Reviewing the role of the dendritic Langerhans cells in the immunopathogenesis of American cutaneous leishmaniasis

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 102, Issue 11, 2008, Pages 1075-1080

  Silveira, Fernando T ^a,b   Lainson, Ralph ^a   Gomes, Claudia M C ^c   Laurenti, Márcia D ^c   Corbett, Carlos E P ^c  

^a INSTITUTO EVANDRO CHAGAS   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

American cutaneous leishmaniasis; Brazil; Dendritic Langerhans cells; Immunopathogenesis; Leishmania (Leishmania) amazonensis; Leishmania (Viannia) braziliensis

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 4; MESSENGER RNA;

CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; GENE EXPRESSION; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; LANGERHANS CELL; LEISHMANIA; LEISHMANIA BRAZILIENSIS; NONHUMAN; PARASITE IMMUNITY; REVIEW; SKIN LEISHMANIASIS; SPECIES DIFFERENCE; TH1 CELL; TH2 CELL;

ANIMALS; ANTIBODIES, PROTOZOAN; BRAZIL; HOST-PARASITE INTERACTIONS; HUMANS; LANGERHANS CELLS; LEISHMANIA; LEISHMANIASIS, CUTANEOUS; T-LYMPHOCYTES;

LEISHMANIA AMAZONENSIS; LEISHMANIA BRAZILIENSIS;

EID: 53549117126     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2008.05.020     Document Type: Review

References (40)

