메뉴 건너뛰기




Volumn 41, Issue 3, 2012, Pages 1061-1067

Autoantibodies against glucose-regulated protein 78 as serological diagnostic biomarkers in hepatocellular carcinoma

Author keywords

Autoantibody; Biomarker; GRP78; Hepatocellular carcinoma; Immunodiagnosis

Indexed keywords

ALPHA FETOPROTEIN ANTIBODY; AUTOANTIBODY; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 78 AUTOANTIBODY; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84864967298     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1515     Document Type: Article
Times cited : (39)

References (47)
  • 2
    • 26444553601 scopus 로고    scopus 로고
    • Early detection and curative treatment of early-stage hepatocellular carcinoma
    • Kudo M: Early detection and curative treatment of early-stage hepatocellular carcinoma. Clin Gastroenterol Hepatol 3: S144-S148, 2005.
    • (2005) Clin Gastroenterol Hepatol , vol.3
    • Kudo, M.1
  • 3
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • Llovet JM, Burroughs A and Bruix J: Hepatocellular carcinoma. Lancet 362: 1907-1917, 2003. (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 4
    • 77953708568 scopus 로고    scopus 로고
    • Surveillance and early diagnosis of hepatocellular carcinoma
    • Lencioni R: Surveillance and early diagnosis of hepatocellular carcinoma. Dig Liver Dis 42: S223-S227, 2010.
    • (2010) Dig Liver Dis , vol.42
    • Lencioni, R.1
  • 5
    • 3843125293 scopus 로고    scopus 로고
    • Randomized controlled trial of screening for hepatocellular carcinoma
    • Zhang BH, Yang BH and Tang ZY: Randomized controlled trial of screening for hepatocellular carcinoma. J Cancer Res Clin Oncol 130: 417-422, 2004.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 417-422
    • Zhang, B.H.1    Yang, B.H.2    Tang, Z.Y.3
  • 6
    • 0034027972 scopus 로고    scopus 로고
    • Improved survival with screening for hepatocellular carcinoma
    • DOI 10.1053/lv.2000.4875
    • Wong LL, Limm WM, Severino R and Wong LM: Improved survival with screening for hepatocellular carcinoma. Liver Transpl 6: 320-325, 2000. (Pubitemid 30317228)
    • (2000) Liver Transplantation , vol.6 , Issue.3 , pp. 320-325
    • Wong, L.L.1    Limm, W.M.2    Severino, R.3    Wong, L.M.4
  • 7
    • 7044264739 scopus 로고    scopus 로고
    • α-fetoprotein and ultrasonography screening for hepatocellular carcinoma
    • DOI 10.1053/j.gastro.2004.09.023, PII S0016508504016026
    • Daniele B, Bencivenga A, Megna AS and Tinessa V: α-fetoprotein and ultrasonography screening for hepatocellular carcinoma. Gastroenterology 127: S108-S112, 2004. (Pubitemid 39423377)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • Daniele, B.1    Bencivenga, A.2    Megna, A.S.3    Tinessa, V.4
  • 8
    • 0035189977 scopus 로고    scopus 로고
    • Autoantibodies as reporters identifying aberrant cellular mechanisms in tumorigenesis
    • Tan EM: Autoantibodies as reporters identifying aberrant cellular mechanisms in tumorigenesis. J Clin Invest 108: 1411-1415, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 1411-1415
    • Tan, E.M.1
  • 9
    • 41149178259 scopus 로고    scopus 로고
    • Autoantibodies to tumor-associated antigens: Reporters from the immune system
    • DOI 10.1111/j.1600-065X.2008.00611.x
    • Tan EM and Zhang JY: Autoantibodies to tumor-associated antigens: reporters from the immune system. Immunol Rev 222: 328-340, 2008. (Pubitemid 351430373)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 328-340
    • Tan, E.M.1    Zhang, J.2
  • 10
    • 77950615581 scopus 로고    scopus 로고
    • Autoantibodies to tumor-associated antigens as diagnostic biomarkers in hepatocellular carcinoma and other solid tumors
    • Zhang JY and Tan EM: Autoantibodies to tumor-associated antigens as diagnostic biomarkers in hepatocellular carcinoma and other solid tumors. Expert Rev Mol Diagn 10: 321-328, 2010.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 321-328
    • Zhang, J.Y.1    Tan, E.M.2
  • 11
    • 33846604550 scopus 로고    scopus 로고
    • Mini-array of multiple tumor-associated antigens to enhance autoantibody detection for immunodiagnosis of hepatocellular carcinoma
