Glomerular mRNAS in human type 1 diabetes: Biochemical evidence for microalbuminuria as a manifestation of diabetic nephropathy

Kidney International

Volumn 60, Issue 6, 2001, Pages 2330-2336

  Adler, S G ^a,b,c   Kang, S W ^a,b,c   Feld, S ^a,b,c   Dae Ryong Cha, ^a,b,c   Barba, L ^a,b,c   Striker, L ^a,b,c   Striker, G ^a,b,c   Riser, B L ^a,b,c   LaPage, J ^a,b,c   Nast, C C ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c HENRY FORD HOSPITAL   (United States)

Author keywords

Connective tissue growth factor; Diabetic nephropathy; Mesangial expansion; Type 1 diabetes; Type IV collagen

Indexed keywords

COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; CREATININE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA;

ADULT; ARTICLE; BIOCHEMISTRY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; DONOR; GLOMERULUS; HUMAN; HUMAN TISSUE; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BIOPSY; KIDNEY GRAFT; MESANGIUM; MICROALBUMINURIA; PRIORITY JOURNAL; PROTEINURIA;

EID: 0035190222     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.00073.x     Document Type: Article

References (21)

1. Predicting diabetic nephropathy in insulin-dependent patients
2. Early detection of patients at risk of developing diabetic nephropathy. A prospective study of urinary albumin excretion
3. Incipient nephropathy in type 1 (insulin-dependent) diabetes
4. Glomerular lesions and urinary albumin excretion in type I diabetes without overt proteinuria
5. Glomerular structure in nonproteinuric IDDM patients with various levels of albuminuria
6. Prognostic significance of albuminuria for the development of nephropathy
7. Molecular analysis of glomerular diseases in renal biopsies: Initial results of a collaborative international study
8. Glomerular type IV collagen in patients with diabetic nephropathy with and without additional glomerular disease
9. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
10. ECM gene expression and its modulation by insulin in diabetic rats
11. Altered steady-state mRNA levels of basement membrane proteins in diabetic mouse kidneys and thromboxane synthase inhibition
12. Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes
13. Glomerular distribution of type IV collagen in diabetes by high resolution quantitative immunochemistry
14. Polyantigenic expansion of basement membrane constituents in diabetic nephropathy
15. In situ localization of type II and type IV collagen-expression cells in human diabetic nephropathy
16. Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions
17. Expression of glomerular extracellular matrix components in human diabetic nephropathy: Decrease of heparan sulphate in the glomerular basement membrane
18. Changes in glomerular extracellular matrices components in diabetic nephropathy
19. Diabetic glomerulosclerosis-immunogold ultrastructural studies on the glomerular distribution of type IV collagen and heparan sulphate proteoglycan
20. Glomerular transforming growth factor-beta1 mRNA as a marker of glomerulosclerosis-application in renal biopsies
21. Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: Down-regulation by cAMP