-
1
-
-
0035671925
-
Genistein elicits pleiotropic molecular effects on head and neck cancer cells
-
Alhasan SA, Aranha O, Sarkar FH. 2001. Genistein elicits pleiotropic molecular effects on head and neck cancer cells. Clin Cancer Res 7: 4174-4181.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4174-4181
-
-
Alhasan, S.A.1
Aranha, O.2
Sarkar, F.H.3
-
2
-
-
0033789914
-
Genistein: Does it prevent or promote breast cancer?
-
Bouker KB, Hilakivi-Clarke L. 2000. Genistein: Does it prevent or promote breast cancer? Environ Health Perspect 108: 701-708.
-
(2000)
Environ Health Perspect
, vol.108
, pp. 701-708
-
-
Bouker, K.B.1
Hilakivi-Clarke, L.2
-
3
-
-
0034631517
-
p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells
-
Casagrande F, Darbon JM. 2000. p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells. Exp Cell Res 258: 101-108.
-
(2000)
Exp Cell Res
, vol.258
, pp. 101-108
-
-
Casagrande, F.1
Darbon, J.M.2
-
4
-
-
0037968936
-
Inhibitory actions of genistein in human breast cancer (MCF-7) cells
-
Chen WF, Huang MH, Tzang CH, Yang M, Wong MS. 2003. Inhibitory actions of genistein in human breast cancer (MCF-7) cells. Biochim Biophys Acta 1638: 187-196.
-
(2003)
Biochim Biophys Acta
, vol.1638
, pp. 187-196
-
-
Chen, W.F.1
Huang, M.H.2
Tzang, C.H.3
Yang, M.4
Wong, M.S.5
-
5
-
-
0347335811
-
Pleotropic effects of genistein on MCF-7 breast cancer cells
-
Chinni SR, Alhasan SA, Multani AS, Pathak S, Sarkar FH. 2003. Pleotropic effects of genistein on MCF-7 breast cancer cells. Int J Mol Med 12: 29-34.
-
(2003)
Int J Mol Med
, vol.12
, pp. 29-34
-
-
Chinni, S.R.1
Alhasan, S.A.2
Multani, A.S.3
Pathak, S.4
Sarkar, F.H.5
-
6
-
-
0342980276
-
p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells
-
Choi YH, Lee WH, Park KY, Zhang L. 2000. p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells. Jpn J Cancer Res 91: 164-173.
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 164-173
-
-
Choi, Y.H.1
Lee, W.H.2
Park, K.Y.3
Zhang, L.4
-
7
-
-
0034685756
-
Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells
-
Darbon JM, Penary M, Escalas N, Casagrande F, Goubin-Gramatica F, Baudouin C, Ducommun B. 2000. Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells. J Biol Chem 275: 15363-15369.
-
(2000)
J Biol Chem
, vol.275
, pp. 15363-15369
-
-
Darbon, J.M.1
Penary, M.2
Escalas, N.3
Casagrande, F.4
Goubin-Gramatica, F.5
Baudouin, C.6
Ducommun, B.7
-
8
-
-
2342450536
-
Reproductive toxicity assessment of chronic dietary exposure to soy isoflavones in male rats
-
Faqi AS, Johnson WD, Morrissey RL, McCormick DL. 2004. Reproductive toxicity assessment of chronic dietary exposure to soy isoflavones in male rats. Reprod Toxicol 18: 605-611.
-
(2004)
Reprod Toxicol
, vol.18
, pp. 605-611
-
-
Faqi, A.S.1
Johnson, W.D.2
Morrissey, R.L.3
McCormick, D.L.4
-
9
-
-
34250213433
-
Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer
-
Farina HG, Pomies M, Alonso DF, Gomez DE. 2006. Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer. Oncol Rep 16: 885-891.
-
(2006)
Oncol Rep
, vol.16
, pp. 885-891
-
-
Farina, H.G.1
Pomies, M.2
Alonso, D.F.3
Gomez, D.E.4
-
10
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, Adams RR, Chang E, Allsopp RC, Yu J. 1995. The RNA component of human telomerase. Science 269: 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.S.3
Weinrich, S.L.4
Avilion, A.A.5
Chiu, C.P.6
Adams, R.R.7
Chang, E.8
Allsopp, R.C.9
Yu, J.10
-
11
-
-
0023663881
-
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
-
Greider CW, Blackburn EH. 1987. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51: 887-898.
