Serum amyloid A is a growth factor for 3T3-L1 adipocytes, inhibits differentiation and promotes insulin resistance

International Journal of Obesity

Volumn 36, Issue 8, 2012, Pages 1032-1039

  Filippin Monteiro, F B ^a   De Oliveira, E M ^a   Sandri, S ^a   Knebel, F H ^a   Albuquerque, R C ^a   Campa, A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

adipogenesis; inflammation; insulin resistance; preadipocyte; proliferation; Serum amyloid A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AMYLOID A PROTEIN; CCAAT ENHANCER BINDING PROTEIN BETA; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCEROL; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; THYMIDINE; TRITIUM; TUMOR NECROSIS FACTOR ALPHA;

ADIPOGENESIS; ARTICLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL LYSATE; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOKINE RELEASE; FLOW CYTOMETRY; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INSULIN RESISTANCE; LIPOLYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; DEOXYGLUCOSE; FLOW CYTOMETRY; HUMANS; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, OBESE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERUM AMYLOID A PROTEIN; UP-REGULATION;

EID: 84864717284     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2011.193     Document Type: Article

References (45)

1. Rodeheffer MS, Birsoy K, Friedman JM. Identification ofwhite adipocyte progenitor cells in vivo. Cell 2008; 135: 240-249.
2. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose-tissue expression of tumor-necrosis-factor-alpha in human obesity and insulin-resistance. J Clin Invest 1995; 95: 2409-2415.
3. Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006; 17: 4-12.
4. Scheja L, Heese B, Zitzer H, Michael MD, Siesky AM, Pospisil H et al. Acute-phase serum amyloid a as a marker of insulin resistance in mice. Exp Diabetes Res 2008; 2008: 230837.
5. Virkamaki A, Ueki K, Kahn CR. Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance.J Clin Invest 1999; 103: 931-943. (Pubitemid 29169600)
6. Yang RZ, Lee MJ, Hu H, Pollin TI, Ryan AS, Nicklas BJ et al. Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. Plos Medicine 2006; 3: 884-894.
7. Sjoholm K, Lundgren M, Olsson M, Eriksson JW. Association ofserum amyloid A levels with adipocyte size and serum levels of adipokines: differences between men and women. Cytokine 2009; 48: 260-266.
8. Urieli-Shoval S, Linke RP, Matzner Y. Expression and function ofserum amyloid A, a major acute-phase protein, in normal and disease states, 2000; 7: 64-69. (Pubitemid 30007690)
9. Jernas M, Palming J, Sjoholm K, Jennische E, Svensson PA, Gabrielsson BG et al. Separation of human adipocytes by size: hypertrophic fat cells display distinct gene expression. Faseb Journal 2006; 20: 1540.
10. Poitou C, Viguerie N, Cancello R, De Matteis R, Cinti S, Stich V et al. Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition. Diabetologia 2005; 48: 519-528. (Pubitemid 40487299)
11. Poitou C, Coussieu C, Rouault C, Coupaye M, Cancello R, Bedel JF et al. Serum amyloid A: a marker of adiposity-induced low-grade inflammation but not of metabolic status. Obesity 2006; 14: 309-318. (Pubitemid 46214763)
12. Sommer G, Weise S, Kralisch S, Scherer PE, Lossner U, Bluher M et al. The adipokine SAA3 is induced by interleukin-1 beta in mouse adipocytes. J Cell Biochem 2008; 104: 2241-2247.
13. Lin Y, Rajala MW, Berger JP, Moller DE, Barzilai N, Scherer PE. Hyperglycemia-induced production ofacute phase reactants in adipose tissue.J Biol Chem 2001; 276: 42077-42083.
14. Furlaneto CJ, Campa A. A novel function ofserum amyloid A: a potent stimulusfor the release of tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 by human blood neutrophil. Biochem Biophys Res Commun 2000; 268: 405-408. (Pubitemid 30119635)
15. Hatanaka E, Furlaneto CJ, Ribeiro FP, Souza GM, Campa A. Serum amyloid A-induced mRNA expression and release of tumor necrosis factor-alpha (TNF-alpha) in human neutrophils. Immunol Lett 2004; 91: 33-37. (Pubitemid 38147743)
16. Ribeiro FP, Furlaneto CJ, Hatanaka E, Ribeiro WB, Souza GM, Cassatella MA et al. mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes. Mediators Inflamm 2003; 12: 173-178. (Pubitemid 36871853)
17. Sandri S, Rodriguez D, Gomes E, Monteiro HP, Russo M, Campa A. Is serum amyloid A an endogenous TLR4 agonist? J Leukoc Biol 2008; 83: 1174-1180. (Pubitemid 351960349)
18. Hatanaka E, Monteagudo PT, Marrocos MSM, Campa A. Interaction between serum amyloid A and leukocytes-A possible role in the progression ofvascular complications in diabetes. Immunol Lett 2007; 108: 160-166. (Pubitemid 46198961)
19. Hatanaka E, Dermargos A, Armelin HA, Curi R, Campa A. Serum amyloid A induces reactive oxygen species (ROS) production and proliferation offibroblast. Clin Exp Immunol 2011; 163: 362-367.
