-
1
-
-
0035890906
-
Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells
-
Abu-Ghazaleh, R., J. Kabir, H. Jia, M. Lobo, and I. Zachary. 2001. Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells. Biochem. J. 360:255-264.
-
(2001)
Biochem. J.
, vol.360
, pp. 255-264
-
-
Abu-Ghazaleh, R.1
Kabir, J.2
Jia, H.3
Lobo, M.4
Zachary, I.5
-
2
-
-
0034120314
-
Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line
-
Biroccio, A., A. Candiloro, M. Mottolese, O. Sapora, A. Albini, G. Zupi, and D. Del Bufalo. 2000. Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line. FASEB J. 14:652-660.
-
(2000)
FASEB J.
, vol.14
, pp. 652-660
-
-
Biroccio, A.1
Candiloro, A.2
Mottolese, M.3
Sapora, O.4
Albini, A.5
Zupi, G.6
Del Bufalo, D.7
-
3
-
-
0033602091
-
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization
-
Dougher, M., and B. I. Terman. 1999. Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization. Oncogene 18:1619-1627.
-
(1999)
Oncogene
, vol.18
, pp. 1619-1627
-
-
Dougher, M.1
Terman, B.I.2
-
4
-
-
0030020131
-
Tumor angiogenesis and tissue factor
-
Folkman, J. 1996. Tumor angiogenesis and tissue factor. Nat. Med. 2:167-168.
-
(1996)
Nat. Med.
, vol.2
, pp. 167-168
-
-
Folkman, J.1
-
5
-
-
0024549349
-
Induction of angiogenesis during the transition from hyperplasia to neoplasia
-
Folkman, J., K. Watson, D. Ingber, and D. Hanahan. 1989. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 339:58-61.
-
(1989)
Nature
, vol.339
, pp. 58-61
-
-
Folkman, J.1
Watson, K.2
Ingber, D.3
Hanahan, D.4
-
7
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
8
-
-
0032973197
-
Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta
-
Horiuchi, K., N. Amizuka, S. Takeshita, H. Takamatsu, M. Katsuura, H. Ozawa, Y. Toyama, L. F. Bonewald, and A. Kudo. 1999. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J. Bone Miner. Res. 14:1239-1249.
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1239-1249
-
-
Horiuchi, K.1
Amizuka, N.2
Takeshita, S.3
Takamatsu, H.4
Katsuura, M.5
Ozawa, H.6
Toyama, Y.7
Bonewald, L.F.8
Kudo, A.9
-
9
-
-
0034547973
-
Differential gene expression between normal and tumor-derived ovarian epithelial cells
-
Ismail, R. S., R. L. Baldwin, J. Fang, D. Browning, B. Y. Karlan, J. C. Gasson, and D. D. Chang. 2000. Differential gene expression between normal and tumor-derived ovarian epithelial cells. Cancer Res. 60:6744-6749.
-
(2000)
Cancer Res.
, vol.60
, pp. 6744-6749
-
-
Ismail, R.S.1
Baldwin, R.L.2
Fang, J.3
Browning, D.4
Karlan, B.Y.5
Gasson, J.C.6
Chang, D.D.7
-
10
-
-
0030012507
-
Regulation of angiogenesis by SPARC and angiostatin: Implications for tumor cell biology
-
Jendraschak, E., and E. H. Sage. 1996. Regulation of angiogenesis by SPARC and angiostatin: implications for tumor cell biology. Semin. Cancer Biol. 7:139-146.
-
(1996)
Semin. Cancer Biol.
, vol.7
, pp. 139-146
-
-
Jendraschak, E.1
Sage, E.H.2
-
11
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
Jiang, X. R., G. Jimenez, E. Chang, M. Frolkis, B. Kusler, M. Sage, M. Beeche, A. G. Bodnar, G. M. Wahl, T. D. Tisty, and C. P. Chiu. 1999. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat. Genet. 21:111-114.
-
(1999)
Nat. Genet.
, vol.21
, pp. 111-114
-
-
Jiang, X.R.1
Jimenez, G.2
Chang, E.3
Frolkis, M.4
Kusler, B.5
Sage, M.6
Beeche, M.7
Bodnar, A.G.8
Wahl, G.M.9
Tisty, T.D.10
Chiu, C.P.11
-
12
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Kasahara, Y., R. M. Tuder, L. Taraseviciene-Stewart, T. D. Le Cras, S. Abman, P. K. Hirth, J. Waltenberger, and N. F. Voelkel. 2000. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J. Clin. Investig. 106:1311-1319.
