-
2
-
-
84862765265
-
Unraveling the genetic component of systemic sclerosis
-
Martin JE, Bossini-Castillo L, Martin J. Unraveling the genetic component of systemic sclerosis. Hum Genet 2012:131: 1023-37.
-
(2012)
Hum Genet
, vol.131
, pp. 1023-1037
-
-
Martin, J.E.1
Bossini-Castillo, L.2
Martin, J.3
-
3
-
-
17644368573
-
Interleukin-6: from basic science to medicine-40years in immunology
-
Kishimoto T. Interleukin-6: from basic science to medicine-40years in immunology. Annu Rev Immunol. 2005: 23: 1-21.
-
(2005)
Annu Rev Immunol.
, vol.23
, pp. 1-21
-
-
Kishimoto, T.1
-
4
-
-
81555209757
-
The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis
-
Barnes TC, Anderson ME, Moots RJ. The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis. Int J Rheumatol 2011: 2011: 721608.
-
(2011)
Int J Rheumatol
, vol.2011
, pp. 721608
-
-
Barnes, T.C.1
Anderson, M.E.2
Moots, R.J.3
-
5
-
-
0032189103
-
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
-
Fishman D, Faulds G, Jeffery R et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998: 102: 1369-76.
-
(1998)
J Clin Invest
, vol.102
, pp. 1369-1376
-
-
Fishman, D.1
Faulds, G.2
Jeffery, R.3
-
6
-
-
34548169544
-
No evidence for a role of the proximal IL-6G/C -174 single nucleotide polymorphism in Italian patients with systemic sclerosis
-
Beretta L, Santaniello A, Cappiello F, Barili M, Scorza R. No evidence for a role of the proximal IL-6G/C -174 single nucleotide polymorphism in Italian patients with systemic sclerosis. J Cell Mol Med 2007: 11: 896-8.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 896-898
-
-
Beretta, L.1
Santaniello, A.2
Cappiello, F.3
Barili, M.4
Scorza, R.5
-
7
-
-
0035164602
-
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
-
Jones SA, Horiuchi S, Topley N, Yamamoto N, Fuller GM. The soluble interleukin 6 receptor: mechanisms of production and implications in disease. FASEB J 2001: 15: 43-58.
-
(2001)
FASEB J
, vol.15
, pp. 43-58
-
-
Jones, S.A.1
Horiuchi, S.2
Topley, N.3
Yamamoto, N.4
Fuller, G.M.5
-
8
-
-
0029830133
-
Increased serum concentrations of interleukin-6 (IL-6) and soluble IL-6 receptor in patients with Graves' disease
-
Salvi M, Girasole G, Pedrazzoni M et al. Increased serum concentrations of interleukin-6 (IL-6) and soluble IL-6 receptor in patients with Graves' disease. J Clin Endocrinol Metab 1996: 81: 2976-9.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 2976-2979
-
-
Salvi, M.1
Girasole, G.2
Pedrazzoni, M.3
-
9
-
-
0028796711
-
Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6
-
Mitsuyama K, Toyonaga A, Sasaki E et al. Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6. Gut 1995: 36: 45-9.
-
(1995)
Gut
, vol.36
, pp. 45-49
-
-
Mitsuyama, K.1
Toyonaga, A.2
Sasaki, E.3
-
10
-
-
0032731374
-
CSF and serum levels of soluble interleukin-6 receptors (sIL-6R and sgp130), but not of interleukin-6 are altered in multiple sclerosis
-
Padberg F, Feneberg W, Schmidt S et al. CSF and serum levels of soluble interleukin-6 receptors (sIL-6R and sgp130), but not of interleukin-6 are altered in multiple sclerosis. J Neuroimmunol 1999: 99: 218-23.
-
(1999)
J Neuroimmunol
, vol.99
, pp. 218-223
-
-
Padberg, F.1
Feneberg, W.2
Schmidt, S.3
-
11
-
-
0028270409
-
The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site
-
Mullberg J, Oberthur W, Lottspeich F et al. The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site. J Immunol 1994: 152: 4958-68.
-
(1994)
J Immunol
, vol.152
, pp. 4958-4968
-
-
Mullberg, J.1
Oberthur, W.2
Lottspeich, F.3
-
12
-
-
9444245832
-
Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites
-
Hamid YH, Urhammer SA, Jensen DP et al. Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites. Diabetes 2004: 53: 3342-5.
-
(2004)
Diabetes
, vol.53
, pp. 3342-3345
-
-
Hamid, Y.H.1
Urhammer, S.A.2
Jensen, D.P.3
-
13
-
-
36849038962
-
Interleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 diabetes in U.S. Women
-
Qi L, Rifai N, Hu FB. Interleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 diabetes in U.S. Women. Diabetes 2007: 56: 3075-81.
