Designing optimal cell factories: Integer programming couples elementary mode analysis with regulation

BMC Systems Biology

Volumn 6, Issue , 2012, Pages

  Jungreuthmayer, Christian ^a,b   Zanghellini, Jürgen ^a,b  

^a AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

Elementary modes; Ethanol production; Gene regulation; Integer programming; Metabolic engineering; Minimal cut sets; Minimal functionality; Strain optimization

Indexed keywords

ESCHERICHIA COLI;

ALCOHOL;

ARTICLE; BIOLOGICAL MODEL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLIC ENGINEERING; METABOLISM; METHODOLOGY; REPRODUCIBILITY; STATISTICAL MODEL;

ESCHERICHIA COLI; ETHANOL; GENE EXPRESSION REGULATION; LINEAR MODELS; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; TRANSCRIPTION, GENETIC;

MLCS; MLOWN;

EID: 84864923763     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-6-103     Document Type: Article

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