메뉴 건너뛰기




Volumn 303, Issue 3, 2012, Pages

Hyperhomocysteinemia decreases intestinal motility leading to constipation

Author keywords

Intestinal remodeling; Matrix metalloproteinase 9

Indexed keywords

CYSTATHIONINE BETA SYNTHASE; GELATINASE B; HOMOCYSTEINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

EID: 84864769389     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00423.2011     Document Type: Article
Times cited : (26)

References (44)
  • 1
    • 84864767803 scopus 로고    scopus 로고
    • A protocol for in vivo detection of reactive oxygen species
    • doi:10.1038/nprot.2008.23
    • Owusu-Ansah E, Yavari A, Banerjee U. A protocol for in vivo detection of reactive oxygen species. Protocol Exchange 2008. doi:10.1038/nprot.2008.23.
    • (2008) Protocol Exchange
    • Owusu-Ansah, E.1    Yavari, A.2    Banerjee, U.3
  • 5
    • 58949100279 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease: Effect on matrix metalloproteinases
    • Claramunt RM, Bouissane L, Cabildo MP, Cornago MP, Elguero J, Radziwon A, Medina C. Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease: effect on matrix metalloproteinases. Bioorg Med Chem 17: 1290-1296, 2009.
    • (2009) Bioorg Med Chem , vol.17 , pp. 1290-1296
    • Claramunt, R.M.1    Bouissane, L.2    Cabildo, M.P.3    Cornago, M.P.4    Elguero, J.5    Radziwon, A.6    Medina, C.7
  • 10
    • 42449117676 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: Correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications
    • Erzin Y, Uzun H, Celik AF, Aydin S, Dirican A, Uzunismail H. Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications. J Clin Gastroenterol 42: 481-486, 2008.
    • (2008) J Clin Gastroenterol , vol.42 , pp. 481-486
    • Erzin, Y.1    Uzun, H.2    Celik, A.F.3    Aydin, S.4    Dirican, A.5    Uzunismail, H.6
  • 12
    • 78651230951 scopus 로고    scopus 로고
    • X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/+, hyperhomocysteinemic (CBS-/+) and diabetic (Ins2-/+) mice
    • Givvimani S, Sen U, Tyagi N, Munjal C, Tyagi SC. X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/+, hyperhomocysteinemic (CBS-/+) and diabetic (Ins2-/+) mice. Arch Physiol Biochem 117: 1-7, 2011.
    • (2011) Arch Physiol Biochem , vol.117 , pp. 1-7
    • Givvimani, S.1    Sen, U.2    Tyagi, N.3    Munjal, C.4    Tyagi, S.C.5
  • 13
    • 0035068548 scopus 로고    scopus 로고
    • Homocysteineassociated acute mesenteric artery occlusion treated with thrombectomy and bowel resection
    • Gradman WS, Daniel J, Miller B, Haji-Aghaii M. Homocysteineassociated acute mesenteric artery occlusion treated with thrombectomy and bowel resection. Ann Vasc Surg 15: 247-250, 2001.
    • (2001) Ann Vasc Surg , vol.15 , pp. 247-250
    • Gradman, W.S.1    Daniel, J.2    Miller, B.3    Haji-Aghaii, M.4
  • 16
    • 54049156457 scopus 로고    scopus 로고
    • Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype
    • Hotoleanu C, Andercou O, Andercou A. Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype. Vasc Endovascular Surg 42: 477-481, 2008.
    • (2008) Vasc Endovascular Surg , vol.42 , pp. 477-481
    • Hotoleanu, C.1    Andercou, O.2    Andercou, A.3
  • 17
    • 78651345743 scopus 로고    scopus 로고
    • Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney
    • Hwang SY, Siow YL, Au-Yeung KK, House J, OK. Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney. Am J Physiol Renal Physiol 300: F189-F198, 2011.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Hwang, S.Y.1    Siow, Y.L.2    Au-Yeung, K.K.3    House, J.O.K.4
  • 18
    • 77953006982 scopus 로고    scopus 로고
    • Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China
