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Volumn 424, Issue 4, 2012, Pages 801-806

Oncostatin M inhibits TGF-β1-induced CTGF expression via STAT3 in human proximal tubular cells

Author keywords

CTGF; Oncostatin M; Proximal tubular epithelial cells; SMAD3; STAT3; TGF 1

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; ONCOSTATIN M; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; STAT1 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84864810816     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.042     Document Type: Article
Times cited : (21)

References (28)
  • 1
    • 0036775425 scopus 로고    scopus 로고
    • Matricellular proteins: extracellular modulators of cell function
    • Bornstein P., Sage E.H. Matricellular proteins: extracellular modulators of cell function. Curr. Opin. Cell Biol. 2002, 14:608-616.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 608-616
    • Bornstein, P.1    Sage, E.H.2
  • 2
    • 82455198983 scopus 로고    scopus 로고
    • Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
    • Jun J.I., Lau L.F. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat. Rev. Drug Discovery 2011, 10:945-963.
    • (2011) Nat. Rev. Drug Discovery , vol.10 , pp. 945-963
    • Jun, J.I.1    Lau, L.F.2
  • 3
    • 20444504753 scopus 로고    scopus 로고
    • Structural and functional properties of CCN proteins
    • Rachfal A.W., Brigstock D.R. Structural and functional properties of CCN proteins. Vitam. Horm. 2005, 70:69-103.
    • (2005) Vitam. Horm. , vol.70 , pp. 69-103
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 4
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(CTGF, CCN2)-a marker, mediator and therapeutic target for renal fibrosis
    • Phanish M.K., Winn S.K., Dockrell M.E.C. Connective tissue growth factor-(CTGF, CCN2)-a marker, mediator and therapeutic target for renal fibrosis. Nephron Exp. Nephrol. 2010, 114:e83-e92.
    • (2010) Nephron Exp. Nephrol. , vol.114
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.C.3
  • 5
    • 13444250205 scopus 로고    scopus 로고
    • Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point?
    • van Nieuwenhoven F.A., Jensen L.J.N., Flyvbjerg A., Goldschmeding R. Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point?. Nephrol. Dial. Transplant. 2005, 20:6-10.
    • (2005) Nephrol. Dial. Transplant. , vol.20 , pp. 6-10
    • van Nieuwenhoven, F.A.1    Jensen, L.J.N.2    Flyvbjerg, A.3    Goldschmeding, R.4
  • 7
    • 28444461820 scopus 로고    scopus 로고
    • Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli
    • Wahab N.A., Schaefer L., Weston B.S., Yiannikouris O., Wright A., Babelova A., Schaefer R., Mason R.M. Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli. Diabetologia 2005, 48:2650-2660.
    • (2005) Diabetologia , vol.48 , pp. 2650-2660
    • Wahab, N.A.1    Schaefer, L.2    Weston, B.S.3    Yiannikouris, O.4    Wright, A.5    Babelova, A.6    Schaefer, R.7    Mason, R.M.8
  • 8
    • 0033957976 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
    • Riser B.L., Denichilo M., Cortes P., Baker C., Grondin J.M., Yee J., Narins R.G. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J. Am. Soc. Nephrol. 2000, 11:25-38.
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 25-38
    • Riser, B.L.1    Denichilo, M.2    Cortes, P.3    Baker, C.4    Grondin, J.M.5    Yee, J.6    Narins, R.G.7
  • 9
    • 0035190222 scopus 로고    scopus 로고
    • Glomerular mRNAs in human type 1 diabetes: biochemical evidence for microalbuminuria as a manifestation of diabetic nephropathy
    • Adler S.G., Kang S.W., Feld S., Cha D.R., Barba L., Striker L., Striker G., Riser B.L., LaPage J., Nast C.C. Glomerular mRNAs in human type 1 diabetes: biochemical evidence for microalbuminuria as a manifestation of diabetic nephropathy. Kidney Int. 2001, 60:2330-2336.
    • (2001) Kidney Int. , vol.60 , pp. 2330-2336
    • Adler, S.G.1    Kang, S.W.2    Feld, S.3    Cha, D.R.4    Barba, L.5    Striker, L.6    Striker, G.7    Riser, B.L.8    LaPage, J.9    Nast, C.C.10
  • 10
    • 0034951422 scopus 로고    scopus 로고
    • Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy
    • Wang S., Denichilo M., Brubaker C., Hirschberg R. Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy. Kidney Int. 2001, 60:96-105.
    • (2001) Kidney Int. , vol.60 , pp. 96-105
    • Wang, S.1    Denichilo, M.2    Brubaker, C.3    Hirschberg, R.4
  • 11
    • 35248841125 scopus 로고    scopus 로고
    • Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
    • Guha M., Xu Z.G., Tung D., Lanting L., Natarajan R. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. FASEB J. 2007, 21:3355-3368.
    • (2007) FASEB J. , vol.21 , pp. 3355-3368
    • Guha, M.1    Xu, Z.G.2    Tung, D.3    Lanting, L.4    Natarajan, R.5
  • 16
    • 33644875787 scopus 로고    scopus 로고
    • Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy
    • Nguyen T.Q., Tarnow L., Andersen S., Hovind P., Parving H.H., Goldschmeding R., van Nieuwenhoven F.A. Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care 2006, 29:83-88.
    • (2006) Diabetes Care , vol.29 , pp. 83-88
    • Nguyen, T.Q.1    Tarnow, L.2    Andersen, S.3    Hovind, P.4    Parving, H.H.5    Goldschmeding, R.6    van Nieuwenhoven, F.A.7
  • 18
    • 73549119945 scopus 로고    scopus 로고
    • Connective tissue growth factor (CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?
    • Mason R.M. Connective tissue growth factor (CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?. J. Cell. Commun. Signal 2009, 3:95-104.
    • (2009) J. Cell. Commun. Signal , vol.3 , pp. 95-104
    • Mason, R.M.1
  • 19
    • 0027229995 scopus 로고
    • Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
    • Igarashi A., Okochi H., Bradham D.M., Grotendorst G.R. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol. Biol. Cell 1993, 4:637-645.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 637-645
    • Igarashi, A.1    Okochi, H.2    Bradham, D.M.3    Grotendorst, G.R.4
  • 20
    • 0033802165 scopus 로고    scopus 로고
    • Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis
    • Gupta S., Clarkson M.R., Duggan J., Brady H.R. Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. Kidney Int. 2000, 58:1389-1399.
    • (2000) Kidney Int. , vol.58 , pp. 1389-1399
    • Gupta, S.1    Clarkson, M.R.2    Duggan, J.3    Brady, H.R.4
  • 21
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts
    • Grotendorst G.R. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 1997, 8:171-179.
    • (1997) Cytokine Growth Factor Rev. , vol.8 , pp. 171-179
    • Grotendorst, G.R.1
  • 24
    • 80052754775 scopus 로고    scopus 로고
    • Diverse roles of TGF-β/Smads in renal fibrosis and inflammation
    • Lan H.Y. Diverse roles of TGF-β/Smads in renal fibrosis and inflammation. Int. J. Biol. Sci. 2011, 7:1056-1067.
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 1056-1067
    • Lan, H.Y.1
  • 25
    • 84859413955 scopus 로고    scopus 로고
    • Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects
    • López-Hernández F.J., López-Novoa J.M. Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects. Cell Tissue Res. 2012, 347:141-154.
    • (2012) Cell Tissue Res. , vol.347 , pp. 141-154
    • López-Hernández, F.J.1    López-Novoa, J.M.2
  • 26
    • 2542609844 scopus 로고    scopus 로고
    • Smad3 as a mediator of the fibrotic response
    • Flanders K.C. Smad3 as a mediator of the fibrotic response. Int. J. Exp. Pathol. 2004, 85:47-64.
    • (2004) Int. J. Exp. Pathol. , vol.85 , pp. 47-64
    • Flanders, K.C.1
  • 27
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M., Muragaki Y., Saika S., Roberts A.B., Ooshima A. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J. Clin. Invest. 2003, 112:1486-1494.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 28
    • 84864312353 scopus 로고    scopus 로고
    • TGF-β/Smad signaling in diabetic nephropathy
    • Lan H.Y. TGF-β/Smad signaling in diabetic nephropathy. Clin. Exp. Pharmacol. Physiol. 2011 Dec 28, 10.1111/j.1440-1681.2011.05663.x.
    • (2011) Clin. Exp. Pharmacol. Physiol.
    • Lan, H.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.