Age-related changes in the diurnal rhythm of CRH gene expression in the paraventricular nuclei

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 2 33-2, 1996, Pages

  Cai, Aihua ^a   Wise, Phyllis M ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

aging; female rats; in situ hybridization; suprachiasmatic nucleus

Indexed keywords

CORTICOTROPIN RELEASING FACTOR;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORTICOTROPIN RELEASE; FEMALE; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RAT; SUPRACHIASMATIC NUCLEUS;

EID: 0029923410     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.2.e238     Document Type: Article

References (35)

1. Bagdy, G., G. P. Chrousos, and A. E. Calogero. Circadian patterns of plasma immunoreactive corticotropin, beta-endorphin, corticosterone and prolactin after immunoneutralization of corticotropin-releasing hormone. Neuroendocrinology 53: 573-578, 1991.
2. Brock, M. A. Chronobiology, and aging. J. Am. Geriatr. Soc. 39: 74-91, 1991.
3. Buijs, R. M., M. Markman, B. Nunes-Cardoso, Y.-X. Hou, and S. Shinn. Projections of the suprachiasmatic nucleus to stress-related areas in the rat hypothalamus: a light and electron microscopic study. J. Comp. Neurol. 335: 42-54, 1993.
4. Carnes, M., B. M. Goodman, S. J. Lent, and H. Vo. High intensity venous sampling reveals subtle alterations in plasma adrenocorticotropin patterns in old rats. Endocrinology 133: 608-616, 1993.
5. Carnes, M., S. J. Lent, S. Erisman, C. Barksdale, and J. Feyzi. Immunoneutralization of corticotropin-releasing hormone prevents the diurnal surge of ACTH. Life Sci. 45: 1049-1056, 1989.
6. Cizza, G., A. E. Calogero, L. S. Brady, G. Bagdy, E. Bergamini, M. R. Blackman, G. P. Chrousos, and P. W. Gold. Male Fischer 344/N rats show a progressive central impairment of the hypothalamic-pituitary-adrenal axis with advancing age. Endocrinology 134: 1611-1620, 1994.
7. Goya, R. G., M. G. Castro, and Y. E. Sosa. Diminished diurnal secretion of corticosterone in aging female but not male rats. Gerontology 35: 181-187, 1989.
8. Hermes, M. L. H. J., and L. P. Renaud. Differential responses of identified rat hypothalamic paraventricular neurons to suprachiasmatic nucleus stimulation. Neuroscience 56: 823-832, 1993.
9. Heroux, J. A., D. E. Grigoriadis, and E. B. De Souza. Age-related decreases in corticotropin-releasing factor (CRF) receptors in rat brain and anterior pituitary gland. Brain Res. 542: 155-158, 1991.
10. Heuser, I. J. E., H.-J. Wark, J. Keul, and F. Holsboer. Hypothalamic-pituitary-adrenal axis function in elderly endurance athletes. J. Clin. Endocrinol. Metab. 73: 485-488, 1991.
11. Kaneko, M., K. Kaneko, J. Shinsako, and M. F. Dallman. Adrenal sensitivity to adrenocorticotropin varies diurnally. Endocrinology 109: 70-75, 1981.
12. Konig, J. F. R., and R. A. Klippel. The, Rat Brain. A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brain Stem. Huntington, WV: Krieger, 1963, p. 1-162.
13. Kowalski, C., J. Micheau, R. Corder, R. Gaillard, and B. Conte-Devolx. Age-related changes in cortico-releasing factor, somatostatin, neuropeptide Y, methionine enkephalin and beta-endorphin in specific rat brain areas. Brain Res. 582: 38-46, 1992.
14. Kwak, S. P., M. I. Morano, E. A. Young, S. J. Watson, and H. Akil. Diurnal CRH mRNA rhythm in the hypothahnus: decreased expression in the evening is not dependent on endogenous glucocorticoids. Neuroendocrinology 57: 96-105, 1993.
15. Kwak, S. P., E. A. Young, I. Morano, S. J. Watson, and H. Akil. Diurnal corticotropin-releasing hormone mRNA variation in the hypothalamus exhibits a rhythm distinct from that of plasma corticosterone. Neuroendocrinology 55: 74-83, 1992.
16. Meaney, M. J., D. H. Aitken, S. Sharma, and V. Viau. Basal ACTH, corticosterone and corticosterone-binding globulin levels over the diurnal cycle, and age-related changes in hippocampal type I and type II corticosteroid receptor binding capacity in young and aged, handled and nonhandled rats. Neuroendocrinology 55: 204-213, 1992.