    • Zhang JY: Mini-array of multiple tumor-associated antigens to enhance autoantibody detection for immunodiagnosis of hepatocellular carcinoma. Autoimmun Rev 6: 143-148, 2007.
    • (2007) Autoimmun Rev , vol.6 , pp. 143-148
    • Zhang, J.Y.1
  • 12
    • 75949088039 scopus 로고    scopus 로고
    • Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma
    • Chen Y, Zhou YS, Qiu SM, Wang KJ, Liu SW, Peng XX, Li JF, et al: Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma. Cancer Lett 289: 32-39, 2010.
    • (2010) Cancer Lett , vol.289 , pp. 32-39
    • Chen, Y.1    Zhou, Y.S.2    Qiu, S.M.3    Wang, K.J.4    Liu, S.W.5    Peng, X.X.6    Li, J.F.7
  • 13
    • 0035423875 scopus 로고    scopus 로고
    • The glucose-regulated proteins: Stress induction and clinical applications
    • Lee AS: The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci 26: 504-510, 2001.
    • (2001) Trends Biochem Sci , vol.26 , pp. 504-510
    • Lee, A.S.1
  • 14
    • 34248571826 scopus 로고    scopus 로고
    • GRP78 induction in cancer: Therapeutic and prognostic implications
    • Lee AS: GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res 67: 3496-3499, 2007.
    • (2007) Cancer Res , vol.67 , pp. 3496-3499
    • Lee, A.S.1
  • 15
    • 7444240833 scopus 로고    scopus 로고
    • The ER function BiP is a master regulator of ER function
    • Hendershot LM: The ER function BiP is a master regulator of ER function. Mt Sinai J Med 71: 289-297, 2004.
    • (2004) Mt Sinai J Med , vol.71 , pp. 289-297
    • Hendershot, L.M.1
  • 16
    • 20444399528 scopus 로고    scopus 로고
    • Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance
    • DOI 10.1016/j.lungcan.2004.12.011, PII S0169500204006245
    • Uramoto H, Sugio K, Oyama T, Nakata S, Ono K, Yoshimastu T, Morita M, et al: Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance. Lung Cancer 49: 55-62, 2005. (Pubitemid 40798093)
    • (2005) Lung Cancer , vol.49 , Issue.1 , pp. 55-62
    • Uramoto, H.1    Sugio, K.2    Oyama, T.3    Nakata, S.4    Ono, K.5    Yoshimastu, T.6    Morita, M.7    Yasumoto, K.8
  • 18
    • 45049088225 scopus 로고    scopus 로고
    • Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas
    • Zheng HC, Takahashi H, Li XH, Hara T, Masuda S, Guan YF and Takano Y: Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas. Hum Pathol 39: 1042-1049, 2008.
    • (2008) Hum Pathol , vol.39 , pp. 1042-1049
    • Zheng, H.C.1    Takahashi, H.2    Li, X.H.3    Hara, T.4    Masuda, S.5    Guan, Y.F.6    Takano, Y.7
  • 19
    • 33750706551 scopus 로고    scopus 로고
    • Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer
    • DOI 10.1158/1078-0432.CCR-06-0133
    • Pootrakul L, Datar RH, Shi SR, Cai J, Hawes D, Groshen SG, Lee AS, et al: Expression of stress response protein GRP78 is associated with the development of castration-resistant prostate cancer. Clin Cancer Res 12: 5987-5993, 2006. (Pubitemid 44703758)
    • (2006) Clinical Cancer Research , vol.12 , Issue.20 PART 1 , pp. 5987-5993
    • Pootrakul, L.1    Datar, R.H.2    Shi, S.-R.3    Cai, J.4    Hawes, D.5    Groshen, S.G.6    Lee, A.S.7    Cote, R.J.8
  • 20
    • 32944457371 scopus 로고    scopus 로고
    • Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values
    • DOI 10.1002/pmic.200500306
    • Luk JM, Lam CT, Siu AFM, Lam BY, Ng IOL, Hu MY, Che CM, et al: Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values. Proteomics 6: 1049-1057, 2006. (Pubitemid 43260229)
    • (2006) Proteomics , vol.6 , Issue.3 , pp. 1049-1057
    • Luk, J.M.1    Lam, C.-T.2    Siu, A.F.M.3    Lam, B.Y.4    Ng, I.O.L.5    Hu, M.-Y.6    Che, C.-M.7    Fan, S.-T.8
  • 24
    • 79954569520 scopus 로고    scopus 로고
    • A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis
    • Dong DZ, Stapleton C, Luo BQ, Xiong SG, Ye W, Zhang Y, Jhaveri N, et al: A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Res 71: 2848-2857, 2011.
    • (2011) Cancer Res , vol.71 , pp. 2848-2857
    • Dong, D.Z.1    Stapleton, C.2    Luo, B.Q.3    Xiong, S.G.4    Ye, W.5    Zhang, Y.6    Jhaveri, N.7
  • 25
    • 78049490027 scopus 로고    scopus 로고
    • Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78
