Knockdown of leptin A expression dramatically alters zebrafish development

General and Comparative Endocrinology

Volumn 178, Issue 3, 2012, Pages 562-572

  Liu, Qin ^a   Dalman, Mark ^a   Chen, Yun ^a   Akhter, Mashal ^a   Brahmandam, Sravya ^a   Patel, Yesha ^a   Lowe, Josef ^b   Thakkar, Mitesh ^b   Gregory, Akil Vuai ^a   Phelps, Daryllanae ^a   Riley, Caitlin ^a   Londraville, Richard L ^a  

^a UNIVERSITY OF AKRON   (United States)

^b NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

Author keywords

Auditory; Bone; Central nervous system; Differentiation; Metabolism; Visual

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LEPTIN; LEPTIN A; LEPTIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY SIZE; BRAIN CELL; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; EYE MALFORMATION; FETUS MALFORMATION; GENE SILENCING; HEART MUSCLE CELL; INNER EAR DEVELOPMENT; INNER EAR MALFORMATION; LARVAL DEVELOPMENT; NONHUMAN; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA CELL; WILD TYPE; ZEBRA FISH;

EID: 84864798718     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2012.07.011     Document Type: Article

References (60)

1. Ahima R.S. Adipose tissue as an endocrine organ. Obesity (Silver Spring) 2006, 14(Suppl 5):242S-249S.
2. Andermann P., Ungos J., Raible D.W. Neurogenin1 defines zebrafish cranial sensory ganglia precursors. Dev. Biol. 2002, 251:45-58.
3. Ando H., Kobayashi M., Tsubokawa T., Uyemura K., Furuta T., Okamoto H. Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Dev. Biol. 2005, 287:456-468.
4. Babb S.G., Kotradi S.M., Shah B., Chiappini-Williamson C., Bell L.N., Schmeiser G., Chen E., Liu Q., Marrs J.A. Zebrafish R-cadherin (Cdh4) controls visual system development and differentiation. Dev. Dyn. 2005, 233:930-945.
5. Bagatto B., Francl J., Liu B., Liu Q. Cadherin2 (N-cadherin) plays an essential role in zebrafish cardiovascular development. BMC Dev. Biol. 2006, 6:23.
6. Belgardt B.F., Brüning J.C. CNS leptin and insulin action in the control of energy homeostasis. Ann. N. Y. Acad. Sci. 2010, 1212:97-113.
7. Briscoe J., Pierani A., Jessell T.M., Ericson J. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 2000, 101:435-445.
8. Burrill J.D., Easter S.S. Development of the retinofugal projections in the embryonic and larval zebrafish (Brachydanio rerio). J. Comp. Neurol. 1994, 346:583-600.
9. Camand O., Turban S., Abitbol M., Guerre-Millo M. Embryonic expression of the leptin receptor gene in mesoderm-derived tissues. C R Biol. 2002, 325:77-87.
10. Ceccarini G., Flavell R.R., Butelman E.R., Synan M., Willnow T.E., Bar-Dagan M., Goldsmith S.J., Kreek M.J., Kothari P., Vallabhajosula S., Muir T.W., Friedman J.M. PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metab. 2009, 10:148-159.
11. Chen S.C., Cunningham J.J., Smeyne R.J. Expression of OB receptor splice variants during prenatal development of the mouse. J. Recept. Signal. Transduct. Res. 2000, 20:87-103.
12. Crespi E.J., Denver R.J. Leptin (ob gene) of the South African clawed frog Xenopus laevis. Proc. Natl. Acad. Sci. USA 2006, 103:10092-10097.
13. David L., Blum S., Feldman M.W., Lavi U., Hillel J. Recent duplication of the common carp (Cyprinus carpio L.) genome as revealed by analyses of microsatellite loci. Mol. Biol. Evol. 2003, 20:1425-1434.
14. Donato J., Cravo R.M., Frazão R., Elias C.F. Hypothalamic sites of leptin action linking metabolism and reproduction. Neuroendocrinology 2011, 93:9-18.
15. Driessler F., Baldock P.A. Hypothalamic regulation of bone. J. Mol. Endocrinol. 2010, 45:175-181.
16. Eisen J.S., Smith J.C. Controlling morpholino experiments: don't stop making antisense. Development 2008, 135:1735-1743.
17. Ekker S.C. Morphants: a new systematic vertebrate functional genomics approach. Yeast 2000, 17:302-306.
