OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance

Biochemical Pharmacology

Volumn 84, Issue 6, 2012, Pages 766-774

  Kuang, Ye Hong ^a,b   Patel, Jay P ^a   Sodani, Kamlesh ^a   Wu, Chung Pu ^c   Liao, Li Qiu ^b   Patel, Atish ^a   Tiwari, Amit K ^a   Dai, Chun Ling ^a,d   Chen, Xiang ^b   Fu, Li Wu ^d   Ambudkar, Suresh V ^c   Korlipara, Vijaya L ^a   Chen, Zhe Sheng ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SUN YAT SEN UNIVERSITY   (China)

Author keywords

ABC transporters; ABCG2; Multidrug resistance; OSI 930

Indexed keywords

2 AMINOBENZAMIDE; ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CISPLATIN; DOXORUBICIN; FIRTECAN; FUMITREMORGIN C; MITOXANTRONE; OSI 930; PAK 104; UNCLASSIFIED DRUG; VERAPAMIL; VKJP 1; VKJP 10; VKJP 11; VKJP 12; VKJP 13; VKJP 14; VKJP 15; VKJP 2; VKJP 3; VKJP 4; VKJP 5; VKJP 6; VKJP 7; VKJP 8; VKJP 9;

ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CONTROLLED STUDY; DRUG BINDING SITE; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; AZIDES; BENZENE DERIVATIVES; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MITOXANTRONE; NEOPLASM PROTEINS; NITRO COMPOUNDS; PHOTOAFFINITY LABELS; PRAZOSIN; PYRIDINES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES; TRANSFECTION;

EID: 84864944160     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.06.019     Document Type: Article

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