    • Jiang Y, Zhao J, Jiang T, Ge L, Zhou F, Chen Z, Lei Y, Huang S, Xia B. Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China. J Gastroenterol Hepatol 25: 1157-1161, 2010.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1157-1161
    • Jiang, Y.1    Zhao, J.2    Jiang, T.3    Ge, L.4    Zhou, F.5    Chen, Z.6    Lei, Y.7    Huang, S.8    Xia, B.9
  • 19
    • 0033016881 scopus 로고    scopus 로고
    • Hemorrhagic shock results in intestinal muscularis intercellular adhesion molecule (ICAM-1) expression, neutrophil infiltration, and smooth muscle dysfunction
    • Kalff JC, Hierholzer C, Tsukada K, Billiar TR, Bauer AJ. Hemorrhagic shock results in intestinal muscularis intercellular adhesion molecule (ICAM-1) expression, neutrophil infiltration, and smooth muscle dysfunction. Arch Orthop Trauma Surg 119: 89-93, 1999.
    • (1999) Arch Orthop Trauma Surg , vol.119 , pp. 89-93
    • Kalff, J.C.1    Hierholzer, C.2    Tsukada, K.3    Billiar, T.R.4    Bauer, A.J.5
  • 20
    • 0346788981 scopus 로고    scopus 로고
    • The protective and healing effects of a natural antioxidant formulation based on ubiquinol and Aloe vera against dextran sulfate-induced ulcerative colitis in rats
    • Korkina L, Suprun M, Petrova A, Mikhalchik E, Luci A, De Luca C. The protective and healing effects of a natural antioxidant formulation based on ubiquinol and Aloe vera against dextran sulfate-induced ulcerative colitis in rats. Biofactors 18: 255-264, 2003.
    • (2003) Biofactors , vol.18 , pp. 255-264
    • Korkina, L.1    Suprun, M.2    Petrova, A.3    Mikhalchik, E.4    Luci, A.5    De Luca, C.6
  • 21
    • 33750609696 scopus 로고    scopus 로고
    • Recent trends in the epidemiology of inflammatory bowel diseases: Up or down?
    • Lakatos PL. Recent trends in the epidemiology of inflammatory bowel diseases: up or down? World J Gastroenterol 12: 6102-6108, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 6102-6108
    • Lakatos, P.L.1
  • 23
    • 49749130444 scopus 로고    scopus 로고
    • Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease
    • Manfredi MA, Zurakowski D, Rufo PA, Walker TR, Fox VL, Moses MA. Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis 14: 1091-1096, 2008.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1091-1096
    • Manfredi, M.A.1    Zurakowski, D.2    Rufo, P.A.3    Walker, T.R.4    Fox, V.L.5    Moses, M.A.6
  • 25
    • 33747626518 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in intestinal inflammation
    • Medina C, Radomski MW. Role of matrix metalloproteinases in intestinal inflammation. J Pharmacol Exp Ther 318: 933-938, 2006.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 933-938
    • Medina, C.1    Radomski, M.W.2
  • 27
    • 73349118462 scopus 로고    scopus 로고
    • MicroRNAs are involved in homocysteine-induced cardiac remodeling
    • Mishra PK, Tyagi N, Kundu S, Tyagi SC. MicroRNAs are involved in homocysteine-induced cardiac remodeling. Cell Biochem Biophys 55: 153-162, 2009.
    • (2009) Cell Biochem Biophys , vol.55 , pp. 153-162
    • Mishra, P.K.1    Tyagi, N.2    Kundu, S.3    Tyagi, S.C.4
  • 30
    • 80055017405 scopus 로고    scopus 로고
    • Meta-analysis: Hyperhomocysteinaemia in inflammatory bowel diseases
    • Oussalah A, Gueant JL, Peyrin-Biroulet L. Meta-analysis: hyperhomocysteinaemia in inflammatory bowel diseases. Aliment Pharmacol Ther 34: 1173-1184, 2011.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1173-1184
    • Oussalah, A.1    Gueant, J.L.2    Peyrin-Biroulet, L.3
  • 32
    • 0028845307 scopus 로고
    • Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
    • Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 346: 1395-1398, 1995.
    • (1995) Lancet , vol.346 , pp. 1395-1398
    • Perry, I.J.1    Refsum, H.2    Morris, R.W.3    Ebrahim, S.B.4    Ueland, P.M.5    Shaper, A.G.6
