Mitochondrial ROS production and subsequent ERK phosphorylation are necessary for temperature preconditioning of isolated ventricular myocytes

Cell Death and Disease

Volumn 3, Issue 7, 2012, Pages

  Bhagatte, Y ^a   Lodwick, D ^a   Storey, N ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

cardiac; cardioprotection; ERK; hypothermia; ischaemia reperfusion; preconditioning

Indexed keywords

MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; TIOPRONIN; CARRIER PROTEIN; DRUG DERIVATIVE; GLYCINE; MITOGEN ACTIVATED PROTEIN KINASE; N (2 MERCAPTOPROPRIONYL) GLYCINE; N-(2-MERCAPTOPROPRIONYL)-GLYCINE; SCAVENGER; THIOL DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSENSOR; CALCIUM HOMEOSTASIS; CELL FUNCTION; CELL ISOLATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; HEART VENTRICLE; INDUCED HYPOTHERMIA; MALE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TEMPERATURE; ANIMAL; CELL CULTURE; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WISTAR RAT;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; GLYCINE; MALE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; PHOSPHORYLATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SULFHYDRYL COMPOUNDS; TEMPERATURE;

EID: 84864874840     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.84     Document Type: Article

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