메뉴 건너뛰기




Volumn 2, Issue 4, 2010, Pages 467-476

Arcelis™ AGS-004 dendritic cell-based immunotherapy for HIV infection

Author keywords

CD40 ligand; dendritic cell; HIV; therapeutic vaccine

Indexed keywords

AGS 004; ANTIRETROVIRUS AGENT; ARCELIS; B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; INTERFERON; INTERLEUKIN 12; RNA; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 77954973455     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.10.28     Document Type: Review
Times cited : (17)

References (73)
  • 1
    • 61949441350 scopus 로고    scopus 로고
    • Diabetes mellitus, preexisting coronary heart disease, and the risk of subsequent coronary heart disease events in patients infected with human immunodeficiency virus: The data collection on adverse events of anti-HIV drugs (d:A:D study)
    • Worm SW, De Wit S, Weber R et al.: Diabetes mellitus, preexisting coronary heart disease, and the risk of subsequent coronary heart disease events in patients infected with human immunodeficiency virus: the data collection on adverse events of anti-HIV drugs (d:A:D study). Circulation 119(6), 805-811 (2009).
    • (2009) Circulation , vol.119 , Issue.6 , pp. 805-811
    • Worm, S.W.1    De Wit, S.2    Weber, R.3
  • 2
    • 34248590939 scopus 로고    scopus 로고
    • Chronic renal failure among HIV-1-infected patients
    • Mocroft A, Kirk O, Gatell J et al.: Chronic renal failure among HIV-1-infected patients. AIDS 21(9), 1119-1127 (2007).
    • (2007) AIDS , vol.21 , Issue.9 , pp. 1119-1127
    • Mocroft, A.1    Kirk, O.2    Gatell, J.3
  • 3
    • 65449153627 scopus 로고    scopus 로고
    • The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time
    • Lima VD, Harrigan R, Bangsberg DR et al.: The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. J. Acquir. Immune Defic. Syndr. 50(5), 529-536 (2009).
    • (2009) J. Acquir. Immune Defic. Syndr. , vol.50 , Issue.5 , pp. 529-536
    • Lima, V.D.1    Harrigan, R.2    Bangsberg, D.R.3
  • 4
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • Steigbigel RT, Cooper DA, Kumar PN et al.: Raltegravir with optimized background therapy for resistant HIV-1 infection. N. Engl. J. Med. 359(4), 339-354 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.4 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3
  • 5
    • 0037043652 scopus 로고    scopus 로고
    • Antiretroviral-drug resistance among patients recently infected with HIV
    • Little SJ, Holte S, Routy JP et al.: Antiretroviral-drug resistance among patients recently infected with HIV. N. Engl. J. Med. 347(6), 385-394 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , Issue.6 , pp. 385-394
    • Little, S.J.1    Holte, S.2    Routy, J.P.3
  • 6
    • 73349134686 scopus 로고    scopus 로고
    • Abacavir-lamivudine versus tenofovir- emtricitabine for initial HIV-1 therapy
    • Sax PE, Tierney C, Collier AC et al.: Abacavir-lamivudine versus tenofovir- emtricitabine for initial HIV-1 therapy. N. Engl. J. Med. 361(23), 2230-2240 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , Issue.23 , pp. 2230-2240
    • Sax, P.E.1    Tierney, C.2    Collier, A.C.3
  • 7
    • 16544393196 scopus 로고    scopus 로고
    • Role of therapeutic vaccines in the control of HIV-1
    • Kinloch-de Loes S: Role of therapeutic vaccines in the control of HIV-1. J. Antimicrob. Chemother. 53(4), 562-566 (2004).
    • (2004) J. Antimicrob. Chemother. , vol.53 , Issue.4 , pp. 562-566
    • Kinloch-De Loes, S.1
  • 8
    • 50449090525 scopus 로고    scopus 로고
    • An HIV vaccine - Challenges and prospects
    • Johnston MI, Fauci AS: An HIV vaccine - challenges and prospects. N. Engl. J. Med. 359(9), 888-890 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.9 , pp. 888-890
    • Johnston, M.I.1    Fauci, A.S.2
  • 9
    • 68349157582 scopus 로고    scopus 로고
    • Toward an AIDS vaccine: Lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts
    • Sodora DL, Allan JS, Apetrei C et al.: Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat. Med. 15(8), 861-865 (2009).
