Practical large-scale preparation of (r)-rolipram using chiral nickel catalyst

Synthetic Communications

Volumn 42, Issue 22, 2012, Pages 3288-3295

  Wen, Lixin ^a,b   Tang, Feiyu ^a,c   Ge, Chengsheng ^a,c   Wang, Xiaodong ^c   Han, Zhi ^c   Wu, Jianyi ^a,b,d  

^a JIAXING UNIVERSITY   (China)

^b CHANGZHOU UNIVERSITY   (China)

^c Jiaxing Epochem Pharmtech Co Ltd   (China)

^d Key Laboratory of Clean Chemical Process of Jiaxing   (China)

Author keywords

(R) rolipram; Asymmetric synthesis; Michael addition

Indexed keywords

ANTIDEPRESSANT AGENT; NICKEL; ROLIPRAM;

ARTICLE; CATALYST; CHEMICAL REACTION; DRUG SYNTHESIS; LARGE SCALE PRODUCTION;

EID: 84864625056     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397911.2011.580880     Document Type: Article

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