  • 35
    • 0034933207 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and inflammatory bowel disease: Prevalence and predictors in a cross-sectional study
    • Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M. Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study. Am J Gastroenterol 96: 2143-2149, 2001.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2143-2149
    • Romagnuolo, J.1    Fedorak, R.N.2    Dias, V.C.3    Bamforth, F.4    Teltscher, M.5
  • 37
    • 27744537688 scopus 로고    scopus 로고
    • Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro
    • Schroecksnadel K, Winkler C, Wirleitner B, Schennach H, Weiss G, Fuchs D. Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro. Clin Chem Lab Med 43: 1084-1088, 2005.
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1084-1088
    • Schroecksnadel, K.1    Winkler, C.2    Wirleitner, B.3    Schennach, H.4    Weiss, G.5    Fuchs, D.6
  • 38
    • 37149018726 scopus 로고    scopus 로고
    • Cystathionine-beta-synthase gene transfer and 3-deazaadenosine amelio-rate inflammatory response in endothelial cells
    • Sen U, Tyagi N, Kumar M, Moshal KS, Rodriguez WE, Tyagi SC. Cystathionine-beta-synthase gene transfer and 3-deazaadenosine amelio-rate inflammatory response in endothelial cells. Am J Physiol Cell Physiol 293: C1779-C1787, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Sen, U.1    Tyagi, N.2    Kumar, M.3    Moshal, K.S.4    Rodriguez, W.E.5    Tyagi, S.C.6
  • 39
    • 77956753730 scopus 로고    scopus 로고
    • Colon lengthening slows transit: Is this the mechanism underlying redundant colon or slow transit constipation?
    • Southwell BR. Colon lengthening slows transit: is this the mechanism underlying redundant colon or slow transit constipation? J Physiol 588: 3343, 2010.
    • (2010) J Physiol , vol.588 , pp. 3343
    • Southwell, B.R.1
  • 40
    • 77955774341 scopus 로고    scopus 로고
    • The status of vitamins B6, B12, folate, and of homocysteine in geriatric home residents receiving laxatives or dietary fiber
    • Sturtzel B, Dietrich A, Wagner KH, Gisinger C, Elmadfa I. The status of vitamins B6, B12, folate, and of homocysteine in geriatric home residents receiving laxatives or dietary fiber. J Nutr Health Aging 14: 219-223, 2010.
    • (2010) J Nutr Health Aging , vol.14 , pp. 219-223
    • Sturtzel, B.1    Dietrich, A.2    Wagner, K.H.3    Gisinger, C.4    Elmadfa, I.5
  • 42
    • 34247596041 scopus 로고    scopus 로고
    • Ciglitazone ameliorates homocysteine-mediated mitochondrial translocation and matrix metalloproteinase-9 activation in endothelial cells by inducing peroxisome proliferator activated receptor-gamma activity
    • Tyagi N, Moshal KS, Sen U, Lominadze D, Ovechkin AV, Tyagi SC. Ciglitazone ameliorates homocysteine-mediated mitochondrial translocation and matrix metalloproteinase-9 activation in endothelial cells by inducing peroxisome proliferator activated receptor-gamma activity. Cell Mol Biol (Noisy-le-grand) 52: 21-27, 2006.
    • (2006) Cell Mol Biol (Noisy-le-grand) , vol.52 , pp. 21-27
    • Tyagi, N.1    Moshal, K.S.2    Sen, U.3    Lominadze, D.4    Ovechkin, A.V.5    Tyagi, S.C.6
  • 44
    • 0037281357 scopus 로고    scopus 로고
    • Homocysteine stimulates inducible nitric oxide synthase expression in macrophages: Antagonizing effect of ginkgolides and bilobalide
    • Woo CW, Cheung F, Chan VW, Siow YL, OK. Homocysteine stimulates inducible nitric oxide synthase expression in macrophages: antagonizing effect of ginkgolides and bilobalide. Mol Cell Biochem 243: 37-47, 2003.
    • (2003) Mol Cell Biochem , vol.243 , pp. 37-47
    • Woo, C.W.1    Cheung, F.2    Chan, V.W.3    Siow, Y.L.O.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.