    • (2009) Nat. Med. , vol.15 , Issue.8 , pp. 861-865
    • Sodora, D.L.1    Allan, J.S.2    Apetrei, C.3
  • 10
    • 0030726383 scopus 로고    scopus 로고
    • Host factors in the pathogenesis of HIV disease
    • Cohen OJ, Kinter A, Fauci AS: Host factors in the pathogenesis of HIV disease. Immunol. Rev. 159, 31-48 (1997).
    • (1997) Immunol. Rev. , vol.159 , pp. 31-48
    • Cohen, O.J.1    Kinter, A.2    Fauci, A.S.3
  • 11
    • 44949154503 scopus 로고    scopus 로고
    • + T cell efficacy in vaccination and disease
    • + T cell efficacy in vaccination and disease. Nat. Med. 14(6), 623-628 (2008).
    • (2008) Nat. Med. , vol.14 , Issue.6 , pp. 623-628
    • Appay, V.1    Douek, D.C.2    Price, D.A.3
  • 12
    • 63449124466 scopus 로고    scopus 로고
    • Emerging concepts in the immunopathogenesis of AIDS
    • Douek DC, Roederer M, Koup RA: Emerging concepts in the immunopathogenesis of AIDS. Annu. Rev. Med. 60, 471-484 (2009).
    • (2009) Annu. Rev. Med. , vol.60 , pp. 471-484
    • Douek, D.C.1    Roederer, M.2    Koup, R.A.3
  • 14
    • 63749103545 scopus 로고    scopus 로고
    • HIV GAG p24 specific responses secreting IFN-γ and/or IL-2 in treatment-naive individuals in acute infection early disease (AIED) are associated with low viral load
    • Ndongala Ml, Peretz Y, Boulet S et al.: HIV GAG p24 specific responses secreting IFN-γ and/or IL-2 in treatment-naive individuals in acute infection early disease (AIED) are associated with low viral load. Clin. Immunol. 131(2), 277-287 (2009).
    • (2009) Clin. Immunol. , vol.131 , Issue.2 , pp. 277-287
    • Ml, N.1    Peretz, Y.2    Boulet, S.3
  • 15
    • 34249852256 scopus 로고    scopus 로고
    • HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
    • Saez-Cirion A, Lacabaratz C, Lambotte O et al.: HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc. Natl Acad. Sci. USA 104(16), 6776-6781 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.16 , pp. 6776-6781
    • Saez-Cirion, A.1    Lacabaratz, C.2    Lambotte, O.3
  • 16
    • 40049094957 scopus 로고    scopus 로고
    • Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy
    • Pereyra F, Addo MM, Kaufmann DE et al.: Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J. Infect. Dis. 197(4), 563-571 (2008).
    • (2008) J. Infect. Dis. , vol.197 , Issue.4 , pp. 563-571
    • Pereyra, F.1    Addo, M.M.2    Kaufmann, D.E.3
  • 17
    • 34447322319 scopus 로고    scopus 로고
    • + T cell subsets expressing CD8aaand IL-7Rain viremic, aviremic and slow progressor HIV-1-infected subjects
    • + T cell subsets expressing CD8aaand IL-7Rain viremic, aviremic and slow progressor HIV-1-infected subjects. Clin. Immunol. 124(2), 149-157 (2007).
    • (2007) Clin. Immunol. , vol.124 , Issue.2 , pp. 149-157
    • Boulassel, M.R.1    Mercier, F.2    Gilmore, N.3    Routy, J.P.4
  • 18
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y et al.: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68(7), 4650-4655 (1994).
    • (1994) J. Virol. , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3
  • 19
    • 0033559648 scopus 로고    scopus 로고
    • + T cell depletion in simian immunodeficiency virus-infected macaques
    • + T cell depletion in simian immunodeficiency virus-infected macaques. J. Exp. Med. 189(6), 991-998 (1999).