1. Barral A., Costa J.M.L., Bittencourt A.L., Barral-Neto M., and Carvalho E.M. Polar and subpolar diffuse cutaneous leishmaniasis in Brazil: clinical and immunopathologic aspects. Int. J. Dermatol. 34 (1995) 474-479
2. Blackwell J.M. Tumour necrosis factor alpha and mucocutaneous leishmaniasis. Parasitol. Today 15 (1999) 73-76
3. Bonfim G., Nascimento C., Costa J.M.L., Carvalho E.M., Barral-Neto M., and Barral A. Variation of cytokine patterns related to therapeutic response in diffuse cutaneous leishmaniasis. Exp. Parasitol. 84 (1996) 188-194
4. Cáceres-Dittmar G., Tapia F.J., Sanchez M.A., Yamamura M., Uyemura K., Modlin R.L., Bloom B.R., and Convit J. Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction. Clin. Exp. Immunol. 91 (1993) 500-505
5. Carvalho E.M., Barral A., Costa J.M.L., Bittencourt A., and Marsden P.D. Clinical and immunopathological aspects of disseminated cutaneous leishmaniasis. Acta Trop. 56 (1994) 315-325
6. Carvalho E.M., Correia-Filho D., Baccelar O., Lessa H., and Rocha H. Characterization of the immune response in subjects with self-healing cutaneous leishmaniasis. Am. J. Trop. Med. Hyg. 53 (1995) 273-277
7. Castellucci L., Menezes E., Oliveira J., Magalhães A., Guimarães L.H., Lessa M., Ribeiro S., Reale J., Noronha E.F., Wilson M.E., Duggal P., Beaty T.H., Jerônimo S., Jamieson S.E., Bales A., Blackwell J.M., de Jesus A.R., and Carvalho E.M. IL6-174 G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. J. Infect. Dis. 194 (2007) 519-527
8. Castes M., Trujilho D., Calgano M., Cabrera M., and Convit J. Response Th1/Th2 in human American cutaneous leishmaniasis: its possible relevance for the design of a vaccine. Mem. Inst. Oswaldo Cruz 88 (1993) 42-43
9. Convit J., Ulrich M., Fernandez C.T., Tapia F.J., Cáceres-Dittmar G., Cástes M., and Rondon A.J. The clinical and immunological spectrum of American cutaneous leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 87 (1993) 444-448
10. Costa J.M.L., Marsden P.D., Llanos-Cuentas E.A., Netto E.M., Carvalho E.M., Barral A., Rosa A.C., Cuba C.C., Magalhães A.V., and Barreto A.C. Disseminated cutaneous leishmaniasis in a field clinic in Bahia, Brazil: a report of eight cases. Am. J. Trop. Med. Hyg. 89 (1986) 319-321
11. Da-Cruz A.M., De-Oliveira M.P., De-Luca P.M., Mendonça S.C., and Coutinho S.G. Tumor necrosis fator-alpha in human American tegumentary leishmaniasis. Mem. Inst. Oswaldo Cruz 91 (1996) 225-229
12. Favali C., Tavares N., Clarêncio J., Barral A., Barral-Neto M., and Brodskyn C. Leishmania amazonensis infection impairs differentiation and function of human dendritic cells. J. Leukocyte Biol. 82 (2007) 1-6
13. Girolomoni G., Caux C., Lebecque S., Dezutter-Dambuyant C., and Ricciardi-Castagnoli P. Langerhans cells: still a fundamental paradigm for studying the immunobiology of dendritic cells. Trends Immunol. 23 (2002) 6-8
14. Guermonprez P., Valladeau J., Zitvogel L., Thery C., and Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20 (2002) 621-667
15. Ji J., Sun J., and Soong L. Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Infect. Immun. 71 (2003) 4278-4288
16. Ji J., Masterson J., Sun J., and Soong L. Regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection. J. Immunol. 174 (2005) 7147-7153
17. Kaplan D.H., Jenison M.C., Saeland S., Shlomchik W.D., and Shlomchik M.J. Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 23 (2005) 611-620
18. Katz S.I., Tamaki K., and Sachs D.H. Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature 282 (1979) 324-326
19. Kissenpfennig A., and Malissen B. Langerhans cells - revisiting the paradigm using genetically engineered mice. Trends Immunol. 27 (2006) 132-139
20. Lainson R., and Shaw J.J. Evolution, classification and geographical distribution. In: Peters W., and Killick-Kendrick R. (Eds). The Leishmaniases in Biology and Medicine vol. 1 (1987), Academic Press, London 1-120
21. Lainson, R., Shaw, J.J., 2005. Leishmaniasis in the New World, in: Collier, L., Balows, A., Sussman, M. (Eds), Topley & Wilson's Microbiology and Microbial Infections, vol. 5. Parasitology, tenth ed. Arnold, London, pp. 313-349.
22. Lainson R., Shaw J.J., Silveira F.T., Braga R.R., Ryan L., Povoa M.M., and Ishikawa E.A.I. A Leishmania e as leishmanioses. Instituto Evandro Chagas; 50 Anos de Contribuição às Ciências Biológicas e à Medicina Tropical (1986), Fundação Serviços de Saúde Pública, Belém, Pará, Brazil 83-124
23. Moll H. Epidermal Langerhans cells are critical for immunoregulation of cutaneous leishmaniasis. Immunol. Today 23 (1993) 1595-1601
24. Moll H., Flohé S., and Rollinghoff M. Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antingen-specific T-cell immune response. Eur. J. Immunol. 25 (1995) 693-699
25. Palucka A.K., and Banchereau J. Langerhans cells: daughters of monocytes. Nat. Immunol. 7 (2006) 223-224
26. Petersen E.A., Neva F.A., Oster C.N., and Diaz H.B. Specific inhibition of lymphocyte proliferation response by adherent suppressor cells in diffuse cutaneous leishmaniasis. N. Engl. J. Med. 306 (1982) 387-391
27. Pirmez C., Yamamura M., Uyemura K., Paes-Oliveira M., Conceição-Silva F., and Modlin R.L. Cytokine patterns in the pathogenegis of human leishmaniasis. J. Clin. Invest. 91 (1993) 1390-1395
28. Ribeiro-de-Jesus A., Almeida R.P., Lessa H., Baccelar O., and Carvalho E.M. Cytokine profile and pathology in human leishmaniasis. Braz. J. Med. Biol. Res. 31 (1998) 143-148
29. Ritter U., and Osterloh A. A new view on cutaneous dendritic cell subsets in experimental leishmaniasis. Med. Microbiol. Immunol. 196 (2007) 51-59
30. Ritter U., Moll H., Laskay T., Bröcker E.-B., Velazco O., Becker I., and Gillitzer R. Differential expression of chemokines in patients with localized and diffuse cutaneous American leishmaniasis. J. Infect. Dis. 173 (1996) 699-709
31. Ritter U., Meissner A., Scheidig C., and Körner H. CD8α- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis. Eur. J. Immunol. 34 (2004) 1542-1550
32. Silveira F.T., Lainson R., Shaw J.J., Garcez L.M., de Souza A.A.A., Braga R.R., and Ishikawa E.A.I. Experimental skin leishmaniasis: II. The course of infection in Cebus appella monkey (Primates: Cebidae) by Leishmania (V.) braziliensis and L. (L.) amazonensis. Rev. Soc. Bras. Med. Trop. 23 (1990) 5-12
33. Silveira F.T., Lainson R., Shaw J.J., de Souza A.A.A., Ishikawa E.A., and Braga R.R. Cutaneous leishmaniasis due to Leishmania (Leishmania) amazonensis in Amazonian Brazil, and the significance of a negative Montenegro skin test in human infections. Trans. R. Soc. Trop. Med. Hyg. 85 (1991) 735-738
34. Silveira F.T., Lainson R., de Brito A.C., Oliveira M.R.F., Paes M.G., De Souza A.A.A., and Da Silva B.M. Leishmaniose Tegumentar Americana. In: Leão R.N.Q. (Ed). Doenças Infecciosas e Parasitárias: Enfoque Amazônico (1997), Editora CEJUP, Belém, Pará, Brazil 619-630
35. Silveira F.T., Blackwell J.M., Ishikawa E.A., Braga R.R., Shaw J.J., Quinnell R.J., Soong L., Kima P., McMahon-Prat D., Black G.F., and Shaw M.A. T-cell responses to crude and defined leishmanial antigens in patients from the lower Amazon region of Brazil infected with different species of Leishmania of the subgenera Leishmania and Viannia. Parasite Immunol. 20 (1998) 19-26
36. Silveira F.T., Lainson R., and Corbett C.E.P. Clinical and immunopathological spectrum of American cutaneous leishmaniasis with special reference to the disease in Amazonian Brazil. Mem. Inst. Oswaldo Cruz 99 (2004) 239-251
37. Silveira F.T., Lainson R., and Corbett C.E.P. Further observations on clinical, histopathological and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis. Mem. Inst. Oswaldo Cruz 100 (2005) 525-534
38. Turetz M.L., Machado P.R., Ko A.I., Alves F., Bittencourt A., Almeida R.P., Mobashery N., Johnson Jr. W.D., and Carvalho E.M. Disseminated leishmaniasis: a new and emerging form of leishmaniasis observed in northeastern Brazil. J. Infect. Dis. 186 (2002) 1829-1834
39. Valladeau J., Ravel O., and Dezutter-Dambuyant C. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 12 (2000) 71-81
40. Xavier M.B., Silveira F.T., Demachki S., Ferrreira M.M.R., and Nascimento J.L. American tegumentary leishmaniasis: a quantitative analysis of Langerhans cells presents important differences between L. (L.) amazonensis and Viannia subgenus. Acta Trop. 95 (2005) 67-73