Taste masking of propiverine hydrochloride by conversion to its free base

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 8, 2012, Pages 976-984

  Ogata, Tetsuo ^a,b   Koide, Atsuo ^a   Kinoshita, Masahiro ^a   Ozeki, Tetsuya ^b  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Absorption study; Bitterness masking; Desalination; Dissolution test; Propiverine free base

Indexed keywords

PROPIVERINE;

ARTICLE; BITTER TASTE; DESALINATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG GRANULE; DRUG MANUFACTURE; DRUG SOLUBILITY; HUMAN; HUMAN EXPERIMENT; INFRARED SPECTROSCOPY; MALE; MASKING; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; NORMAL HUMAN; TABLET; TASTE MASKING; THERMOGRAVIMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ANIMALS; BENZILATES; BIOLOGICAL AVAILABILITY; CHOLINERGIC ANTAGONISTS; DOGS; MICROSCOPY, ELECTRON, SCANNING; POWDER DIFFRACTION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TASTE; THERMOGRAVIMETRY;

EID: 84864754084     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00206     Document Type: Article

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