CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates

European Journal of Immunology

Volumn 42, Issue 8, 2012, Pages 2019-2030

  Romain, Gabrielle ^a,b   van Gulck, Ellen ^c   Epaulard, Olivier ^a,b   Oh, Sangkon ^d,e   Li, Dapeng ^d,e   Zurawski, Gerard ^d,e   Zurawski, Sandra ^d,e   Cosma, Antonio ^a,b   Adam, Lucille ^a,b   Chapon, Catherine ^a,b   Todorova, Biliana ^a,b   Banchereau, Jacques ^d,e   Dereuddre Bosquet, Nathalie ^a,b   Vanham, Guido ^c,f   Le Grand, Roger ^a,b   Martinon, Frédéric ^a,b,e  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^d BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^e INSERM   (France)

^f VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Antigen presenting cells; Dendritic cells; Immune responses; Vaccination

Indexed keywords

CD34 ANTIGEN; DENDRITIC CELL VACCINE; GAG PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 2; LANGERIN; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PATTERN RECOGNITION RECEPTOR; T6 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BONE MARROW; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; DENDRITIC CELL; EX VIVO STUDY; IMMUNOGENICITY; LANGERHANS CELL; MACROPHAGE; MONOCYTE; MYELOID DENDRITIC CELL; NONHUMAN; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, CD1; ANTIGENS, CD11C; ANTIGENS, CD34; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DENDRITIC CELLS; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; INTERFERON-GAMMA; INTERLEUKIN-2; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MACACA FASCICULARIS; MACROPHAGES; MALE; MANNOSE-BINDING LECTINS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864779841     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242478     Document Type: Article

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