Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice

European Journal of Immunology

Volumn 42, Issue 8, 2012, Pages 1999-2009

  Yoh, Keigyou ^a   Morito, Naoki ^a   Ojima, Masami ^a   Shibuya, Kazuko ^a   Yamashita, Yumi ^a   Morishima, Yuko ^b   Ishii, Yukio ^b   Kusakabe, Manabu ^a   Nishikii, Hidekazu ^a   Fujita, Akiko ^a   Matsunaga, Emi ^a   Okamura, Midori ^a   Hamada, Michito ^a   Suto, Akira ^c   Nakajima, Hiroshi ^c   Shibuya, Akira ^a   Yamagata, Kunihiro ^a   Takahashi, Satoru ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

Autoantibody; Plasmacytosis; ROR t; Th17; Thrombocytopenia

Indexed keywords

AUTOANTIBODY; CD11B ANTIGEN; CD2 ANTIGEN; DOUBLE STRANDED DNA ANTIBODY; ERYTHROCYTE ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; THROMBOCYTE ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HYPERIMMUNOGLOBULINEMIA; LIFESPAN; MACROPHAGE; MOUSE; NONHUMAN; PLASMA CELL; PLASMACYTOSIS; POLYCLONAL PLASMACYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SPLENOMEGALY; TRANSGENE;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD2; AUTOANTIBODIES; BLOOD PLATELETS; DNA; ERYTHROCYTES; INTERLEUKIN-17; INTERLEUKIN-6; LUNG; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PLASMA CELLS; PROMOTER REGIONS, GENETIC; PURPURA, HYPERGLOBULINEMIC; SPLENOMEGALY;

EID: 84864749535     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201142250     Document Type: Article

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