-
(2007)
Diabetes
, vol.56
, pp. 3075-3081
-
-
Qi, L.1
Rifai, N.2
Hu, F.B.3
-
14
-
-
79954435661
-
Plasma soluble IL-6 receptor concentration in rheumatoid arthritis: associations with the rs8192284 IL6R polymorphism and with disease activity
-
Rodriguez-Rodriguez L, Lamas JR, Varade J et al. Plasma soluble IL-6 receptor concentration in rheumatoid arthritis: associations with the rs8192284 IL6R polymorphism and with disease activity. Rheumatol Int 2011: 31: 409-13.
-
(2011)
Rheumatol Int
, vol.31
, pp. 409-413
-
-
Rodriguez-Rodriguez, L.1
Lamas, J.R.2
Varade, J.3
-
15
-
-
0032746822
-
Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
-
Hasegawa M, Sato S, Ihn H, Takehara K. Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. Rheumatology (Oxford) 1999: 38: 612-17.
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 612-617
-
-
Hasegawa, M.1
Sato, S.2
Ihn, H.3
Takehara, K.4
-
16
-
-
38149030116
-
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
-
Benrick A, Jirholt P, Wernstedt I et al. A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population. Regul Pept 2008: 146: 189-96.
-
(2008)
Regul Pept
, vol.146
, pp. 189-196
-
-
Benrick, A.1
Jirholt, P.2
Wernstedt, I.3
-
17
-
-
0018887574
-
-
Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 1980: 23: 581-90.
-
Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 1980: 23: 581-90.
-
-
-
-
18
-
-
0023854176
-
Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
-
LeRoy EC, Black C, Fleischmajer R et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988: 15: 202-5.
-
(1988)
J Rheumatol
, vol.15
, pp. 202-205
-
-
LeRoy, E.C.1
Black, C.2
Fleischmajer, R.3
-
19
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007: 81: 559-75.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
20
-
-
31744435871
-
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
-
Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 2006: 38: 209-13.
-
(2006)
Nat Genet
, vol.38
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
Boehnke, M.4
-
21
-
-
61349095927
-
The IL6-174G/C polymorphism is associated with celiac disease susceptibility in girls
-
Dema B, Martinez A, Fernandez-Arquero M et al. The IL6-174G/C polymorphism is associated with celiac disease susceptibility in girls. Hum Immunol 2009: 70: 191-4.
-
(2009)
Hum Immunol
, vol.70
, pp. 191-194
-
-
Dema, B.1
Martinez, A.2
Fernandez-Arquero, M.3
-
22
-
-
0024323330
-
A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor beta the answer?
-
Leroy EC, Smith EA, Kahaleh MB, Trojanowska M, Silver RM. A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor beta the answer? Arthritis Rheum 1989: 32: 817-25.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 817-825
-
-
Leroy, E.C.1
Smith, E.A.2
Kahaleh, M.B.3
Trojanowska, M.4
Silver, R.M.5
-
23
-
-
0025989368
-
Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6
-
Duncan MR, Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6. J Invest Dermatol 1991: 97: 686-92.
-
(1991)
J Invest Dermatol
, vol.97
, pp. 686-692
-
-
Duncan, M.R.1
Berman, B.2
-
24
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova A, van Diemen CC, Wijmenga C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009: 10: 43-55.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
van Diemen, C.C.2
Wijmenga, C.3
-
25
-
-
79955974107
-
Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis
-
Fenoglio D, Battaglia F, Parodi A et al. Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis. Clin Immunol 2011: 139: 249-57.
-
(2011)
Clin Immunol
, vol.139
, pp. 249-257
-
-
Fenoglio, D.1
Battaglia, F.2
Parodi, A.3
-
26
-
-
36549048990
-
Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma
-
Deleuran B, Abraham DJ. Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma. Nat Clin Pract Rheumatol 2007: 3: 682-3.
-
(2007)
Nat Clin Pract Rheumatol
, vol.3
, pp. 682-683
-
-
Deleuran, B.1
Abraham, D.J.2
-
27
-
-
78049421175
-
The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
-
Shima Y, Kuwahara Y, Murota H et al. The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab. Rheumatology (Oxford) 2010: 49: 2408-12.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 2408-2412
-
-
Shima, Y.1
Kuwahara, Y.2
Murota, H.3
-
28
-
-
77951765348
-
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
-
Radstake TR, Gorlova O, Rueda B et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 2010: 42: 426-9.
-
(2010)
Nat Genet
, vol.42
, pp. 426-429
-
-
Radstake, T.R.1
Gorlova, O.2
Rueda, B.3
-
29
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini J, Howie B, Myers S, McVean G, Donnelly P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 2007: 39: 906-13.
-
(2007)
Nat Genet
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
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