Novel polyvinylpyrrolidones to improve delivery of poorly water-soluble drugs: From design to synthesis and evaluation

Molecular Pharmaceutics

Volumn 9, Issue 8, 2012, Pages 2237-2247

  Niemczyk, Anna I ^a   Williams, Adrian C ^a   Rawlinson Malone, Clare F ^a,b   Hayes, Wayne ^a   Greenland, Barnaby W ^a   Chappell, David ^a   Khutoryanskaya, Olga ^a   Timmins, Peter ^b  

^a UNIVERSITY OF READING   (United Kingdom)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

amorphous; dissolution; hydrogen bonding; polyvinylpyrrolidone; poorly water soluble drugs

Indexed keywords

DISINTEGRATING AGENT; DRUG CARRIER; IBUPROFEN; POLYMER; POVIDONE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG SOLUBILITY; EVALUATION; HYDROGEN BOND; POLYMERIZATION; POROSITY; PRIORITY JOURNAL; SURFACE PROPERTY; SYNTHESIS;

DRUG CARRIERS; HYDROGEN BONDING; IBUPROFEN; POVIDONE; SOLUBILITY; WATER;

EID: 84864678524     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300079x     Document Type: Article

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