Global DNA methylation levels in white blood cell DNA from sisters discordant for breast cancer from the New York site of the breast cancer family registry

Epigenetics

Volumn 7, Issue 8, 2012, Pages 868-874

  Delgado Cruzata, Lissette ^a   Wu, Hui Chen ^a   Perrin, Mary ^b   Liao, Yuyan ^a   Kappil, Maya A ^a   Ferris, Jennifer S ^a   Flom, Julie D ^a   Yazici, Hulya ^c   Santella, Regina M ^a,d   Terry, Mary Beth ^a,d  

^a Mailman School of Public Health   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ISTANBUL UNIVERSITY   (Turkey)

^d New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

Breast cancer; Epigenetics; Global DNA methylation; LUMA; Methyl acceptance assay; White blood cells

Indexed keywords

BIOLOGICAL MARKER; DNA; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER REGISTRY; CANCER RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METHYLATION; EXAMINATION; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKOCYTE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; SIBLING; TWIN DISCORDANCE;

EID: 84864722475     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.20830     Document Type: Article

References (43)

1. Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604-10609; PMID:16009939; http://dx.doi.org/10.1073/pnas.0500398102.
2. Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr 2009; 21:243-251; PMID:19663042; http://dx.doi.org/10.1097/MOP.0b013e32832925cc.
3. Alves G, Tatro A, Fanning T. Differential methylation of human LINE-1 retrotransposons in malignant cells. Gene 1996; 176:39-44; PMID:8918229; http://dx.doi.org/10.1016/0378-1119(96)00205-3.
4. Florl AR, Löwer R, Schmitz-Dräger BJ, Schulz WA. DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas. Br J Cancer 1999; 80:1312-1321; PMID:10424731; http://dx.doi.org/10.1038/sj.bjc.6690524.
5. Lapeyre JN, Becker FF. 5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result. Biochem Biophys Res Commun 1979; 87:698-705; PMID:454420; http://dx.doi.org/10.1016/0006-291X(79)92015-1.
6. Lu LJ, Randerath E, Randerath K. DNA hypomethylation in Morris hepatomas. Cancer Lett 1983; 19:231-239; PMID:6192902; http://dx.doi.org/10.1016/0304-3835(83)90159-3.
7. Kulis M, Esteller M. DNA methylation and cancer. Adv Genet 2010; 70:27-56; PMID:20920744; http://dx.doi.org/10.1016/B978-0-12-380866-0.60002-2.
8. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998; 396:643-649; PMID:9872311; http://dx.doi.org/10.1038/25292.
9. Terry MB, Delgado-Cruzata L, Vin-Raviv N, Wu HC, Santella RM. DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics 2011; 6:828-837; PMID:21636973; http://dx.doi.org/10.4161/epi.6.7.16500.
10. Cash HL, Tao L, Yuan JM, Marsit CJ, Houseman EA, Xiang YB, et al. LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese. Int J Cancer 2012; 130:1151-1159; PMID:21445976; http://dx.doi.org/10.1002/ijc.26098.
11. Choi JY, James SR, Link PA, McCann SE, Hong CC, Davis W, et al. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis 2009; 30:1889-1897; PMID:19584139; http://dx.doi.org/10.1093/carcin/bgp143.
12. Hou L, Wang H, Sartori S, Gawron A, Lissowska J, Bollati V, et al. Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population. Int J Cancer 2010; 127:1866-1874; PMID:20099281; http://dx.doi.org/10.1002/ijc.25190.
13. Hsiung DT, Marsit CJ, Houseman EA, Eddy K, Furniss CS, McClean MD, et al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2007; 16:108-114; PMID:17220338; http://dx.doi.org/10.1158/1055-9965.EPI-06-0636.
14. Lim U, Flood A, Choi SW, Albanes D, Cross AJ, Schatzkin A, et al. Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women. Gastroenterology 2008; 134:47-55; PMID:18166347; http://dx.doi.org/10.1053/j.gastro.2007.10.013.
15. Moore LE, Pfeiffer RM, Poscablo C, Real FX, Kogevinas M, Silverman D, et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol 2008; 9:359-366; PMID:18339581; http://dx.doi.org/10.1016/S1470-2045(08)70038-X.
16. Pilsner JR, Hu H, Ettinger A, Sánchez BN, Wright RO, Cantonwine D, et al. Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ Health Perspect 2009; 117:1466-1471; PMID:19750115.
17. Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich V, Levy D, et al. Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr 2007; 86:1179-1186; PMID:17921400.
18. Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA 2008; 299:2877-2883; PMID:18577732; http://dx.doi.org/10.1001/jama.299.24.2877.
19. Deneberg S, Grövdal M, Karimi M, Jansson M, Nahi H, Corbacioglu A, et al. Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia. Leukemia 2010; 24:932-941; PMID:20237504; http://dx.doi.org/10.1038/leu.2010.41.
20. Lee JJ, Geli J, Larsson C, Wallin G, Karimi M, Zedenius J, et al. Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer. Int J Oncol 2008; 33:861-869; PMID:18813801.
21. Römermann D, Hasemeier B, Metzig K, Schlegelberger B, Länger F, Kreipe H, et al. Methylation status of LINE-1 sequences in patients with MDS or secondary AML. Verh Dtsch Ges Pathol 2007; 91:338-342; PMID:18314632.
22. Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, Litonjua AA, et al. Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control 2011; 22:437-447; PMID:21188491; http://dx.doi.org/10.1007/s10552-010-9715-2.
23. Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 2009; 5: 1000602; PMID:19680444; http://dx.doi.org/10.1371/journal.pgen.1000602.
24. Oakeley EJ. DNA methylation analysis: a review of current methodologies. Pharmacol Ther 1999; 84:389-400; PMID:10665836; http://dx.doi.org/10.1016/S0163-7258(99)00043-1.
25. Pufulete M, Al-Ghnaniem R, Leather AJ, Appleby P, Gout S, Terry C, et al. Folate status, genomic DNA hypomethylation and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 2003; 124:1240-1248; PMID:12730865; http://dx.doi.org/10.1016/S0016-5085(03)00279-8.
26. Wilhelm CS, Kelsey KT, Butler R, Plaza S, Gagne L, Zens MS, et al. Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res 2010; 16:1682-1689; PMID:20179218; http://dx.doi.org/10.1158/1078-0432.CCR-09-2983.
27. Yoder JA, Walsh CP, Bestor TH. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet 1997; 13:335-340; PMID:9260521; http://dx.doi.org/10.1016/S0168-9525(97)01181-5.
28. Wu HC, Delgado-Cruzata L, Flom JD, Kappil M, Ferris JS, Liao Y, et al. Global methylation profiles in DNA from different blood cell types. Epigenetics 2011; 6:76-85; PMID:20890131; http://dx.doi.org/10.4161/epi.6.1.13391.
29. Nelson HH, Marsit CJ, Kelsey KT. Global methylation in exposure biology and translational medical science. Environ Health Perspect 2011; 119:1528-1533; PMID:21669556; http://dx.doi.org/10.1289/ehp.1103423.
30. Balaghi M, Wagner C. DNA methylation in folate deficiency: use of CpG methylase. Biochem Biophys Res Commun 1993; 193:1184-1190; PMID:8323540; http://dx.doi.org/10.1006/bbrc.1993.1750.
31. Karimi M, Johansson S, Ekström TJ. Using LUMA: a Luminometric-based assay for global DNA-methylation. Epigenetics 2006; 1:45-48; PMID:17998810; http://dx.doi.org/10.4161/epi.1.1.2587.
32. Karimi M, Johansson S, Stach D, Corcoran M, Grandér D, Schalling M, et al. LUMA (LUminometric Methylation Assay)-a high throughput method to the analysis of genomic DNA methylation. Exp Cell Res 2006; 312:1989-1995; PMID:16624287; http://dx.doi.org/10.1016/j.yexcr.2006.03.006.
33. Basten GP, Duthie SJ, Pirie L, Vaughan N, Hill MH, Powers HJ. Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers. Br J Cancer 2006; 94:1942-1947; PMID:16736000; http://dx.doi.org/10.1038/sj.bjc.6603197.
34. Fenech M, Aitken C, Rinaldi J. Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults. Carcinogenesis 1998; 19:1163-1171; PMID:9683174; http://dx.doi.org/10.1093/carcin/19.7.1163.
35. Shelnutt KP, Kauwell GP, Gregory JF, 3rd, Maneval DR, Quinlivan EP, Theriaque DW, et al. Methylenetetrahydrofolate reductase 677C→T polymorphism affects DNA methylation in response to controlled folate intake in young women. J Nutr Biochem 2004; 15:554-560; PMID:15350988; http://dx.doi.org/10.1016/j.jnutbio.2004.04.003.
36. John EM, Hopper JL, Beck JC, Knight JA, Neuhausen SL, Senie RT, et al.; Breast Cancer Family Registry. The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer. Breast Cancer Res 2004; 6:375-389; PMID:15217505; http://dx.doi.org/10.1186/bcr801.
37. Zipprich J, Terry MB, Brandt-Rauf P, Freyer GA, Liao Y, Agrawal M, et al. XRCC1 polymorphisms and breast cancer risk from the New York Site of the Breast Cancer Family Registry: A family-based case-control study. J Carcinog 2010; 9:4; PMID:20442803; http://dx.doi.org/10.4103/1477-3163.62535.
38. Zipprich J, Terry MB, Liao Y, Agrawal M, Gurvich I, Senie R, et al. Plasma protein carbonyls and breast cancer risk in sisters discordant for breast cancer from the New York site of the Breast Cancer Family Registry. Cancer Res 2009; 69:2966-2972; PMID:19339271; http://dx.doi.org/10.1158/0008-5472.CAN-08-3418.
39. Machella N, Terry MB, Zipprich J, Gurvich I, Liao Y, Senie RT, et al. Double-strand breaks repair in lymphoblastoid cell lines from sisters discordant for breast cancer from the New York site of the BCFR. Carcinogenesis 2008; 29:1367-1372; PMID:18566018; http://dx.doi.org/10.1093/carcin/bgn140.
40. Kennedy DO, Agrawal M, Shen J, Terry MB, Zhang FF, Senie RT, et al. DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer. J Natl Cancer Inst 2005; 97:127-132; PMID:15657342; http://dx.doi.org/10.1093/jnci/dji013.
41. Shen J, Desai M, Agrawal M, Kennedy DO, Senie RT, Santella RM, et al. Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer. Cancer Epidemiol Biomarkers Prev 2006; 15:1614-1619; PMID:16985021; http://dx.doi.org/10.1158/1055-9965.EPI-06-0218.
42. Zeger SL, Liang KY, Albert PS. Models for longitudinal data: a generalized estimating equation approach. Biometrics 1988; 44:1049-1060; PMID:3233245; http://dx.doi.org/10.2307/2531734.
43. Wu HC, Delgado-Cruzata L, Flom JD, Perrin M, Liao Y, Ferris J, et al. Repetitive element SDNA methylation levels in white blood cell DNA from sisters discordant for breast cancer from the New York site of the BCFR. Carcinogenesis. 2012; In press; PMID: 22678115; http://dx.doi.org/10.1093/carcin/bgs201.