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Volumn 4, Issue 6, 2012, Pages 379-392

Beyond average: Potential for measurement of short telomeres

Author keywords

Quantitative FISH; Quantitative PCR; Short telomeres; Telomere length; Telomeric southern blot

Indexed keywords


EID: 84864981283     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100462     Document Type: Review
Times cited : (84)

References (52)
  • 1
    • 0037148277 scopus 로고    scopus 로고
    • Protection of mammalian telomeres
    • de Lange T. Protection of mammalian telomeres. Oncogene. 2002; 21:532-540.
    • (2002) Oncogene , vol.21 , pp. 532-540
    • de Lange, T.1
  • 2
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB and Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature. 1990; 345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 3
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn EH. Switching and signaling at the telomere. Cell. 2001; 106:661-673.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 4
    • 0037148271 scopus 로고    scopus 로고
    • Telomerase in the human organism
    • Collins K and Mitchell JR. Telomerase in the human organism. Oncogene. 2002; 21:564-579.
    • (2002) Oncogene , vol.21 , pp. 564-579
    • Collins, K.1    Mitchell, J.R.2
  • 5
    • 34248370975 scopus 로고    scopus 로고
    • High-throughput telomere length quantification by FISH and its application to human population studies
    • Canela A, Vera E, Klatt P and Blasco MA. High-throughput telomere length quantification by FISH and its application to human population studies. Proc Natl Acad Sci U S A. 2007; 104:5300-5305.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5300-5305
    • Canela, A.1    Vera, E.2    Klatt, P.3    Blasco, M.A.4
  • 6
    • 40349085766 scopus 로고    scopus 로고
    • The longest telomeres: a general signature of adult stem cell compartments
    • Flores I, Canela A, Vera E, Tejera A, Cotsarelis G and Blasco MA. The longest telomeres: a general signature of adult stem cell compartments. Genes Dev. 2008; 22:654-667.
    • (2008) Genes Dev , vol.22 , pp. 654-667
    • Flores, I.1    Canela, A.2    Vera, E.3    Tejera, A.4    Cotsarelis, G.5    Blasco, M.A.6
  • 7
    • 0032080191 scopus 로고    scopus 로고
    • Telomerase activity in candidate stem cells from fetal liver and adult bone marrow
    • Yui J, Chiu CP and Lansdorp PM. Telomerase activity in candidate stem cells from fetal liver and adult bone marrow. Blood. 1998; 91:3255-3262.
    • (1998) Blood , vol.91 , pp. 3255-3262
    • Yui, J.1    Chiu, C.P.2    Lansdorp, P.M.3
  • 8
    • 44349136891 scopus 로고    scopus 로고
    • Telomere dysfunction and tumour suppression: the senescence connection
    • Deng Y, Chan SS and Chang S. Telomere dysfunction and tumour suppression: the senescence connection. Nat Rev Cancer. 2008; 8:450-458.
    • (2008) Nat Rev Cancer , vol.8 , pp. 450-458
    • Deng, Y.1    Chan, S.S.2    Chang, S.3
  • 9
    • 34447543913 scopus 로고    scopus 로고
    • Cellular senescence in cancer and aging
    • Collado M, Blasco MA and Serrano M. Cellular senescence in cancer and aging. Cell. 2007; 130:223-233.
    • (2007) Cell , vol.130 , pp. 223-233
    • Collado, M.1    Blasco, M.A.2    Serrano, M.3
  • 10
    • 34548667973 scopus 로고    scopus 로고
    • Telomere length, stem cells and aging
    • Blasco MA. Telomere length, stem cells and aging. Nat Chem Biol. 2007; 3:640-649.
    • (2007) Nat Chem Biol , vol.3 , pp. 640-649
    • Blasco, M.A.1
  • 11
    • 0034769105 scopus 로고    scopus 로고
    • Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
    • Samper E, Flores JM and Blasco MA. Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep. 2001; 2:800-807.