18. Frøiland E., Murashita K., Jørgensen E.H., Kurokawa T. Leptin and ghrelin in anadromous Arctic charr: cloning and change in expressions during a seasonal feeding cycle. Gen. Comp. Endocrinol. 2010, 165:136-143.
19. Gorissen M., Bernier N.J., Nabuurs S.B., Flik G., Huising M.O. Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution. J. Endocrinol. 2009, 201:329-339.
20. Haddon C., Lewis J. Early ear development in the embryo of the zebrafish Danio rerio. J. Comp. Neurol. 1996, 365:113-128.
21. Horner K.C., Troadec J.D., Blanchard M.P., Dallaporta M., Pio J. Receptors for leptin in the otic labyrinth and the cochlear-vestibular nerve of guinea pig are modified in hormone-induced anorexia. Heart Res. 2010, 270:48-55.
22. Huising M.O., Geven E.J., Kruiswijk C.P., Nabuurs S.B., Stolte E.H., Spanings F.A., Verburg-van Kemenade B.M., Flik G. Increased leptin expression in common carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation. Endocrinology 2006, 147:5786-5797.
23. Inoue T., Hojo M., Bessho Y., Tano Y., Lee J.E., Kageyama R. Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development 2002, 129:831-842.
24. Johnson R.M., Johnson T.M., Londraville R.L. Evidence for leptin expression in fishes. J. Exp. Zool. 2000, 286:718-724.
25. Karsenty G., Oury F. The central regulation of bone mass, the first link between bone remodeling and energy metabolism. J. Clin. Endocrinol. Metab. 2010, 95:4795-4801.
26. Knaut H., Blader P., Strähle U., Schier A.F. Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron 2005, 47:653-666.
27. Korzh V., Sleptsova I., Liao J., He J., Gong Z. Expression of zebrafish bHLH genes ngn1 and nrd defines distinct stages of neural differentiation. Dev. Dyn. 1998, 213:92-104.
28. Krauss S., Concordet J.P., Ingham P.W. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 1993, 75:1431-1444.
29. Krauss S., Johansen T., Korzh V., Fjose A. Expression pattern of zebrafish pax genes suggests a role in early brain regionalization. Nature 1991, 353:267-270.
30. Kurokawa T., Murashita K. Genomic characterization of multiple leptin genes and a leptin receptor gene in the Japanese medaka, Oryzias latipes. Gen. Comp. Endocrinol. 2009, 161:229-237.
31. Kurokawa T., Uji S., Suzuki T. Identification of cDNA coding for a homologue to mammalian leptin from pufferfish, Takifugu rubripes. Peptides 2005, 26:745-750.
32. Lee H.S., Kim K.R., Chung W.H., Cho Y.S., Hong S.H. Early sensorineural hearing loss in ob/ob mouse, an animal model of type 2 diabetes. Clin. Exp. Otorhinolaryngol. 2008, 1:211-216.
33. Liu B., Joel Duff R., Londraville R.L., Marrs J.A., Liu Q. Cloning and expression analysis of cadherin7 in the central nervous system of the embryonic zebrafish. Gene Expr. Patterns 2007, 7:15-22.
34. Liu Q., Babb S.G., Novince Z.M., Doedens A.L., Marrs J., Raymond P.A. Differential expression of cadherin-2 and cadherin-4 in the developing and adult zebrafish visual system. Vis. Neurosci. 2001, 18:923-933.
35. Liu Q., Chen Y., Copeland D., Ball H., Duff R.J., Rockich B., Londraville R.L. Expression of leptin receptor gene in developing and adult zebrafish. Gen. Comp. Endocrinol. 2010, 166:346-355.
36. Liu Q., Londraville R., Azodi E., Babb S., Chiappini C., Marrs J., Raymond P. Up-regulation of cadherin-2 and cadherin-4 in regenerating visual structures of adult zebrafish. Exp. Neurol. 2002, 177.
37. Liu Q., Sanborn K.L., Cobb N., Raymond P.A., Marrs J.A. R-cadherin expression in the developing and adult zebrafish visual system. J. Comp. Neurol. 1999, 410:303-319.
38. Londraville R., Niewiarowski P. Leptin signaling systems in reptiles and amphibians. Leptin in Non-mammalian Vertebrates 2011, Transworld Research Network, Kerala, India. M. Paolucci (Ed.).