    • Katanasaka Y, Ishii T, Asai T, Naitou H, Maeda N, Koizumi F, Miyagawa S, et al: Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78. Int J Cancer 127: 2685-2698, 2010.
    • (2010) Int J Cancer , vol.127 , pp. 2685-2698
    • Katanasaka, Y.1    Ishii, T.2    Asai, T.3    Naitou, H.4    Maeda, N.5    Koizumi, F.6    Miyagawa, S.7
  • 26
    • 0027138875 scopus 로고
    • Suppression of stress protein GRP78 induction in tumor B/C10ME eliminates resistance to cell mediated cytotoxicity
    • Sugawara S, Takeda K, Lee A and Dennert G: Suppression of stress protein GRP78 induction in tumor B/C10ME eliminates resistance to cell mediated cytotoxicity. Cancer Res 53: 6001-6005, 1993. (Pubitemid 24006173)
    • (1993) Cancer Research , vol.53 , Issue.24 , pp. 6001-6005
    • Sugawara, S.1    Takeda, K.2    Lee, A.3    Dennert, G.4
  • 27
    • 77149157802 scopus 로고    scopus 로고
    • Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma
    • Chiou JF, Tai CJ, Huang MT, Wei PL, Wang YH, BS JA, Wu CH, et al: Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma. Ann Surg Oncol 17: 603-612, 2010.
    • (2010) Ann Surg Oncol , vol.17 , pp. 603-612
    • Chiou, J.F.1    Tai, C.J.2    Huang, M.T.3    Wei, P.L.4    Wang, Y.H.5    BS, J.A.6    Wu, C.H.7
  • 28
    • 0030948765 scopus 로고    scopus 로고
    • A lymphocyte cell surface heat shock protein homologgous to the endoplasmic reticulum chaprone, immunoglobulin heavy chain binding protein BIP
    • DOI 10.1002/(SICI)1097-0215(19970611)71:6<1077::AID-IJC26>3.0.CO;2- 9
    • Berger CL, Dong ZM, Hanlon D, Bisaccia E and Edelson RL: A lymphocyte cell surface heat shock protein homologous to the endoplasmic reticulum chaperone, immunoglobulin heavy chain binding protein BIP. Int J Cancer 71: 1077-1085, 1997. (Pubitemid 27252893)
    • (1997) International Journal of Cancer , vol.71 , Issue.6 , pp. 1077-1085
    • Berger, C.L.1    Dong, Z.2    Hanlon, D.3    Bisaccia, E.4    Edelson, R.L.5
  • 30
    • 4544255170 scopus 로고    scopus 로고
    • Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands
    • DOI 10.1016/j.ccr.2004.08.018, PII S1535610804002405
    • Arap MA, Lahdenranta J, Mintz PJ, Hajitou A, Sarkis AS, Arap W and Pasqualini R: Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands. Cancer Cell 6: 275-284, 2004. (Pubitemid 39222040)
    • (2004) Cancer Cell , vol.6 , Issue.3 , pp. 275-284
    • Arap, M.A.1    Lahdenranta, J.2    Mintz, P.J.3    Hajitou, A.4    Sarkis, A.S.5    Arap, W.6    Pasqualini, R.7
  • 32
    • 33845780561 scopus 로고    scopus 로고
    • Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum
    • DOI 10.1158/0008-5472.CAN-06-1721
    • Gonzalez-Gronow M, Cuchacovich M, Llanos C, Urzua C, Gawdi G and Pizzo SV: Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum. Cancer Res 66: 11424-11431, 2006. (Pubitemid 46009974)
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11424-11431
    • Gonzalez-Gronow, M.1    Cuchacovich, M.2    Llanos, C.3    Urzua, C.4    Gawdi, G.5    Pizzo, S.V.6
  • 33
    • 77949445585 scopus 로고    scopus 로고
    • Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer
    • Tsunemi S, Nakanishi T, Fujita Y, Bouras G, Miyamoto Y, MiyamotoI A, Nomura E, et al: Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer. Oncol Rep 23: 949-956, 2010.
    • (2010) Oncol Rep , vol.23 , pp. 949-956
    • Tsunemi, S.1    Nakanishi, T.2    Fujita, Y.3    Bouras, G.4    Miyamoto, Y.5    Miyamoto, I.A.6    Nomura, E.7
  • 34
    • 0031027946 scopus 로고    scopus 로고
    • 'Hepatoma-specific' alphafetoprotein may permit preclinical diagnosis of malignant change in patients with chronic liver disease
    • Johnson PJ, Leung N, Cheng P, Welby C, Leung WT, Lau WY, Yu S and Ho S: 'Hepatoma-specific' alphafetoprotein may permit preclinical diagnosis of malignant change in patients with chronic liver disease. Br J Cancer 75: 236-240, 1997.
    • (1997) Br J Cancer , vol.75 , pp. 236-240
    • Johnson, P.J.1    Leung, N.2    Cheng, P.3    Welby, C.4    Leung, W.T.5    Lau, W.Y.6    Yu, S.7    Ho, S.8
  • 35
    • 0001893076 scopus 로고    scopus 로고
    • Assessing the validity and reliability of diagnostic and screening tests
    • 2nd edition. W.B. Saunders Company, Philadelphia, PA