-
(2000)
J. Clin. Investig.
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
Le Cras, T.D.4
Abman, S.5
Hirth, P.K.6
Waltenberger, J.7
Voelkel, N.F.8
-
13
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim, K. J., B. Li, J. Winer, M. Armanini, N. Gillett, H. S. Phillips, and N. Ferrara. 1993. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
14
-
-
0033231026
-
A public database for gene expression in human cancers
-
Lal, A., A. E. Lash, S. F. Altschul, V. Velculescu, L. Zhang, R. E. McLendon, M. A. Marra, C. Prange, P. J. Morin, K. Polyak, N. Papadopoulos, B. Vogelstein, K. W. Kinzler, R. L. Strausberg, and G. J. Riggins. 1999. A public database for gene expression in human cancers. Cancer Res. 59:5403-5407.
-
(1999)
Cancer Res.
, vol.59
, pp. 5403-5407
-
-
Lal, A.1
Lash, A.E.2
Altschul, S.F.3
Velculescu, V.4
Zhang, L.5
McLendon, R.E.6
Marra, M.A.7
Prange, C.8
Morin, P.J.9
Polyak, K.10
Papadopoulos, N.11
Vogelstein, B.12
Kinzler, K.W.13
Strausberg, R.L.14
Riggins, G.J.15
-
15
-
-
0031056656
-
Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells
-
Ledda, M. F., S. Adris, A. I. Bravo, C. Kairiyama, L. Bover, Y. Chernajovsky, J. Mordoh, and O. L. Podhajcer. 1997. Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells. Nat. Med. 3:171-176.
-
(1997)
Nat. Med.
, vol.3
, pp. 171-176
-
-
Ledda, M.F.1
Adris, S.2
Bravo, A.I.3
Kairiyama, C.4
Bover, L.5
Chernajovsky, Y.6
Mordoh, J.7
Podhajcer, O.L.8
-
16
-
-
0031965353
-
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
-
Lin, P., S. Sankar, S. Shan, M. W. Dewhirst, P. J. Polverini, T. Q. Quinn, and K. G. Peters. 1998. Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ. 9:49-58.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 49-58
-
-
Lin, P.1
Sankar, S.2
Shan, S.3
Dewhirst, M.W.4
Polverini, P.J.5
Quinn, T.Q.6
Peters, K.G.7
-
17
-
-
0032745920
-
Transcriptional regulation of stromelysin-1 gene expression is altered during progression of mouse mammary epithelial cells from functionally normal to malignant
-
Lochter, A., Z. Werb, and M. J. Bissell. 1999. Transcriptional regulation of stromelysin-1 gene expression is altered during progression of mouse mammary epithelial cells from functionally normal to malignant. Matrix Biol. 18:455-467.
-
(1999)
Matrix Biol.
, vol.18
, pp. 455-467
-
-
Lochter, A.1
Werb, Z.2
Bissell, M.J.3
-
18
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden, D., K. Hattori, S. Dias, C. Costa, P. Blaikie, L. Butros, A. Chadburn, B. Heissig, W. Marks, L. Witte, Y. Wu, D. Hicklin, Z. Zhu, N. R. Hackett, R. G. Crystal, M. A. Moore, K. A. Hajjar, K. Manova, R. Benezra, and S. Rafii. 2001. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7:1194-1201.
-
(2001)
Nat. Med.
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
Costa, C.4
Blaikie, P.5
Butros, L.6
Chadburn, A.7
Heissig, B.8
Marks, W.9
Witte, L.10
Wu, Y.11
Hicklin, D.12
Zhu, Z.13
Hackett, N.R.14
Crystal, R.G.15
Moore, M.A.16
Hajjar, K.A.17
Manova, K.18
Benezra, R.19
Rafii, S.20
more..
-
19
-
-
0029863730
-
Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo
-
Millauer, B., M. P. Longhi, K. H. Plate, L. K. Shawver, W. Risau, A. Ullrich, and L. M. Strawn. 1996. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo. Cancer Res. 56:1615-1620.
-
(1996)
Cancer Res.
, vol.56
, pp. 1615-1620
-
-
Millauer, B.1
Longhi, M.P.2
Plate, K.H.3
Shawver, L.K.4
Risau, W.5
Ullrich, A.6
Strawn, L.M.7
-
20
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
Morales, C. P., S. E. Holt, M. Ouellette, K. J. Kaur, Y. Yan, K. S. Wilson, M. A. White, W. E. Wright, and J. W. Shay. 1999. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat. Genet. 21:115-118.
-
(1999)
Nat. Genet.