17. Mirmiran, M., D. F. Swaab, J. H. Kok, M. A. Hofman, W. Witting, and W. A. Van Gool. Circadian rhythms and the suprachiasmatic nucleus in perinatal development, aging and Alzheimer's disease. Prog. Brain Res. 93: 151-163, 1992.
18. Moldow, R. L., and A. J. Fischman. Circadian rhythm of corticotropin releasing factor-like immunoreactivity in rat hypothalamus. Peptides 5: 1213-1215, 1984.
19. Nicholson, S., J.-H. Lin, S. Mahmoud, E. Campbell, B. Gilham, and M. Jones. Diurnal variations in responsiveness of the hypothalamo-pituitary-adrenocortical axis of the rat. Neuroendocrinology 40: 217-224, 1985.
20. Owens, M. J., J. Bartolome, S. M. Schanberg, and C. B. Nemeroff. Corticotropin-releasing factor concentrations exhibit an apparent diurnal rhythm in hypothalamic and extrahypothalamic brain regions: differential sensitivity to corticosterone. Neuroendocrinology 52: 626-631, 1990.
21. Oxenkrug, G. F., I. M. McIntyre, and S. Gershon. Effects of pinealectomy and aging on serum corticosterone circadian rhythm in rats. J. Pineal. Res. 1: 181-185, 1984.
22. Sapolsky, R. M. Do glucocorticoid concentrations rise with age in the rat? Neurobiol. Aging 13: 171-174, 1991.
23. Seeman, T. E., and R. J. Robbins. Aging and hypothalamic-pituitary-adrenal response to challenge in humans. Endocr. Rev. 15: 233-260, 1994.
24. Sherman, B., C. Wysham, and B. Pfohl. Age-related changes in the circadian rhythm of plasma cortisol in man. J. Clin. Endocrinol. Metab. 61: 439-443, 1985.
25. Sonntag, W. E., A. G. Goliszek, A. Brodish, and J. C. Eldridge. Diminished diurnal secretion of adrenocorticotropin (ACTH), but not corticosterone, in old male rats: possible relation to increased adrenal sensitivity to ACTH in vivo. Endocrinology 120: 2308-2315, 1987.
26. Swanson, L. W., and H. G. J. M. Kuypers. The paraventricular nucleus of the hypothalamus: cytoarchitectonic subdivisions and organization of projections to the pituitary, dorsal vagal complex, and spinal cord as demonstrated by retrograde fluorescence double-labeling methods. J. Comp. Neurol. 194: 555-570, 1980.
27. Swanson, L. W., P. E. Sawchenko, and R. W. Lind. Regulation of multiple peptides in CRF parvocellular neurosecretory neurons; implications for the stress response. In: Progress in Brain Research, edited by T. Hokfelt, K. Fuxe, and B. Pernow. New York: Elsevier, 1986, p. 169-190.
28. Swanson, L. W., and D. M. Simmons. Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat. J. Comp. Neurol. 285: 413-435, 1989.
29. Szafarczyk, A., M. Hery, E. Laplante, G. Ixart, I. Assenmacher, and C. Kordon. Temporal relationships between the circadian rhythmicity in plasma levels of pituitary hormones and in hypothalamie concentrations of releasing factors. Neuroendocrinology 30: 369-376, 1980.
30. Szafarczyk, A., G. Ixart, F. Malaval, J. Nouguier-Soule, and I. Assenmacher. Effects of lesions of the suprachiasmatic nuclei and of p-chlorophenylalanine on the circadian rhythms of adrenocorticotrophic hormone and corticosterone in the plasma, and on locomotor activity of rats. J. Endocrinol. 83: 1-16, 1979.
31. Watts, A. G., and L. W. Swanson. Diurnal variations in the content of preprocorticotropin-releasing hormone messenger ribo-nucleic acids in the hypothalamic paraventricular nucleus of rats of both sexes as measured by in situ hybridization. Endocrinology 125: 1734-1738, 1989.
32. Weiland, N. G., K. Scarbrough, and P. M. Wise. Aging abolishes the estradiol-induced suppression and diurnal rhythm of proopiomelanocortin gene expression in the arcuate nucleus. Endocrinology 131: 2959-2964, 1992.
33. Wise, P. M. Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats. Proc. Soc. Exp. Biol. Med. 169: 348-354, 1982.
34. Wise, P. M., I. R. Cohen, N. G. Weiland, and E. D. London. Aging alters the circadian rhythm of glucose utilization in the suprachiasmatic nucleus. Proc. Natl. Acad. Sci. USA 85: 5305-5309, 1988.
35. Wise, P. M., K. Scarbrough, J. Lloyd, A. Cai, J. Harney, S. Chiu, D. Hinkle, and T. McShane. Neuroendocrine concomitants of reproductive aging. Exp. Gerontol. 29: 275-283, 1994.