20-HETE agonists and antagonists in the renal circulation

American Journal of Physiology - Renal Physiology

Volumn 277, Issue 5 46-5, 1999, Pages

  Alonso Galicia, Magdalena ^a   Falck, John R ^b   Reddy, Komandla Malla ^b   Roman, Richard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cytochrome P 450; Hydroxyeicosatetraenoic acids; Renal arterioles; Vasoconstriction

Indexed keywords

HYDROXYICOSATETRAENOIC ACID;

ANIMAL TISSUE; ARTERIOLE; ARTERY DIAMETER; ARTICLE; BINDING SITE; BLOOD VESSEL REACTIVITY; CHEMICAL STRUCTURE; HYDROGEN BOND; KIDNEY CIRCULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; VASOCONSTRICTION;

EID: 0032760290     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.277.5.f790     Document Type: Article

References (34)

1. Alonso-Galicia, M., H. A. Drummond, K. M. Reddy, J. R. Falck, and R. J. Roman. Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension 29: 320-325, 1997.
2. Alonso-Galicia, M., A. S. Greene, T. M. Kurth, A. W. Cowley, and R. J. Roman. 20-HETE contributes to the renal vasoconstrictor actions of angiotensin II (Abstract). FASEB J. 13: 512, 1999.
3. Capdevila, J. H., J. R. Falck, and R. W. Eastbrook. Cytochrome P450 and the arachidonate cascade. FASEB J. 6: 731-736, 1992.
4. Frazier, L. W., and T. Yorio. Eicosanoids: their function in renal epithelia ion transport. Proc. Soc. Exp. Biol. Med. 201: 229-243, 1992.
5. 2+ currents. J. Physiol. (Lond.) 507: 771-781, 1998.
6. Harder, D. R., W. B. Campbell, and R. J. Roman. Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J. Vasc. Res. 32: 79-92, 1995.
7. Harder, D. R., A. R. Lange, D. Gebremedhin, E. K. Birks, and R. J. Roman. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J. Vasc. Res. 34: 237-243, 1997.
8. Harder, D. R., J. Narayanan, E. K. Birks, J. F. Liard, J. D. Imig, J. H. Lombard, A. R. Lange, and R. J. Roman. Identification of a putative microvascular oxygen sensor. Circ. Res. 79: 54-61, 1996.
9. Imaoka, S., N. Shimojo, and Y. Funae. Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. Biochem. Biophys. Res. Commun. 152: 680-687, 1988.
10. Imig, J. D., E. W. Inscho, P. C. Deichmann, K. M. Reddy, and J. R. Falck. Afferent arteriolar vasodilation to the sulfonimide analogue of 11, 12-epoxyeicosatrienoic acid involves protein kinase A. Hypertension 33: 408-413, 1999.
11. Imig, J. D., A. P. Zou, P. R. Ortiz de Montellano, Z. Sui, and R. J. Roman. Inhibitors of cytochrome P-450 alter afferent arteriolar responses to elevations in pressure. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1879-H1885, 1994.
12. Imig, J. D., A. P. Zou, D. E. Stec, D. R. Harder, and R. J. Roman. Formation and actions of 20-HETE by renal microvessels. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R217-R227, 1996.
13. Jacobs, E. R., R. M. Effros, J. R. Falck, K. M. Reddy, W. B. Campbell, and D. Zhu. Airway synthesis of 20-hydroxyeicosatetraenoic acid: metabolism by cyclooxygenase to a bronchodilator. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L280-L288, 1999.
14. Ca-channel activity by cyclic ADP-ribose and ADP-ribose in coronary arterial smooth muscle. Am. J. Physiol. 275 (Heart Circ. Physiol. 44): H1002-H1010, 1998.
15. Lin, F., A. Rios, J. R. Falck, Y. Belosludtsev, and M. L. Schwartzman. 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F806-F816, 1995.
16. 2 and prostacyclin. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H509-H516, 1999.
17. Ma, Y.-H., D. Gebremedhin, M. L. Schwartzman, J. E. Clark, D. R. Harder, B. S. Masters, and R. J. Roman. 20-HETE is an endogenous vasoconstrictor of dog renal arcuate arteries. Circ. Res. 72: 126-136, 1993.
18. Makita, K., J. R. Falck, and J. H. Capdevila. Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system. FASEB J. 10: 1456-1463, 1996.
19. McGiff, J. C. Cytochrome P450 metabolism of arachidonic acid. Annu. Rev. Pharmacol. Toxicol. 31: 339-369, 1991.
20. Ominato, M., T. Satoh, and A. I. Katz. Regulation of Na-K-ATPase activity in the proximal tubule: role of the protein kinase C pathway and of eicosanoids. J. Membr. Biol. 152: 235-243, 1996.
21. Oyekan, A. O., and J. C. McGiff. Cytochrome P-450-derived eicosanoids participate in the renal functional effects of ET-1 in the anesthetized rat. Am. J. Physiol. 274 (Regulatory Integrative Comp. Physiol. 43): R52-R61, 1998.
22. Rahman, M., J. T. Wright, and J. G. Douglas. The role of the cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function. A review. Am. J. Hypertens. 10: 356-365, 1997.
23. Roman, R. J., and M. Alonso-Galicia. P450 eicosanoids: a novel signaling pathway regulating renal function. NIPS. In press.
24. Roman, R. J., M. Alonso-Galicia, and T. W. Wilson. Renal P450 metabolites of arachidonic acid and the development of hypertension in Dahl salt-sensitive rats. Am. J. Hypertens. 10: 63S-67S, 1997.
25. Roman, R. J., J. R. Falck, M. Alonso-Galicia, E. R. Jacobs, and D. R. Harder. 20-HETE Agonists and Antagonists. Patent application USSN 60/076,091.
26. Sacerdoti, D., M. Balazy, P. Angeli, A. Gatta, and J. C. McGiff. Eicosanoid excretion in hepatic cirrhosis. Predominance of 20-HETE. J. Clin. Invest. 100: 1264-1270, 1997.
27. Sacerdoti, D., B. Escalante, N. G. Abraham, J. C. McGiff, R. D. Levere, and M. L. Schwartzman. Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. Science 243: 388-390, 1989.
28. Stec, D. E., M. R. Trolliet, J. E. Krieger, H. J. Jacob, and R. J. Roman. Renal cytochrome P4504A activity and salt sensitivity in spontaneously hypertensive rats. Hypertension 27: 1329-1336, 1996.
29. Sun, C. W., J. R. Falck, D. R. Harder, and R. J. Roman. Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. Hypertension 33: 414-418, 1999.
30. + channel may involve a G-protein dependent mechanism (Abstract). FASEB J. 11: 503, 1997.
31. Uddin, M. R., M. M. Muthalif, N. A. Karzoun, I. F. Benter, and K. U. Malik. Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling. Hypertension 31: 242-247, 1998.
32. +-channel in renal arterioles. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R228-R237, 1996.
33. Zou, A. P., J. D. Imig, M. L. Kaldunski, P. R. Ortiz de Montellano, Z. Sui, and R. J. Roman. Inhibition of renal vascular production of 20-hydroxyeicosatetraenoic acid impairs autoregulation of renal blood flow. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F275-F282, 1994.
34. Zou, A. P., J. D. Imig, P. R. Ortiz de Montellano, Z. Sui, J. R. Falck, and R. J. Roman. Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F934-F941, 1994.