    • (1999) J. Exp. Med. , vol.189 , Issue.6 , pp. 991-998
    • Jin, X.1    Bauer, D.E.2    Tuttleton, S.E.3
  • 20
    • 0034699512 scopus 로고    scopus 로고
    • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
    • Allen TM, Oconnor DH, Jing P et al.: Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 407(6802), 386-390 (2000).
    • (2000) Nature , vol.407 , Issue.6802 , pp. 386-390
    • Allen, T.M.1    Oconnor, D.H.2    Jing, P.3
  • 21
    • 27144513224 scopus 로고    scopus 로고
    • + T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution
    • + T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution. J. Virol. 79(21), 13239-13249 (2005).
    • (2005) J. Virol. , vol.79 , Issue.21 , pp. 13239-13249
    • Allen, T.M.1    Altfeld, M.2    Geer, S.C.3
  • 22
    • 33749009709 scopus 로고    scopus 로고
    • + T cells leads to reversible immune dysfunction
    • + T cells leads to reversible immune dysfunction. Nat. Med. 12(10), 1198-1202 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.10 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3
  • 24
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW et al.: Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12(12), 1365-1371 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3
  • 25
    • 65649102237 scopus 로고    scopus 로고
    • Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection
    • Jiang W, Lederman MM, Hunt P et al.: Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J. Infect. Dis. 199(8), 1177-1185 (2009).
    • (2009) J. Infect. Dis. , vol.199 , Issue.8 , pp. 1177-1185
    • Jiang, W.1    Lederman, M.M.2    Hunt, P.3
  • 26
    • 77952507646 scopus 로고    scopus 로고
    • Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease
    • Naeger DM, Martin JN, Sinclair E et al.: Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. PLoS One 5(1), E8886 (2010).
    • (2010) PLoS One , vol.5 , Issue.1
    • Naeger, D.M.1    Martin, J.N.2    Sinclair, E.3
  • 27
    • 75349114036 scopus 로고    scopus 로고
    • Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy
    • Deeks SG: Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy. Top. HIV Med. 17(4), 118-123 (2009).
    • (2009) Top. HIV Med. , vol.17 , Issue.4 , pp. 118-123
    • Deeks, S.G.1
  • 28
    • 33847301982 scopus 로고    scopus 로고
    • +CD25- T cells into islet-protective Foxp3+ regulatory T cells
    • +CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc. Natl Acad. Sci. USA 104(8), 2821-2826 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.8 , pp. 2821-2826
    • Luo, X.1    Tarbell, K.V.2    Yang, H.3
  • 29
    • 0037128167 scopus 로고    scopus 로고
    • Interferon aband interleukin 12 responses to viral infections: Pathways regulating dendritic cell cytokine expression in vivo
    • Dalod M, Salazar-Mather TP, Malmgaard L et al.: Interferon aband interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J. Exp. Med. 195(4), 517-528 (2002).
    • (2002) J. Exp. Med. , vol.195 , Issue.4 , pp. 517-528
    • Dalod, M.1    Salazar-Mather, T.P.2    Malmgaard, L.3
  • 30
    • 3042545974 scopus 로고    scopus 로고
    • The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation
    • Fujii S, Liu K, Smith C, Bonito AJ, Steinman RM: The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J. Exp. Med. 199(12), 1607-1618 (2004).
    • (2004) J. Exp. Med. , vol.199 , Issue.12 , pp. 1607-1618
    • Fujii, S.1    Liu, K.2    Smith, C.3    Bonito, A.J.4    Steinman, R.M.5
  • 31
    • 67649253072 scopus 로고    scopus 로고
    • HIV interactions with monocytes and dendritic cells: Viral latency and reservoirs
    • Coleman CM, Wu L: HIV interactions with monocytes and dendritic cells: viral latency and reservoirs. Retrovirology 6, 51 (2009).