, vol.21
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
21
-
-
13044304179
-
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
-
Perou, C. M., S. S. Jeffrey, M. van de Rijn, C. A. Rees, M. B. Eisen, D. T. Ross, A. Pergamenschikov, C. F. Williams, S. X. Zhu, J. C. Lee, D. Lashkari, D. Shalon, P. O. Brown, and D. Botstein. 1999. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl. Acad. Sci. USA 96:9212-9217.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9212-9217
-
-
Perou, C.M.1
Jeffrey, S.S.2
Van De Rijn, M.3
Rees, C.A.4
Eisen, M.B.5
Ross, D.T.6
Pergamenschikov, A.7
Williams, C.F.8
Zhu, S.X.9
Lee, J.C.10
Lashkari, D.11
Shalon, D.12
Brown, P.O.13
Botstein, D.14
-
22
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C. M., T. Sorlie, M. B. Eisen, M. van de Rijn, S. S. Jeffrey, C. A. Rees, J. R. Pollack, D. T. Ross, H. Johnsen, L. A. Akslen, O. Fluge, A. Pergamenschikov, C. Williams, S. X. Zhu, P. E. Lonning, A. L. Borresen-Dale, P. O. Brown, and D. Botstein. 2000. Molecular portraits of human breast tumours. Nature 406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
Pollack, J.R.7
Ross, D.T.8
Johnsen, H.9
Akslen, L.A.10
Fluge, O.11
Pergamenschikov, A.12
Williams, C.13
Zhu, S.X.14
Lonning, P.E.15
Borresen-Dale, A.L.16
Brown, P.O.17
Botstein, D.18
-
23
-
-
0032953810
-
Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: Establishment of working models for human micrometastases
-
Putz, E., K. Witter, S. Offner, P. Stosiek, A. Zippelius, J. Johnson, R. Zahn, G. Riethmuller, and K. Pantel. 1999. Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for human micrometastases. Cancer Res. 59:241-248.
-
(1999)
Cancer Res.
, vol.59
, pp. 241-248
-
-
Putz, E.1
Witter, K.2
Offner, S.3
Stosiek, P.4
Zippelius, A.5
Johnson, J.6
Zahn, R.7
Riethmuller, G.8
Pantel, K.9
-
24
-
-
0038521296
-
Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model
-
Rich, J. N., Q. Shi, M. Hjelmeland, T. J. Cummings, C. T. Kuan, D. D. Bigner, C. M. Counter, and X. F. Wang. 2003. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J. Biol. Chem. 278:15951-15957.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15951-15957
-
-
Rich, J.N.1
Shi, Q.2
Hjelmeland, M.3
Cummings, T.J.4
Kuan, C.T.5
Bigner, D.D.6
Counter, C.M.7
Wang, X.F.8
-
25
-
-
0035935253
-
Serum level of the periostin, a homologue of an insect cell adhesion molecule, in thymoma patients
-
Sasaki, H., D. Auclair, M. Kajl, I. Fukai, M. Kiriyama, Y. Yamakawa, Y. Fujii, and L. B. Chen. 2001. Serum level of the periostin, a homologue of an insect cell adhesion molecule, in thymoma patients. Cancer Lett. 172:37-42.
-
(2001)
Cancer Lett.
, vol.172
, pp. 37-42
-
-
Sasaki, H.1
Auclair, D.2
Kajl, M.3
Fukai, I.4
Kiriyama, M.5
Yamakawa, Y.6
Fujii, Y.7
Chen, L.B.8
-
26
-
-
0035880704
-
Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas
-
Sasaki, H., M. Dai, D. Auclair, I. Fukai, M. Kiriyama, Y. Yamakawa, Y. Fujii, and L. B. Chen. 2001. Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas. Cancer 92:843-848.
-
(2001)
Cancer
, vol.92
, pp. 843-848
-
-
Sasaki, H.1
Dai, M.2
Auclair, D.3
Fukai, I.4
Kiriyama, M.5
Yamakawa, Y.6
Fujii, Y.7
Chen, L.B.8
-
27
-
-
0037318744
-
Elevated serum periostin levels in patients with bone metastases from breast but not lung cancer
-
Sasaki, H., C. Y. Yu, M. Dai, C. Tam, M. Loda, D. Auclair, L. B. Chen, and A. Elias. 2003. Elevated serum periostin levels in patients with bone metastases from breast but not lung cancer. Breast Cancer Res. Treat. 77:245-252.
-
(2003)
Breast Cancer Res. Treat.
, vol.77
, pp. 245-252
-
-
Sasaki, H.1
Yu, C.Y.2
Dai, M.3
Tam, C.4
Loda, M.5
Auclair, D.6
Chen, L.B.7
Elias, A.8
-
28
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
-
Stacker, S. A., C. Caesar, M. E. Baldwin, G. E. Thornton, R. A. Williams, R. Prevo, D. G. Jackson, S. Nishikawa, H. Kubo, and M. G. Achen. 2001. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat. Med. 7:186-191.