20. Farmer SR. Regulation of PPAR gamma activity during adipogenesis. Int J Obes 2005; 29: S13-S16. (Pubitemid 40343165)
21. Hamm JK, Park BH, Farmer SR. A role for C/EBP beta in regulating peroxisome proliferator-activated receptor gamma activity during adipogenesis in 3T3-L1 preadipocytes. J Biol Chem 2001; 276: 18464-18471.
22. Kawai M, Sousa KM, MacDougald OA, Rosen CJ. The many facets of PPAR gamma: novel insights for the skeleton. Am J Physiol Endocrinol Metab 2010; 299: E3-E9.
23. Ye XY, Xue YM, Sha JP, Li CZ, Zhen ZJ. Serum amyloid A attenuates cellular insulin sensitivity by increasing JNK activity in 3T3-L1 adipocytes. J Endocrinol Invest 2009; 32: 568-575.
24. Moon HS, Chung CS, Lee HG, Kim TG, Choi YJ, Cho CS. Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of3T3-L1 cells. Obesity2007; 15: 2571-2582.
25. Zou C, Shen Z. One-step intracellular triglycerides extraction and quantitative measurement in vitro. J Pharmacol Toxicol Methods 2007; 56: 63-66. (Pubitemid 46829933)
26. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 2001; 25: 402-408. (Pubitemid 34164012)
27. Hsu HF, Tsou TC, Chao HR, Shy CG, Kuo YT, Tsai FY et al. Effects of arecoline on adipogenesis, lipolysis, and glucose uptake of adipocytes-A possible role of betel-quid chewing in metabolic syndrome. Toxicol Appl Pharmacol 2010; 245: 370-377.
28. Knebel FH, Albuquerque RC, Maria-Engler SS, Campa A. Dual effect of serum amyloid A protein on gliomas. Inflamm Res 2011; 60: 195-195.
29. Cleveland-Donovan K, Maile LA, Tsiaras WG, Tchkonia T, Kirkland JL, Boney CM. IGF-I activation of the AKT pathway is impaired in visceral but not subcutaneous preadipocytes from obese subjects. Endocrinology 2010; 151: 3752-3763.
30. Matthews LC, Taggart MJ, Westwood M. Modulation ofcaveolin-1 expression can affect signalling through the phosphatidylinositol 3-kinase/Akt pathway and cellular proliferation in response to insulin-like growth factor I. Endocrinology 2008; 149: 5199-5208.
31. Benito M, Valverde AM, Lorenzo M. IGF-I: A mitogen also involved in differentiation processes in mammalian cells. Int J Biochem Cell Biol1996; 28: 499-510.
32. Gagnon A, Dods P, Roustan-Delatour N, Chen CS, Sorisky A. Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of3T3-L1 preadipocytes. Endocrinology 2001; 142: 205-212. (Pubitemid 32183682)
33. Lee HY, Kim SD, Shim JW, Kim HJ, Yun J, Baek SH et al. A pertussis toxin sensitive G-protein-independent pathway is involved in serum amyloid A-induced formyl peptide receptor 2-mediated CCL2 production. ExpMol Med 2010; 42: 302-309.
34. Baranova IN, Vishnyakova TG, Bocharov AV, Kurlander R, Chen ZG, Kimelman ML et al. Serum amyloid a binding to CLA-1 (CD36 and LIMPII analogous-1) mediates serum amyloid A protein-induced activation of ERK1/2 and p38 mitogen-activated protein kinases. J Biol Chem 2005; 280: 8031-8040. (Pubitemid 40349701)
35. Du JL, Sun CK, Lü B, Men LL, Yao JJ, An LJ et al. Association of SelS mRNA expression in omental adipose tissue with Homa-IR and serum amyloid A in patients with type 2 diabetes mellitus. Chin Med J 2008; 121: 1165-1168.
36. Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nature Rev Mol Cell Biol 2006; 7: 885-896. (Pubitemid 44871415)
37. Gregoire FM, Smas CM, Sul HS. Understanding adipocyte differentiation. Physiol Rev 1998; 78: 783-809. (Pubitemid 28340604)
38. Sandri S, Hatanaka E, Franco AG, Pedrosa AMC, Monteiro HP, Campa A. Serum amyloid A induces CCL20 secretion in mononuclear cells through MAPK (p38 and ERK1/2) signaling pathways. Immunol Lett 2008; 121: 22-26.
39. Guilherme A, Tesz GJ, Guntur KVP, Czech MP. Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes. J Biol Chem 2009; 284: 17082-17091.
40. Souza SC, de Vargas LM, Yamamoto MT, Lien P, Franciosa MD, Moss LG et al. Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes. J Biol Chem 1998; 273: 24665-24669. (Pubitemid 28454965)
41. Lang CH, Dobrescu C, Bagby GJ. Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 1992; 130: 43-52.
42. Peraldi P, Spiegelman B. TNF-alpha and insulin resistance: summary and future prospects. Mol Cell Biochem 1998; 182: 169-175. (Pubitemid 28181660)
43. Langin D, Arner P. Importance of TNF alpha and neutral lipases in human adipose tissue lipolysis. Trends Endocrinol Metabol 2006; 17: 314-320. (Pubitemid 44419491)
44. Spiegelman BM, Arner P, Caro JF, Atkinson RL, Hotamisligil GS. Elevation of adipose-tissue expression of TNF-alpha and TNF receptors in human obesity and insulin-resistance. Diabetes 1995; 44: A45-A45.
45. Vassaux G, Negrel R, Ailhaud G, Gaillard D. Proliferation and differentiation of rat adipose precursor cells in chemically-defined medium-differential action of anti-adipogenic agents. J Cell Physiol 1994; 161: 249-256. (Pubitemid 24353553)