Enhanced targeted anticancer effects and inhibition of tumor metastasis by the TMTP1 compound peptide TMTP1-TAT-NBD

Journal of Controlled Release

Volumn 161, Issue 3, 2012, Pages 893-902

  Liu, Ronghua ^a   Xi, Ling ^a   Luo, Danfeng ^a   Ma, Xiangyi ^a   Yang, Wanhua ^a   Xi, Yandong ^a   Wang, Hongyan ^a   Qian, Ming ^a   Fan, Liangsheng ^a   Xia, Xi ^a,b   Li, Kezheng ^a   Wang, Daowen ^a   Zhou, Jianfeng ^a   Meng, Li ^a   Wang, Shixuan ^a   Ma, Ding ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b The 6th Affiliated Hospital of Shenzhen University Health Science Center   (China)

Author keywords

Metastasis; NF B; Peptide; Targeting; TMTP1

Indexed keywords

ANTI-TUMOR AGENTS; ANTICANCER EFFECTS; ANTITUMOR EFFECT; IN-VITRO; IN-VIVO; METASTASIS; MICE MODELS; NEGATIVE CHARGE; SIGNALING PATHWAYS; TARGETING; TMTP1; TUMOR CELLS; TUMOR DEVELOPMENT; TUMOR METASTASIS;

CELL DEATH; FLUORESCENCE; PATHOLOGY; PEPTIDES;

TUMORS;

ANTIMETASTATIC AGENT; ANTINEOPLASTIC AGENT; BETA ACTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3BETA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEPTIDE DERIVATIVE; PROTEIN KINASE B; PROTEIN TMTP1; SVTMTP1 TAT NBD FUSION PEPTIDE; SYNAPTOTAGMIN I; TAT NBD FUSION PEPTIDE; TMTP1 NBD FUSION PEPTIDE; TMTP1 TAT NBD FUSION PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BIOACCUMULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DOSE TIME EFFECT RELATION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG SAFETY; DRUG SELECTIVITY; DRUG TARGETING; DRUG TUMOR LEVEL; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIVER METASTASIS; LYMPH NODE METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR CELL; TUMOR MODEL;

3T3 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; NEOPLASMS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84864587031     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.05.002     Document Type: Article

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