-
2
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM (2011) Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479: 232-236
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
van de Sluis, B.6
Kirkland, J.L.7
van Deursen, J.M.8
-
3
-
-
84864823834
-
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
-
DOI 10.1002/emmm.201200245
-
Bernardes de Jesus B, Vera E, Schneeberger K, Tejera AM, Ayuso E, Bosch F, Blasco MA (2012) Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO Mol Med DOI 10.1002/emmm.201200245
-
(2012)
EMBO Mol Med
-
-
Bernardes de Jesus, B.1
Vera, E.2
Schneeberger, K.3
Tejera, A.M.4
Ayuso, E.5
Bosch, F.6
Blasco, M.A.7
-
4
-
-
40349085766
-
The longest telomeres: a general signature of adult stem cell compartments
-
Flores I, Canela A, Vera E, Tejera A, Cotsarelis G, Blasco MA (2008) The longest telomeres: a general signature of adult stem cell compartments. Genes Dev 22: 654-667
-
(2008)
Genes Dev
, vol.22
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
5
-
-
84859372986
-
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
-
DOI: 10.1038/ncb2466
-
Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, et al (2012) Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat Cell Biol DOI: 10.1038/ncb2466
-
(2012)
Nat Cell Biol
-
-
Fumagalli, M.1
Rossiello, F.2
Clerici, M.3
Barozzi, S.4
Cittaro, D.5
Kaplunov, J.M.6
Bucci, G.7
Dobreva, M.8
Matti, V.9
Beausejour, C.M.10
-
6
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
Gonzalez-Suarez E, Samper E, Ramirez A, Flores JM, Martin-Caballero J, Jorcano JL, Blasco MA (2001) Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 20: 2619-2630
-
(2001)
EMBO J
, vol.20
, pp. 2619-2630
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Ramirez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
-
8
-
-
84859352385
-
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
-
Hewitt G, Jurk D, Marques FD, Correia-Melo C, Hardy T, Gackowska A, Anderson R, Taschuk M, Mann J, Passos JF (2012) Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nat Commun 3: 708
-
(2012)
Nat Commun
, vol.3
, pp. 708
-
-
Hewitt, G.1
Jurk, D.2
Marques, F.D.3
Correia-Melo, C.4
Hardy, T.5
Gackowska, A.6
Anderson, R.7
Taschuk, M.8
Mann, J.9
Passos, J.F.10
-
9
-
-
79953088521
-
Assessing the potential for AAV vector genotoxicity in a murine model
-
Li H, Malani N, Hamilton SR, Schlachterman A, Bussadori G, Edmonson SE, Shah R, Arruda VR, Mingozzi F, Wright JF, et al (2011) Assessing the potential for AAV vector genotoxicity in a murine model. Blood 117: 3311-3319
-
(2011)
Blood
, vol.117
, pp. 3311-3319
-
-
Li, H.1
Malani, N.2
Hamilton, S.R.3
Schlachterman, A.4
Bussadori, G.5
Edmonson, S.E.6
Shah, R.7
Arruda, V.R.8
Mingozzi, F.9
Wright, J.F.10
-
10
-
-
55449122193
-
Telomerase reverse transcriptase delays aging in cancer-resistant mice
-
Tomas-Loba A, Flores I, Fernandez-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borras C, Matheu A, Klatt P, Flores JM, et al (2008) Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell 135: 609-622
-
(2008)
Cell
, vol.135
, pp. 609-622
-
-
Tomas-Loba, A.1
Flores, I.2
Fernandez-Marcos, P.J.3
Cayuela, M.L.4
Maraver, A.5
Tejera, A.6
Borras, C.7
Matheu, A.8
Klatt, P.9
Flores, J.M.10
-
11
-
-
79951795555
-
Healthy aging and disease: Role for telomere biology
-
Zhu H, Belcher M, van der Harst P (2011) Healthy aging and disease: Role for telomere biology? Clin Sci (Lond) 120: 427-440
-
(2011)
Clin Sci (Lond)
, vol.120
, pp. 427-440
-
-
Zhu, H.1
Belcher, M.2
van der Harst, P.3
|