    • Taichman RS, Wang Z, Shiozawa Y, et al: Prospective identification and skeletal localization of cells capable of multilineage differentiation in vivo. Stem Cells Dev 19: 1557-1570, 2010.
    • (2010) Stem Cells Dev , vol.19 , pp. 1557-1570
    • Taichman, R.S.1    Wang, Z.2    Shiozawa, Y.3
  • 40
    • 0037193659 scopus 로고    scopus 로고
    • Structural characterization of Rasgrf1 and a novel linked imprinted locus
    • DOI 10.1016/S0378-1119(02)00601-7, PII S0378111902006017
    • De la Puente A, Hall J, Wu YZ, et al: Structural characterization of Rasgrf1 and a novel linked imprinted locus. Gene 291: 287-297, 2002. (Pubitemid 34722397)
    • (2002) Gene , vol.291 , Issue.1-2 , pp. 287-297
    • De La, P.A.1    Hall, J.2    Wu, Y.-Z.3    Leone, G.4    Peters, J.5    Yoon, B.-J.6    Soloway, P.7    Plass, C.8
  • 43
    • 0026523616 scopus 로고
    • Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator
    • Martegani E, Vanoni M, Zippel R, et al: Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator. EMBO J 11: 2151-2157, 1992.
    • (1992) EMBO J , vol.11 , pp. 2151-2157
    • Martegani, E.1    Vanoni, M.2    Zippel, R.3
  • 44
    • 0029742101 scopus 로고    scopus 로고
    • The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium
    • Buchsbaum R, Telliez JB, Goonesekera S and Feig LA: The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium. Mol Cell Biol 16: 4888-4896, 1996. (Pubitemid 26272144)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.9 , pp. 4888-4896
    • Buchsbaum, R.1    Telliez, J.-B.2    Goonesekera, S.3    Feig, L.A.4
  • 46
    • 16244392404 scopus 로고    scopus 로고
    • p75-Ras-GRF1 is a c-Jun/AP-1 target protein: Its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells
    • DOI 10.1128/MCB.25.8.3324-3337.2005
    • Leaner VD, Donninger H, Ellis CA, Clark GJ and Birrer MJ: p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells. Mol Cell Biol 25: 3324-3337, 2005. (Pubitemid 40464332)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.8 , pp. 3324-3337
    • Leaner, V.D.1    Donninger, H.2    Ellis, C.A.3    Clark, G.J.4    Birrer, M.J.5
  • 49
    • 33646241782 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2-mediated interaction
    • Forlani G, Baldassa S, Lavagni P, Sturani E and Zippel R: The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2-mediated interaction. FEBS J 273: 2127-2138, 2006.
    • (2006) FEBS J , vol.273 , pp. 2127-2138
    • Forlani, G.1    Baldassa, S.2    Lavagni, P.3    Sturani, E.4    Zippel, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.