    • (2001) EMBO Rep , vol.2 , pp. 800-807
    • Samper, E.1    Flores, J.M.2    Blasco, M.A.3
  • 12
    • 0035812845 scopus 로고    scopus 로고
    • The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
    • Hemann MT, Strong MA, Hao LY and Greider CW. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell. 2001; 107:67-77.
    • (2001) Cell , vol.107 , pp. 67-77
    • Hemann, M.T.1    Strong, M.A.2    Hao, L.Y.3    Greider, C.W.4
  • 16
    • 0037308404 scopus 로고    scopus 로고
    • Association between telomere length in blood and mortality in people aged 60 years or older
    • Cawthon RM, Smith KR, O'Brien E, Sivatchenko A and Kerber RA. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet. 2003; 361:393-395.
    • (2003) Lancet , vol.361 , pp. 393-395
    • Cawthon, R.M.1    Smith, K.R.2    O'Brien, E.3    Sivatchenko, A.4    Kerber, R.A.5
  • 23
    • 0024362809 scopus 로고
    • Human telomeres contain at least three types of G-rich repeat distributed nonrandomly
    • Allshire RC, Dempster M and Hastie ND. Human telomeres contain at least three types of G-rich repeat distributed nonrandomly. Nucleic Acids Res. 1989; 17:4611-4627.
    • (1989) Nucleic Acids Res , vol.17 , pp. 4611-4627
    • Allshire, R.C.1    Dempster, M.2    Hastie, N.D.3
  • 24
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling D and Cooke HJ. Hypervariable ultra-long telomeres in mice. Nature. 1990; 347:400-402.
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 26
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
    • Rufer N, Dragowska W, Thornbury G, Roosnek E and Lansdorp PM. Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol. 1998; 16:743-747.
    • (1998) Nat Biotechnol , vol.16 , pp. 743-747
    • Rufer, N.1    Dragowska, W.2    Thornbury, G.3    Roosnek, E.4    Lansdorp, P.M.5
  • 28
    • 2342419515 scopus 로고    scopus 로고
    • Telomere measurement by quantitative PCR
    • Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002; 30:e47.
    • (2002) Nucleic Acids Res , vol.30
    • Cawthon, R.M.1
  • 29
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB and Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 1992; 11:1921-1929.
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 31
    • 0026341239 scopus 로고
    • Sequenceselective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen PE, Egholm M, Berg RH and Buchardt O. Sequenceselective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science. 1991; 254:1497-1500.
    • (1991) Science , vol.254 , pp. 1497-1500
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 34
    • 0033178240 scopus 로고    scopus 로고
    • Telomere length measurements using digital fluorescence microscopy
    • Poon SS, Martens UM, Ward RK and Lansdorp PM. Telomere length measurements using digital fluorescence microscopy. Cytometry. 1999; 36:267-278.
    • (1999) Cytometry , vol.36 , pp. 267-278
    • Poon, S.S.1    Martens, U.M.2    Ward, R.K.3    Lansdorp, P.M.4
  • 35
    • 0028557213 scopus 로고
    • Stringent sequence requirements for the formation of human telomeres
    • Hanish JP, Yanowitz JL and de Lange T. Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci U S A. 1994; 91:8861-8865.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.L.2    de Lange, T.3
  • 37
    • 0343228751 scopus 로고    scopus 로고
    • Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
    • Gonzalez-Suarez E, Samper E, Flores JM and Blasco MA. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet. 2000; 26:114-117.
    • (2000) Nat Genet , vol.26 , pp. 114-117
    • Gonzalez-Suarez, E.1    Samper, E.2    Flores, J.M.3    Blasco, M.A.4
  • 40
    • 79960322707 scopus 로고    scopus 로고