    • (2009) Retrovirology , vol.6 , pp. 51
    • Coleman, C.M.1    Wu, L.2
  • 32
    • 0032896741 scopus 로고    scopus 로고
    • T cell-tropic simian immunodeficiency virus (SIV) and simian-human immunodeficiency viruses are readily transmitted by vaginal inoculation of rhesus macaques, and langerhans cells of the female genital tract are infected with SIV
    • Miller CJ, Hu J: T cell-tropic simian immunodeficiency virus (SIV) and simian-human immunodeficiency viruses are readily transmitted by vaginal inoculation of rhesus macaques, and langerhans cells of the female genital tract are infected with SIV. J. Infect. Dis. 179(Suppl. 3), S413-S417 (1999).
    • (1999) J. Infect. Dis. , vol.179 , Issue.SUPPL. 3
    • Miller, C.J.1    Hu, J.2
  • 33
    • 51649113484 scopus 로고    scopus 로고
    • The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways
    • Lambert AA, Gilbert C, Richard M, Beaulieu AD, Tremblay MJ: The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways. Blood 112(4), 1299-1307 (2008).
    • (2008) Blood , vol.112 , Issue.4 , pp. 1299-1307
    • Lambert, A.A.1    Gilbert, C.2    Richard, M.3    Beaulieu, A.D.4    Tremblay, M.J.5
  • 34
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J: Taking dendritic cells into medicine. Nature 449(7161), 419-426 (2007).
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 35
    • 0033514364 scopus 로고    scopus 로고
    • Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
    • Pulendran B, Smith JL, Caspary G et al.: Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc. Natl Acad. Sci. USA 96(3), 1036-1041 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , Issue.3 , pp. 1036-1041
    • Pulendran, B.1    Smith, J.L.2    Caspary, G.3
  • 36
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 392(6673), 245-252 (1998).
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 37
    • 51349141264 scopus 로고    scopus 로고
    • Dendritic cells in vivo: A key target for a new vaccine science
    • Steinman RM: Dendritic cells in vivo: a key target for a new vaccine science. Immunity 29(3), 319-324 (2008).
    • (2008) Immunity , vol.29 , Issue.3 , pp. 319-324
    • Steinman, R.M.1
  • 39
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A: Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6(8), 769-776 (2005).
    • (2005) Nat. Immunol. , vol.6 , Issue.8 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 41
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • Randolph GJ, Angeli V, Swartz MA: Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat. Rev. Immunol. 5(8), 617-628 (2005).
    • (2005) Nat. Rev. Immunol. , vol.5 , Issue.8 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 42
    • 33845898737 scopus 로고    scopus 로고
    • Steady-state and inflammatory dendritic-cell development
    • Shortman K, Naik SH: Steady-state and inflammatory dendritic-cell development. Nat. Rev. Immunol. 7(1), 19-30 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , Issue.1 , pp. 19-30
    • Shortman, K.1    Naik, S.H.2
  • 43
    • 17444371691 scopus 로고    scopus 로고
    • Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes
    • Nobile C, Petit C, Moris A et al.: Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes. J. Virol. 79(9), 5386-5399 (2005).
    • (2005) J. Virol. , vol.79 , Issue.9 , pp. 5386-5399
    • Nobile, C.1    Petit, C.2    Moris, A.3
  • 44
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
    • Tacken PJ, De Vries IJ, Torensma R, Figdor CG: Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat. Rev. Immunol. 7(10), 790-802 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , Issue.10 , pp. 790-802
    • Tacken, P.J.1    De Vries, I.J.2    Torensma, R.3    Figdor, C.G.4
  • 45
    • 13844275371 scopus 로고    scopus 로고
    • HIV-1 VPR inhibits the maturation and activation of macrophages and dendritic cells in vitro
    • Muthumani K, Hwang DS, Choo AY et al.: HIV-1 VPR inhibits the maturation and activation of macrophages and dendritic cells in vitro. Int. Immunol. 17(2), 103-116 (2005).
    • (2005) Int. Immunol. , vol.17 , Issue.2 , pp. 103-116
    • Muthumani, K.1    Hwang, D.S.2    Choo, A.Y.3
  • 47
    • 65549123647 scopus 로고    scopus 로고
    • HIV infection affects blood myeloid dendritic cells after successful therapy and despite nonprogressing clinical disease
    • Fontaine J, Coutlee F, Tremblay C, Routy JP, Poudrier J, Roger M: HIV infection affects blood myeloid dendritic cells after successful therapy and despite nonprogressing clinical disease. J. Infect. Dis. 199(7), 1007-1018 (2009).