-
(1987)
Cell
, vol.51
, pp. 887-898
-
-
Greider, C.W.1
Blackburn, E.H.2
-
12
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
-
Greider CW, Blackburn EH. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337: 331-337.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
13
-
-
33645992449
-
Gene expression profile changes correlating with radioresistance in human cell lines
-
Ishikawa K, Koyama-Saegusa K, Otsuka Y, Ishikawa A, Kawai S, Yasuda K, Suga T, Michikawa Y, Suzuki M, Iwakawa M, Imai T. 2006. Gene expression profile changes correlating with radioresistance in human cell lines. Int J Radiat Oncol Biol Phys 65: 234-245.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, pp. 234-245
-
-
Ishikawa, K.1
Koyama-Saegusa, K.2
Otsuka, Y.3
Ishikawa, A.4
Kawai, S.5
Yasuda, K.6
Suga, T.7
Michikawa, Y.8
Suzuki, M.9
Iwakawa, M.10
Imai, T.11
-
14
-
-
33644512054
-
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells
-
Jagadeesh S, Kyo S, Banerjee PP. 2006. Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells. Cancer Res 66: 2107-2115.
-
(2006)
Cancer Res
, vol.66
, pp. 2107-2115
-
-
Jagadeesh, S.1
Kyo, S.2
Banerjee, P.P.3
-
15
-
-
34547493433
-
Disruption of the developing female reproductive system by phytoestrogens: genistein as an example
-
Jefferson WN, Padilla-Banks E, Newbold RR. 2007. Disruption of the developing female reproductive system by phytoestrogens: genistein as an example. Mol Nutr Food Res 51: 832-844.
-
(2007)
Mol Nutr Food Res
, vol.51
, pp. 832-844
-
-
Jefferson, W.N.1
Padilla-Banks, E.2
Newbold, R.R.3
-
16
-
-
60849134580
-
Soy, isoflavones, and prostate cancer
-
Jian L. 2009. Soy, isoflavones, and prostate cancer. Mol Nutr Food Res 53: 217-226.
-
(2009)
Mol Nutr Food Res
, vol.53
, pp. 217-226
-
-
Jian, L.1
-
17
-
-
67349246450
-
Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells
-
Jin CY, Park C, Kim GY, Lee SJ, Kim WJ, Choi YH. 2009. Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells. Chem Biol Interact 180: 143-150.
-
(2009)
Chem Biol Interact
, vol.180
, pp. 143-150
-
-
Jin, C.Y.1
Park, C.2
Kim, G.Y.3
Lee, S.J.4
Kim, W.J.5
Choi, Y.H.6
-
18
-
-
20444452034
-
Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies
-
Keith WN, Bilsland A, Hardie M, Evans TR. 2004. Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies. Nat Clin Pract Oncol 1: 88-96.
-
(2004)
Nat Clin Pract Oncol
, vol.1
, pp. 88-96
-
-
Keith, W.N.1
Bilsland, A.2
Hardie, M.3
Evans, T.R.4
-
19
-
-
31044449825
-
Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: A possible mechanism of the growth inhibitory effect of Genistein
-
Kim EJ, Shin HK, Park JH. 2005. Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: A possible mechanism of the growth inhibitory effect of Genistein. J Med Food 8: 431-438.
-
(2005)
J Med Food
, vol.8
, pp. 431-438
-
-
Kim, E.J.1
Shin, H.K.2
Park, J.H.3
-
20
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
21
-
-
0034086069
-
Protection against breast cancer with genistein: A component of soy
-
Lamartiniere CA. 2000. Protection against breast cancer with genistein: A component of soy. Am J Clin Nutr 71: 1705S-1707S.
-
(2000)
Am J Clin Nutr
, vol.71
-
-
Lamartiniere, C.A.1
-
22
-
-
67449084948
-
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
-
Li Y, Liu L, Andrews LG, Tollefsbol TO. 2009. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125: 286-296.
