Simultaneous quantification of centchroman and its 7-demethylated metabolite in rat dried blood spot samples using LC-MS/MS

Biomedical Chromatography

Volumn 26, Issue 9, 2012, Pages 1089-1095

  Lal, Jawahar ^a   Sharma, Nidhi ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

7 desmethyl centchroman; Centchroman; Dried blood spot; LC MS MS; Oral contraceptive; Pharmacokinetics

Indexed keywords

BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; SIGNAL TO NOISE RATIO; SOLVENT EXTRACTION;

7-DESMETHYL CENTCHROMAN; CENTCHROMAN; DRIED BLOOD SPOT; LC-MS-MS; LC.MS/MS; ORAL CONTRACEPTIVE; PLASMA SAMPLES; QUANTITATIVE DETERMINATIONS; SPOT SAMPLES;

METABOLITES;

7 DESMETHYL CENTCHROMAN; CARBAMAZEPINE; CENTCHROMAN; CHROMAN DERIVATIVE; DRUG METABOLITE; TRANS HYDROXY CHROMAN; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BLOOD VOLUME; CALIBRATION; DRIED BLOOD SPOT TESTING; DRUG BLOOD LEVEL; FEMALE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; METABOLITE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROOM TEMPERATURE; SIGNAL NOISE RATIO; SOLVENT EXTRACTION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84864803397     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1752     Document Type: Article

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