    • (2009) J. Infect. Dis. , vol.199 , Issue.7 , pp. 1007-1018
    • Fontaine, J.1    Coutlee, F.2    Tremblay, C.3    Routy, J.P.4    Poudrier, J.5    Roger, M.6
  • 48
    • 67649222245 scopus 로고    scopus 로고
    • The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, r90
    • Tcherepanova I, Starr A, Lackford B et al.: The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, r90. PLoS One 4(6), E5853 (2009).
    • (2009) PLoS One , vol.4 , Issue.6
    • Tcherepanova, I.1    Starr, A.2    Lackford, B.3
  • 49
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen SG, Vieville C, Whizin N et al.: Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat. Med. 15(3), 293-299 (2009).
    • (2009) Nat. Med. , vol.15 , Issue.3 , pp. 293-299
    • Hansen, S.G.1    Vieville, C.2    Whizin, N.3
  • 51
    • 1642500367 scopus 로고    scopus 로고
    • Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: Changes after antiretroviral therapy
    • Harari A, Petitpierre S, Vallelian F, Pantaleo G: Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy. Blood 103(3), 966-972 (2004).
    • (2004) Blood , vol.103 , Issue.3 , pp. 966-972
    • Harari, A.1    Petitpierre, S.2    Vallelian, F.3    Pantaleo, G.4
  • 52
    • 3042807072 scopus 로고    scopus 로고
    • Therapeutic vaccines for chronic infections
    • Autran B, Carcelain G, Combadiere B, Debre P: Therapeutic vaccines for chronic infections. Science 305(5681), 205-208 (2004).
    • (2004) Science , vol.305 , Issue.5681 , pp. 205-208
    • Autran, B.1    Carcelain, G.2    Combadiere, B.3    Debre, P.4
  • 53
    • 0035417932 scopus 로고    scopus 로고
    • + progenitor-derived dendritic cell vaccine
    • Banchereau J, Palucka AK, Dhodapkar M et al.: Immune and clinical responses in patients with metastatic melanoma to CD34+ progenitor-derived dendritic cell vaccine. Cancer Res. 61(17), 6451-6458 (2001).
    • (2001) Cancer Res. , vol.61 , Issue.17 , pp. 6451-6458
    • Banchereau, J.1    Palucka, A.K.2    Dhodapkar, M.3
  • 54
    • 0037943937 scopus 로고    scopus 로고
    • Durable complete clinical responses in a Phase I/II trial using an autologous melanoma cell/dendritic cell vaccine
    • ORourke MG, Johnson M, Lanagan C et al.: Durable complete clinical responses in a Phase I/II trial using an autologous melanoma cell/dendritic cell vaccine. Cancer Immunol. Immunother. 52(6), 387-395 (2003).
    • (2003) Cancer Immunol. Immunother. , vol.52 , Issue.6 , pp. 387-395
    • Orourke, M.G.1    Johnson, M.2    Lanagan, C.3
  • 56
    • 0037234103 scopus 로고    scopus 로고
    • Therapeutic dendritic-cell vaccine for simian AIDS
    • Lu W, Wu X, Lu Y, Guo W, Andrieu JM: Therapeutic dendritic-cell vaccine for simian AIDS. Nat. Med. 9(1), 27-32 (2003).
    • (2003) Nat. Med. , vol.9 , Issue.1 , pp. 27-32
    • Lu, W.1    Wu, X.2    Lu, Y.3    Guo, W.4    Andrieu, J.M.5
  • 57
    • 0032080810 scopus 로고    scopus 로고
    • A pilot clinical trial of HIV antigen-pulsed allogeneic and autologous dendritic cell therapy in HIV-infected patients
    • Kundu SK, Engleman E, Benike C et al.: A pilot clinical trial of HIV antigen-pulsed allogeneic and autologous dendritic cell therapy in HIV-infected patients. AIDS Res. Hum. Retroviruses 14(7), 551-560 (1998).