    • Gordis L (ed): Assessing the validity and reliability of diagnostic and screening tests. In: Epidemiology. 2nd edition. W.B. Saunders Company, Philadelphia, PA, pp63-81, 2000.
    • (2000) Epidemiology , pp. 63-81
    • Gordis, L.1
  • 36
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman RJ: Orchestrating the unfolded protein response in health and disease. J Clin Invest 110: 1389-1398, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 37
    • 34447558236 scopus 로고    scopus 로고
    • ER chaperones in mammalian development and human diseases
    • DOI 10.1016/j.febslet.2007.04.045, PII S0014579307004334, Cellular Stress
    • Ni M and Lee AS: ER chaperones in mammalian development and human diseases. FEBS Lett 581: 3641-3651, 2007. (Pubitemid 47082516)
    • (2007) FEBS Letters , vol.581 , Issue.19 , pp. 3641-3651
    • Ni, M.1    Lee, A.S.2
  • 38
    • 79952842932 scopus 로고    scopus 로고
    • The critical role of GRP78 in physiologic and pathologic stress
    • Pfaffenbach KT and Lee AS: The critical role of GRP78 in physiologic and pathologic stress. Curr Opin Cell Biol 23: 150-156, 2011.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 150-156
    • Pfaffenbach, K.T.1    Lee, A.S.2
  • 40
    • 22544456920 scopus 로고    scopus 로고
    • 2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK
    • DOI 10.1074/jbc.M414467200
    • Misra UK, Deedwania R and Pizzo SV: Binding of activated α2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. J Biol Chem 280: 26278-26286, 2005. (Pubitemid 41022225)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.28 , pp. 26278-26286
    • Misra, U.K.1    Deedwania, R.2    Pizzo, S.V.3
  • 41
    • 37849035474 scopus 로고    scopus 로고
    • GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor β signaling and enhance cell growth
    • Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W and Gray PC: GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor β signaling and enhance cell growth. Mol Cell Biol 28: 666-677, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 666-677
    • Shani, G.1    Fischer, W.H.2    Justice, N.J.3    Kelber, J.A.4    Vale, W.5    Gray, P.C.6
  • 42
    • 77956500946 scopus 로고    scopus 로고
    • Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores
    • Al-Hashimi AA, Caldwell J, Gonzalez-Gronow M, Pizzo SV, Aboumrad D, Pozza L, Al-Bayati H, et al: Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. J Biol Chem 285: 28912-28923, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 28912-28923
    • Al-Hashimi, A.A.1    Caldwell, J.2    Gonzalez-Gronow, M.3    Pizzo, S.V.4    Aboumrad, D.5    Pozza, L.6    Al-Bayati, H.7
  • 43
    • 67649256065 scopus 로고    scopus 로고
    • Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways
    • Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW and Gray PC: Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways. Oncogene 28: 2324-2336, 2009.
    • (2009) Oncogene , vol.28 , pp. 2324-2336
    • Kelber, J.A.1    Panopoulos, A.D.2    Shani, G.3    Booker, E.C.4    Belmonte, J.C.5    Vale, W.W.6    Gray, P.C.7
  • 44
    • 79951537603 scopus 로고    scopus 로고
    • Beyond the endoplasmic reticulum: Atypical GRP78 in cell viability, signalling and therapeutic targeting
    • Ni M, Zhang Y and Lee AS: Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting. Biochem J 434: 181-188, 2011.
    • (2011) Biochem J , vol.434 , pp. 181-188
    • Ni, M.1    Zhang, Y.2    Lee, A.S.3
  • 45
    • 85046915739 scopus 로고    scopus 로고
    • Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells
    • Misra UK and Pizzo AV: Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells. Cancer Biol Ther 9: 1-11, 2010.
    • (2010) Cancer Biol Ther , vol.9 , pp. 1-11
    • Misra, U.K.1    Pizzo, A.V.2
  • 46
    • 66849083879 scopus 로고    scopus 로고
    • Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis
    • Misra UK, Mowery Y, Kaczowka S and Pizzo SV: Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis. Mol Cancer Ther 8: 1350-1362, 2009.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1350-1362
    • Misra, U.K.1    Mowery, Y.2    Kaczowka, S.3    Pizzo, S.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.