-
(2009)
Int J Cancer
, vol.125
, pp. 286-296
-
-
Li, Y.1
Liu, L.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
23
-
-
50249177143
-
Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells
-
Li Z, Li J, Mo B, Hu C, Liu H, Qi H, Wang X, Xu J. 2008. Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells. Cell Biol Toxicol 24: 401-409.
-
(2008)
Cell Biol Toxicol
, vol.24
, pp. 401-409
-
-
Li, Z.1
Li, J.2
Mo, B.3
Hu, C.4
Liu, H.5
Qi, H.6
Wang, X.7
Xu, J.8
-
24
-
-
56249133327
-
Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids
-
Luo H, Jiang BH, King SM, Chen YC. 2008. Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids. Nutr Cancer 60: 800-809.
-
(2008)
Nutr Cancer
, vol.60
, pp. 800-809
-
-
Luo, H.1
Jiang, B.H.2
King, S.M.3
Chen, Y.C.4
-
25
-
-
42349103444
-
Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
-
Majid S, Kikuno N, Nelles J, Noonan E, Tanaka Y, Kawamoto K, Hirata H, Li LC, Zhao H, Okino ST, et al. 2008. Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. Cancer Res 68: 2736-2744.
-
(2008)
Cancer Res
, vol.68
, pp. 2736-2744
-
-
Majid, S.1
Kikuno, N.2
Nelles, J.3
Noonan, E.4
Tanaka, Y.5
Kawamoto, K.6
Hirata, H.7
Li, L.C.8
Zhao, H.9
Okino, S.T.10
-
26
-
-
0033518188
-
A telomerase component is defective in the human disease dyskeratosis congenita
-
Mitchell JR, Wood E, Collins K. 1999. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 402: 551-555.
-
(1999)
Nature
, vol.402
, pp. 551-555
-
-
Mitchell, J.R.1
Wood, E.2
Collins, K.3
-
27
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR. 1997. Telomerase catalytic subunit homologs from fission yeast and human. Science 277: 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
28
-
-
14744304811
-
Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity
-
Ouchi H, Ishiguro H, Ikeda N, Hori M, Kubota Y, Uemura H. 2005. Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity. Int J Urol 12: 73-80.
-
(2005)
Int J Urol
, vol.12
, pp. 73-80
-
-
Ouchi, H.1
Ishiguro, H.2
Ikeda, N.3
Hori, M.4
Kubota, Y.5
Uemura, H.6
-
29
-
-
36349005782
-
Anticancer therapy targeting telomeres and telomerase: Current status
-
Parkinson EK, Minty F. 2007. Anticancer therapy targeting telomeres and telomerase: Current status. BioDrugs 21: 375-385.
-
(2007)
BioDrugs
, vol.21
, pp. 375-385
-
-
Parkinson, E.K.1
Minty, F.2
-
30
-
-
33748453503
-
Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones
-
Puli S, Lai JC, Bhushan A. 2006. Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. J Neurooncol 79: 135-142.
-
(2006)
J Neurooncol
, vol.79
, pp. 135-142
-
-
Puli, S.1
Lai, J.C.2
Bhushan, A.3
-
31
-
-
33646727546
-
Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
-
Raffoul JJ, Wang Y, Kucuk O, Forman JD, Sarkar FH, Hillman GG. 2006. Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. BMC Cancer 6: 107.
-
(2006)
BMC Cancer
, vol.6
, pp. 107
-
-
Raffoul, J.J.1
Wang, Y.2
Kucuk, O.3
Forman, J.D.4
Sarkar, F.H.5
Hillman, G.G.6
-
32
-
-
58749100997
-
Effect of genistein-8-C-glucoside from Lupinus luteus on DNA damage assessed using the comet assay in vitro
-
Rucinska A, Gabryelak T. 2009. Effect of genistein-8-C-glucoside from Lupinus luteus on DNA damage assessed using the comet assay in vitro. Cell Biol Int 33: 247-252.
-
(2009)
Cell Biol Int
, vol.33
, pp. 247-252
-
-
Rucinska, A.1
Gabryelak, T.2
-
33
-
-
34548506071
-
Effect of the phytoestrogen, genistein-8-C-glucoside, on Chinese hamster ovary cells in vitro
-
Rucinska A, Kirko S, Gabryelak T. 2007. Effect of the phytoestrogen, genistein-8-C-glucoside, on Chinese hamster ovary cells in vitro. Cell Biol Int 31: 1371-1378.