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , Issue.7 , pp. 551-560
    • Kundu, S.K.1    Engleman, E.2    Benike, C.3
  • 58
    • 11144283687 scopus 로고    scopus 로고
    • Therapeutic dendritic-cell vaccine for chronic HIV-1 infection
    • Lu W, Arraes LC, Ferreira WT, Andrieu JM: Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. Nat. Med. 10(12), 1359-1365 (2004).
    • (2004) Nat. Med. , vol.10 , Issue.12 , pp. 1359-1365
    • Lu, W.1    Arraes, L.C.2    Ferreira, W.T.3    Andrieu, J.M.4
  • 59
    • 20844456226 scopus 로고    scopus 로고
    • Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection
    • Garcia F, Lejeune M, Climent N et al.: Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection. J. Infect. Dis. 191(10), 1680-1685 (2005).
    • (2005) J. Infect. Dis. , vol.191 , Issue.10 , pp. 1680-1685
    • Garcia, F.1    Lejeune, M.2    Climent, N.3
  • 60
    • 33646480371 scopus 로고    scopus 로고
    • Peptide-loaded dendritic-cell vaccination followed by treatment interruption for chronic HIV-1 infection: A Phase i trial
    • Ide F, Nakamura T, Tomizawa M et al.: Peptide-loaded dendritic-cell vaccination followed by treatment interruption for chronic HIV-1 infection: a Phase I trial. J. Med. Virol. 78(6), 711-718 (2006).
    • (2006) J. Med. Virol. , vol.78 , Issue.6 , pp. 711-718
    • Ide, F.1    Nakamura, T.2    Tomizawa, M.3
  • 61
    • 40449119721 scopus 로고    scopus 로고
    • Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals
    • Connolly NC, Whiteside TL, Wilson C, Kondragunta V, Rinaldo CR, Riddler SA: Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals. Clin. Vaccine Immunol. 15(2), 284-292 (2008).
    • (2008) Clin. Vaccine Immunol. , vol.15 , Issue.2 , pp. 284-292
    • Connolly, N.C.1    Whiteside, T.L.2    Wilson, C.3    Kondragunta, V.4    Rinaldo, C.R.5    Riddler, S.A.6
  • 62
    • 70349299844 scopus 로고    scopus 로고
    • A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy
    • Gandhi RT, ONeill D, Bosch RJ et al.: A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy. Vaccine 27(43), 6088-6094 (2009).
    • (2009) Vaccine , vol.27 , Issue.43 , pp. 6088-6094
    • Gandhi, R.T.1    Oneill, D.2    Bosch, R.J.3
  • 63
    • 0036839319 scopus 로고    scopus 로고
    • Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells
    • Marovich MA, Mascola JR, Eller MA et al.: Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells. J. Infect. Dis. 186(9), 1242-1252 (2002).
    • (2002) J. Infect. Dis. , vol.186 , Issue.9 , pp. 1242-1252
    • Marovich, M.A.1    Mascola, J.R.2    Eller, M.A.3
  • 64
    • 68449088239 scopus 로고    scopus 로고
    • + T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes
    • + T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes. AIDS 23(11), 1329-1340 (2009).
    • (2009) AIDS , vol.23 , Issue.11 , pp. 1329-1340
    • Kloverpris, H.1    Karlsson, I.2    Bonde, J.3
  • 65
    • 0036729032 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection
    • Addo MM, Yu XG, Rosenberg ES, Walker BD, Altfeld M: Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection. DNA Cell Biol. 21(9), 671-678 (2002).
    • (2002) DNA Cell Biol. , vol.21 , Issue.9 , pp. 671-678
    • Addo, M.M.1    Yu, X.G.2    Rosenberg, E.S.3    Walker, B.D.4    Altfeld, M.5
  • 66
    • 0035451404 scopus 로고    scopus 로고
    • Vpr is preferentially targeted by CTL during HIV-1 infection
    • Altfeld M, Addo MM, Eldridge RL et al.: Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol. 167(5), 2743-2752 (2001).