-
(2001)
Nat. Med.
, vol.7
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
Thornton, G.E.4
Williams, R.A.5
Prevo, R.6
Jackson, D.G.7
Nishikawa, S.8
Kubo, H.9
Achen, M.G.10
-
29
-
-
0027185670
-
Osteoblast-specific factor 2: Cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I
-
Takeshita, S., R. Kikuno, K. Tezuka, and E. Amann. 1993. Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I. Biochem. J. 294:271-278.
-
(1993)
Biochem. J.
, vol.294
, pp. 271-278
-
-
Takeshita, S.1
Kikuno, R.2
Tezuka, K.3
Amann, E.4
-
30
-
-
0033615968
-
Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein
-
Tang, S., Y. Gao, and J. A. Ware. 1999. Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein. J. Cell Biol. 147:1073-1084.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1073-1084
-
-
Tang, S.1
Gao, Y.2
Ware, J.A.3
-
31
-
-
0034661728
-
Targeting angiogenesis inhibits tumor infiltration and expression of the pro-invasive protein SPARC
-
Vajkoczy, P., M. D. Menger, R. Goldbrunner, S. Ge, T. A. Fong, B. Vollmar, L. Schilling, A. Ullrich, K. P. Hirth, J. C. Tonn, P. Schmiedek, and S. A. Rempel. 2000. Targeting angiogenesis inhibits tumor infiltration and expression of the pro-invasive protein SPARC. Int. J. Cancer 87:261-268.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 261-268
-
-
Vajkoczy, P.1
Menger, M.D.2
Goldbrunner, R.3
Ge, S.4
Fong, T.A.5
Vollmar, B.6
Schilling, L.7
Ullrich, A.8
Hirth, K.P.9
Tonn, J.C.10
Schmiedek, P.11
Rempel, S.A.12
-
32
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van 't Veer, L. J., H. Dai, M. J. van de Vijver, Y. D. He, A. A. Hart, M. Mao, H. L. Peterse, K. van der Kooy, M. J. Marton, A. T. Witteveen, G. J. Schreiber, R. M. Kerkhoven, C. Roberts, P. S. Linsley, R. Bernards, and S. H. Friend. 2002. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415:530-536.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
Van 't Veer, L.J.1
Dai, H.2
Van De Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
Peterse, H.L.7
Van Der Kooy, K.8
Marton, M.J.9
Witteveen, A.T.10
Schreiber, G.J.11
Kerkhoven, R.M.12
Roberts, C.13
Linsley, P.S.14
Bernards, R.15
Friend, S.H.16
-
34
-
-
0028789793
-
Serial analysis of gene expression
-
Velculescu, V. E., L. Zhang, B. Vogelstein, and K. W. Kinzler. 1995. Serial analysis of gene expression. Science 270:484-487.
-
(1995)
Science
, vol.270
, pp. 484-487
-
-
Velculescu, V.E.1
Zhang, L.2
Vogelstein, B.3
Kinzler, K.W.4
-
35
-
-
0035949684
-
Predicting the clinical status of human breast cancer by using gene expression profiles
-
West, M., C. Blanchette, H. Dressman, E. Huang, S. Ishida, R. Spang, H. Zuzan, J. A. Olson, Jr., J. R. Marks, and J. R. Nevins. 2001. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc. Natl. Acad. Sci. USA 98:11462-11467.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11462-11467
-
-
West, M.1
Blanchette, C.2
Dressman, H.3
Huang, E.4
Ishida, S.5
Spang, R.6
Zuzan, H.7
Olson Jr., J.A.8
Marks, J.R.9
Nevins, J.R.10
-
36
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos, G. D., S. Davis, N. W. Gale, J. S. Rudge, S. J. Wiegand, and J. Holash. 2000. Vascular-specific growth factors and blood vessel formation. Nature 407:242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
37
-
-
0030962307
-
Gene expression profiles in normal and cancer cells
-
Zhang, L., W. Zhou, V. E. Velculescu, S. E. Kern, R. H. Hruban, S. R. Hamilton, B. Vogelstein, and K. W. Kinzler. 1997. Gene expression profiles in normal and cancer cells. Science 276:1268-1272.
-
(1997)
Science
, vol.276
, pp. 1268-1272
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Zhang, L.1
Zhou, W.2
Velculescu, V.E.3
Kern, S.E.4
Hruban, R.H.5
Hamilton, S.R.6
Vogelstein, B.7
Kinzler, K.W.8
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