-
(2007)
Cell Biol Int
, vol.31
, pp. 1371-1378
-
-
Rucinska, A.1
Kirko, S.2
Gabryelak, T.3
-
34
-
-
43849086499
-
The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines
-
Schmidt F, Knobbe CB, Frank B, Wolburg H, Weller M. 2008. The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines. Oncol Rep 19: 1061-1066.
-
(2008)
Oncol Rep
, vol.19
, pp. 1061-1066
-
-
Schmidt, F.1
Knobbe, C.B.2
Frank, B.3
Wolburg, H.4
Weller, M.5
-
35
-
-
42249099185
-
Genistein inhibits proliferation of human endometrial endothelial cell in vitro
-
Sha GH, Lin SQ. 2008. Genistein inhibits proliferation of human endometrial endothelial cell in vitro. Chin Med Sci J 23: 49-53.
-
(2008)
Chin Med Sci J
, vol.23
, pp. 49-53
-
-
Sha, G.H.1
Lin, S.Q.2
-
36
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S. 1997. A survey of telomerase activity in human cancer. Eur J Cancer 33: 787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
37
-
-
0036782884
-
Telomerase: A target for cancer therapeutics
-
Shay JW, Wright WE. 2002. Telomerase: A target for cancer therapeutics. Cancer Cell 2: 257-265.
-
(2002)
Cancer Cell
, vol.2
, pp. 257-265
-
-
Shay, J.W.1
Wright, W.E.2
-
38
-
-
12344288452
-
Mechanism-based combination telomerase inhibition therapy
-
Shay JW, Wright WE. 2005. Mechanism-based combination telomerase inhibition therapy. Cancer Cell 7: 1-2.
-
(2005)
Cancer Cell
, vol.7
, pp. 1-2
-
-
Shay, J.W.1
Wright, W.E.2
-
39
-
-
0025021235
-
Functional evidence for an RNA template in telomerase
-
Shippen-Lentz D, Blackburn EH. 1990. Functional evidence for an RNA template in telomerase. Science 247: 546-552.
-
(1990)
Science
, vol.247
, pp. 546-552
-
-
Shippen-Lentz, D.1
Blackburn, E.H.2
-
40
-
-
44949133877
-
Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status
-
Thasni KA, Rojini G, Rakesh SN, Ratheeshkumar T, Babu MS, Srinivas G, Banerji A, Srinivas P. 2008. Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status. Eur J Pharmacol 588: 158-164.
-
(2008)
Eur J Pharmacol
, vol.588
, pp. 158-164
-
-
Thasni, K.A.1
Rojini, G.2
Rakesh, S.N.3
Ratheeshkumar, T.4
Babu, M.S.5
Srinivas, G.6
Banerji, A.7
Srinivas, P.8
-
41
-
-
0034966374
-
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita
-
Vulliamy TJ, Knight SW, Mason PJ, Dokal I. 2001. Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita. Blood Cells Mol Dis 27: 353-357.
-
(2001)
Blood Cells Mol Dis
, vol.27
, pp. 353-357
-
-
Vulliamy, T.J.1
Knight, S.W.2
Mason, P.J.3
Dokal, I.4
-
42
-
-
0025279059
-
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
-
Yu GL, Bradley JD, Attardi LD, Blackburn EH. 1990. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature 344: 126-132.
-
(1990)
Nature
, vol.344
, pp. 126-132
-
-
Yu, G.L.1
Bradley, J.D.2
Attardi, L.D.3
Blackburn, E.H.4
-
43
-
-
44349141258
-
Genistein inhibits rat aortic smooth muscle cell proliferation through the induction of p27kip1
-
Yu JY, Lee JJ, Lim Y, Kim TJ, Jin YR, Sheen YY, Yun YP. 2008. Genistein inhibits rat aortic smooth muscle cell proliferation through the induction of p27kip1. J Pharmacol Sci 107: 90-98.
-
(2008)
J Pharmacol Sci
, vol.107
, pp. 90-98
-
-
Yu, J.Y.1
Lee, J.J.2
Lim, Y.3
Kim, T.J.4
Jin, Y.R.5
Sheen, Y.Y.6
Yun, Y.P.7
|