    • (2001) J. Immunol. , vol.167 , Issue.5 , pp. 2743-2752
    • Altfeld, M.1    Addo, M.M.2    Eldridge, R.L.3
  • 67
    • 33845624525 scopus 로고    scopus 로고
    • The immunoregulatory effects of HIV-1 Nef on dendritic cells and the pathogenesis of aids
    • Quaranta MG, Mattioli B, Giordani L, Viora M: The immunoregulatory effects of HIV-1 Nef on dendritic cells and the pathogenesis of aids. FASEB J. 20(13), 2198-2208 (2006).
    • (2006) FASEB J. , vol.20 , Issue.13 , pp. 2198-2208
    • Quaranta, M.G.1    Mattioli, B.2    Giordani, L.3    Viora, M.4
  • 68
    • 45149125905 scopus 로고    scopus 로고
    • Multiplex RT-PCR amplification of HIV genes to create a completely autologous DC-based immunotherapy for the treatment of HIV infection
    • Tcherepanova I, Harris J, Starr A et al.: Multiplex RT-PCR amplification of HIV genes to create a completely autologous DC-based immunotherapy for the treatment of HIV infection. PLoS One 3(1), E1489 (2008).
    • (2008) PLoS One , vol.3 , Issue.1
    • Tcherepanova, I.1    Harris, J.2    Starr, A.3
  • 69
    • 34748892996 scopus 로고    scopus 로고
    • Dendritic cells for active immunotherapy: Optimizing design and manufacture in order to develop commercially and clinically viable products
    • Nicolette CA, Healey D, Tcherepanova I et al.: Dendritic cells for active immunotherapy: optimizing design and manufacture in order to develop commercially and clinically viable products. Vaccine 25(Suppl. 2), B47-B60 (2007).
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Nicolette, C.A.1    Healey, D.2    Tcherepanova, I.3
  • 70
    • 54049140895 scopus 로고    scopus 로고
    • Priming of a novel subset of CD28+ rapidly expanding high-avidity effector memory CTL by post maturation electroporation-CD40L dendritic cells is IL-12 dependent
    • Debenedette MA, Calderhead DM, Ketteringham H et al.: Priming of a novel subset of CD28+ rapidly expanding high-avidity effector memory CTL by post maturation electroporation-CD40L dendritic cells is IL-12 dependent. J. Immunol. 181(8), 5296-5305 (2008).
    • (2008) J. Immunol. , vol.181 , Issue.8 , pp. 5296-5305
    • Debenedette, M.A.1    Calderhead, D.M.2    Ketteringham, H.3
  • 71
    • 73549125003 scopus 로고    scopus 로고
    • Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy
    • Routy JP, Boulassel MR, Yassine-Diab B et al.: Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy. Clin. Immunol. 134(2), 140-147 (2010).
    • (2010) Clin. Immunol. , vol.134 , Issue.2 , pp. 140-147
    • Routy, J.P.1    Boulassel, M.R.2    Yassine-Diab, B.3
  • 72
    • 33748078472 scopus 로고    scopus 로고
    • Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: The results of AIDS Clinical Trials Group 5068
    • Jacobson JM, Pat Bucy R, Spritzler J et al.: Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068. J. Infect. Dis. 194(5), 623-632 (2006).
    • (2006) J. Infect. Dis. , vol.194 , Issue.5 , pp. 623-632
    • Jacobson, J.M.1    Pat Bucy, R.2    Spritzler, J.3
  • 73
    • 77954965144 scopus 로고    scopus 로고
    • Participants perceptions and representations after dendritic cell immunotherapy and HAART discontinuation in the CTN 239 study
    • Lebouche B, Tremblay P, Quesnel M et al.: Participants perceptions and representations after dendritic cell immunotherapy and HAART discontinuation in the CTN 239 study. Can. J. Infect. Dis. Med. Microbiol. 21(Suppl. B), 73 (2010).
    • (2010) Can. J. Infect. Dis. Med. Microbiol. , vol.21 , Issue.SUPPL. B , pp. 73
    • Lebouche, B.1    Tremblay, P.2    Quesnel, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.