39. Malicki J., Jo H., Pujic Z. Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning. Dev. Biol. 2003, 259:95-108.
40. Masai I., Lele Z., Yamaguchi M., Komori A., Nakata A., Nishiwaki Y., Wada H., Tanaka H., Nojima Y., Hammerschmidt M., Wilson S.W., Okamoto H. N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development 2003, 130:2479-2494.
41. Moen A.G., Murashita K., Finn R.N. Ontogeny of energy homeostatic pathways via neuroendocrine signaling in Atlantic salmon. Dev. Neurobiol. 2010, 70:649-658.
42. Morrow E.M., Furukawa T., Lee J.E., Cepko C.L. NeuroD regulates multiple functions in the developing neural retina in rodent. Development 1999, 126:23-36.
43. Nasevicius A., Ekker S.C. Effective targeted gene 'knockdown' in zebrafish. Nat. Genet. 2000, 26:216-220.
44. Odenthal J., Haffter P., Vogelsang E., Brand M., van Eeden F.J., Furutani-Seiki M., Granato M., Hammerschmidt M., Heisenberg C.P., Jiang Y.J., Kane D.A., Kelsh R.N., Mullins M.C., Warga R.M., Allende M.L., Weinberg E.S., Nusslein-Volhard C. Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development 1996, 123:103-115.
45. Oxtoby E., Jowett T. Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development. Nucleic Acids Res. 1993, 21:1087-1095.
46. Parsons M.J., Pollard S.M., Saude L., Feldman B., Coutinho P., Hirst E.M., Stemple D.L. Zebrafish mutants identify an essential role for laminins in notochord formation. Development 2002, 129:3137-3146.
47. Pénicaud L. The neural feedback loop between the brain and adipose tissues. Endocr. Dev. 2010, 19:84-92.
48. Pfundt B., Sauerwein H., Mielenz M. Leptin mRNA and protein immunoreactivity in adipose tissue and liver of rainbow trout (Oncorhynchus mykiss) and immunohistochemical localization in liver. Anat. Histol. Embryol. 2009, 38:406-410.
49. Roa J., Tena-Sempere M. Energy balance and puberty onset: emerging role of central mTOR signaling. Trends Endocrinol. Metab. 2010, 21:519-528.
50. Rønnestad I., Nilsen T.O., Murashita K., Angotzi A.R., Gamst A.G., Moen S.O., Stefansson P., Kling B., Björnsson T., Kurokawa T. Leptin and leptin receptor genes in Atlantic salmon: cloning, phylogeny, tissue distribution and expression correlated to long-term feeding status. Gen. Comp. Endocrinol. 2010, 168:55-70.
51. Sheffield V.C. The blind leading the obese: the molecular pathophysiology of a human obesity syndrome. Trans. Am. Clin. Climatol. Assoc. 2010, 121:172-182.
52. Sheridan M.A. Lipid dynamics in fish: aspects of absorption, transportation, deposition, and mobilization. Comp. Biochem. Physiol. 1988, 90B:679-690.
53. Stuermer C.A. Retinotopic organization of the developing retinotectal projection in the zebrafish embryo. J. Neurosci. 1988, 8:4513-4530.
54. Talbot W.S., Trevarrow B., Halpern M.E., Melby A.E., Farr G., Postlethwait J.H., Jowett T., Kimmel C.B., Kimelman D. A homeobox gene essential for zebrafish notochord development. Nature 1995, 378:150-157.
55. Tang R., Dodd A., Lai D., McNabb W.C., Love D.R. Validation of zebrafish (Danio rerio) reference genes for quantitative real-time RT-PCR normalization. Acta Biochim. Biophys. Sin. (Shanghai) 2007, 39:384-390.
56. Westerfield M. The Zebrafish Book A guide for the Laboratory Use of Zebrafish (Danio rerio) 2007, Univ. of Oregon Press, Eugene, OR. fifth ed.
57. Yan R.T., Ma W., Liang L., Wang S.Z. BHLH genes and retinal cell fate specification. Mol. Neurobiol. 2005, 32:157-171.
58. Yelon D. Cardiac patterning and morphogenesis in zebrafish. Dev. Dyn. 2001, 222:552-563.
59. Yelon D., Stainier D.Y. Patterning during organogenesis: genetic analysis of cardiac chamber formation. Semin. Cell Dev. Biol. 1999, 10:93-98.
60. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and it human homologue. Nature 1994, 372:425-431.