    • The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
    • de Jesus BB, Schneeberger K, Vera E, Tejera A, Harley CB and Blasco MA. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell. 2011; 10:604-621.
    • (2011) Aging Cell , vol.10 , pp. 604-621
    • de Jesus, B.B.1    Schneeberger, K.2    Vera, E.3    Tejera, A.4    Harley, C.B.5    Blasco, M.A.6
  • 41
    • 63349111567 scopus 로고    scopus 로고
    • Telomere length measurement by a novel monochrome multiplex quantitative PCR method
    • Cawthon RM. Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res. 2009; 37:e21.
    • (2009) Nucleic Acids Res , vol.37
    • Cawthon, R.M.1
  • 42
    • 79960825030 scopus 로고    scopus 로고
    • A quantitative PCR method for measuring absolute telomere length
    • O'Callaghan NJ and Fenech M. A quantitative PCR method for measuring absolute telomere length. Biol Proced Online. 13:3.
    • Biol Proced Online , vol.13 , pp. 3
    • O'Callaghan, N.J.1    Fenech, M.2
  • 43
    • 0032864304 scopus 로고    scopus 로고
    • Simple, rapid, quantitative, and sensitive detection of telomere repeats in cell lysate by a hybridization protection assay
    • Nakamura Y, Hirose M, Matsuo H, Tsuyama N, Kamisango K and Ide T. Simple, rapid, quantitative, and sensitive detection of telomere repeats in cell lysate by a hybridization protection assay. Clin Chem. 1999; 45:1718-1724.
    • (1999) Clin Chem , vol.45 , pp. 1718-1724
    • Nakamura, Y.1    Hirose, M.2    Matsuo, H.3    Tsuyama, N.4    Kamisango, K.5    Ide, T.6
  • 44
    • 0037908790 scopus 로고    scopus 로고
    • Mouse telomere analysis using an optimized primed in situ (PRINS) labeling technique
    • Lavoie J, Bronsard M, Lebel M and Drouin R. Mouse telomere analysis using an optimized primed in situ (PRINS) labeling technique. Chromosoma. 2003; 111:438-444.
    • (2003) Chromosoma , vol.111 , pp. 438-444
    • Lavoie, J.1    Bronsard, M.2    Lebel, M.3    Drouin, R.4
  • 45
    • 0037313185 scopus 로고    scopus 로고
    • Extensive allelic variation and ultrashort telomeres in senescent human cells
    • Baird DM, Rowson J, Wynford-Thomas D and Kipling D. Extensive allelic variation and ultrashort telomeres in senescent human cells. Nat Genet. 2003; 33:203-207.
    • (2003) Nat Genet , vol.33 , pp. 203-207
    • Baird, D.M.1    Rowson, J.2    Wynford-Thomas, D.3    Kipling, D.4
  • 46
    • 33144456602 scopus 로고    scopus 로고
    • Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans
    • Britt-Compton B, Rowson J, Locke M, Mackenzie I, Kipling D and Baird DM. Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans. Hum Mol Genet. 2006; 15:725-733.
    • (2006) Hum Mol Genet , vol.15 , pp. 725-733
    • Britt-Compton, B.1    Rowson, J.2    Locke, M.3    Mackenzie, I.4    Kipling, D.5    Baird, D.M.6
  • 47
    • 77956663122 scopus 로고    scopus 로고
    • The load of short telomeres, estimated by a new method, Universal STELA, correlates with number of senescent cells
    • Bendix L, Horn PB, Jensen UB, Rubelj I and Kolvraa S. The load of short telomeres, estimated by a new method, Universal STELA, correlates with number of senescent cells. Aging Cell. 9:383-397.
    • Aging Cell , vol.9 , pp. 383-397
    • Bendix, L.1    Horn, P.B.2    Jensen, U.B.3    Rubelj, I.4    Kolvraa, S.5
  • 48
    • 2442617343 scopus 로고    scopus 로고
    • Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC
    • Vulliamy T, Marrone A, Szydlo R, Walne A, Mason PJ and Dokal I. Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC. Nat Genet. 2004; 36:447-449.
    • (2004) Nat Genet , vol.36 , pp. 447-449
    • Vulliamy, T.1    Marrone, A.2    Szydlo, R.3    Walne, A.4    Mason, P.J.5    Dokal, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.