Comparative homology modeling of pyruvate dehydrogenase kinase isozymes from Xenopus tropicalis reveals structural basis for their subfunctionalization

Journal of Molecular Modeling

Volumn 18, Issue 6, 2012, Pages 2567-2576

  Tokmakov, Alexander A ^a,b  

^a KOBE UNIVERSITY   (Japan)

^b RIKEN   (Japan)

Author keywords

Homology modeling; Isoforms; Pyruvate dehydrogenase kinase; Subfunctionalization; Xenopus tropicalis

Indexed keywords

NUCLEOTIDE; PYRUVATE DEHYDROGENASE KINASE;

AMINO ACID SEQUENCE; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; COMPARATIVE HOMOLOGY MODELING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; METABOLIC REGULATION; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; STRUCTURAL BIOINFORMATICS; TISSUE DISTRIBUTION; XENOPUS TROPICALIS;

AMINO ACID SEQUENCE; AMPHIBIAN PROTEINS; ANIMALS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; GENE EXPRESSION PROFILING; HYDROGEN BONDING; ISOENZYMES; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; STRUCTURAL HOMOLOGY, PROTEIN; SURFACE PROPERTIES; THERMODYNAMICS; XENOPUS;

MAMMALIA; XENOPUS TROPICALIS;

EID: 84864648298     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-011-1281-3     Document Type: Article

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