Leishmania (V.) braziliensis and L. (L.) amazonensis promote differential expression of dendritic cells and cellular immune response in murine model

Parasite Immunology

Volumn 34, Issue 8-9, 2012, Pages 395-403

  Carvalho, A K ^a   Silveira, F T ^b,c   Passero, L F D ^a   Gomes, C M C ^a   Corbett, C E P ^a   Laurenti, M D ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO EVANDRO CHAGAS   (Brazil)

^c FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

BALB c mice infection; Dermal dendritic cell; Langerhans cell; Leishmania (L.) amazonensis; Leishmania (V.) braziliensis; Th1 Th2 immune responses

Indexed keywords

GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 10; INTERLEUKIN 4; LANGERIN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DENSITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; EXPERIMENTAL MODEL; HUMAN; LANGERHANS CELL; LEISHMANIA; LEISHMANIA BRAZILIENSIS; LEISHMANIASIS; LYMPH NODE; MOUSE; NONHUMAN; PARASITE LOAD; PRIORITY JOURNAL; SKIN BIOPSY; SKIN CELL;

ANIMALS; ANTIGENS, CD; BIOPSY; CYTOKINES; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; LEISHMANIA BRAZILIENSIS; LEISHMANIA MEXICANA; LEISHMANIASIS; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE TYPE II; PARASITE LOAD; SKIN; TIME FACTORS;

LEISHMANIA AMAZONENSIS; LEISHMANIA BRAZILIENSIS; MURINAE; MUS;

EID: 84864763407     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2012.01370.x     Document Type: Article

References (30)

1. Lainson R & Shaw JJ. In Topley & Wilson's Microbiology and Microbial Infections Leishmaniasis v.5. In Collier L, Balows A & Sussman M (eds): London: Edward Arnold, 10th edn, 2005; 313-349.
2. Silveira FT, Lainson R & Corbett CEP. In: Tratado de Dermatologia v.1. Belda W Jr, Di Chiacchio N & Criado PR (eds): São Paulo, Atheneu; 2010; 1423-1455.
3. Silveira FT, Lainson R & Corbett CEP. Clinical and immunopathological spectrum of American cutaneous leishmaniasis with special reference to the disease in Amazonian Brazil: a review. Mem Inst Oswaldo Cruz 2004; 99: 239-251.
4. Silveira FT, Lainson R, Gomes CMC, Laurenti MD & Corbett CEP. Reviewwing the role of dendritic Langerhans cells in the immunopathogenesis of American cutaneous leishmaniasis. Trans R Soc Trop Med Hyg 2008; 102: 1074-1080.
5. Silveira FT, Lainson R, Gomes CMC, Laurenti MD & Corbett CEP. Immunopathogenic competences of Leishmania (V.) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis. Parasite Immunol 2009; 31: 423-431.
6. Blackwell JM. Tumour necrosis factor alpha and mucocutaneous leishmaniasis. Parasitol Today 1999; 15: 73-76.
7. Castellucci L, Menezes E, Oliveira J, et al. IL6-174G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. J Inf Dis 2007; 194: 519-527.
8. De CruesA, Beneden KV, Taghon T, et al. Langerans cells that have matured in vivo in the absence of T cells are fully capable of inducing a helper CD4 as well as a cytotoxic CD8 response. J Immunol 2000; 165: 645-653.
9. Ritter U, Meissner A, Scheidig C & Körner H. CD8a- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis. Eur J Immunol 2004; 34: 1542-1550.
10. Moll H. Epidermal Langerhans cells are critical for immunoregulation of cutaneous leishmaniasis. Immunol Today 1993; 23: 1595-1601.
11. Moll H, Flohé S & Rollinghoff M. Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T-cell immune response. Eur J Immunol 1995; 25: 693-699.
12. + T cells in experimental leishmaniasis is initiated by different dendritic cell subtypes. J Immunol 2009; 182: 774-783.
13. Kautz-Neu K, Noordegraaf M, Dinges S, et al. Langerhans cells are negative regulators of the anti-Leishmania response. J Exp Med 2011; 208: 885-891.
14. Shaw JJ, Ishikawa EA & Laison R. A rapid and sensitive method for the identification of Leishmania with monoclonal antibodies using fluorescein labelled-avidin. Trans R Soc Trop Med Hyg 1989; 83: 783-784.
15. Miles MA, Póvoa MM, de Souza AA, Laison R & Shaw JJ. Some methods for the enzymic characterization of Latin-America Leishmania with particular reference to Leishmania mexicana amazonensis and subspecies of Leishmania hertigi. Trans R Soc Med Hyg 1980; 74: 243-252.
16. Passero LFD, Marques C, Vale-Gato I, Corbett CEP, Laurenti MD & Santos Gomes G. Histopatology, humoral and cellular immune response in the murine model of Leishmania Viannia shawi. Parasitol Int 2010; 59: 159-165.
17. Passero LFD, Carvalho AK, Bordon MLAC, et al. Proteins of Leishmania (Viannia) shawi confer protection associated with Th1 immune response and memory generation. Parasites Vectors 2012; 5: 64.
18. Soong L. Modulation of dendritic cells function by Leishmania parasites. J Immunol 2008; 180: 4355-4360.
19. Ritter U & Osterloh A. A new view on cutaneous dendritic cell subsets in experimental leishmaniasis. Med Microbiol Immunol 2007; 196: 51-59.
20. Favali C, Tavares N, Clarêncio J, Barral A, Barral-Neto M & Brodskyn C. Leishmania amazonensis infection impairs differentiation and function of human dendritic cells. J Leukoc Biol 2007; 82: 1401-1406.
21. + T cells in vitro and in vivo. Infect Immun 2007; 75: 5018-5026.
22. Xin L & Soong L. Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol Immunol 2008; 45: 3371-3382.
23. Carvalho LP, Pearce EJ & Scott P. Functional dichotomy of dendritic cells following interaction with Leishmania braziliensis: infected cells produce high levels of TNFa, whereas bystander dendritic cells are activated to promote T cell response. J Immunol 2008; 181: 6473-6480.
24. Vargas-Inchaustegui DA, Xin L & Soong L. Leishmania braziliensis infection induces dendritic cells activation, ISG15 transcription and the generation of protective immune response. J Immunol 2008; 180: 7537-7545.
25. Qi H, Popov V & Soong L. Leishmania amazonensis-dendritic cell interactions in vitro and the priming of parasite-specific CD4+T cells in vivo. J Immunol 2001; 167: 4534-4542.
26. Herath S, Kropf P & Müller I. Cross-talk between CD8+ and CD4+ T cells in experimental cutaneous leishmaniasis: CD8+ T cells are required for optimal IFN-γ production by CD4+ T cells. Parasite Immunol 2003; 11-12: 559-567.
27. Ruiz JH & Becker I. CD8 cytotoxic T cells in cutaneous leishmaniasis. Parasite Immunol 2007; 29: 671-678.
28. Melief C. Regulation of T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming? Eur J Immunol 2003; 33: 1645-1654.
29. Müller I, Pedrazzini T, Kropf P, Louis J & Milon G. Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells. Int Immunol 1991; 3: 587-597.
30. Qi H, Ji J, Wanasen N & Soong L. Enhanced replication of Leishmania amazonensis amastigotes in gamma interferon-stimulated murine macrophages: implications for the pathogenesis of cutaneous leishmaniasis. Infect Immun 2004; 72: 988-995.