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Volumn 23, Issue 5, 2009, Pages 1396-1404

Novel peptide ligand directs liposomes toward EGF-R high-expressing cancer cells in vitro and in vivo

Author keywords

AutoDock; Computer aided design; Epidermal growth factor; Lipid; PEG; Proteomic code

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; LEUCYLALANYLARGINYLLEUCYLLEUCYLTHREONINE; LIPOSOME; MACROGOL; PEPTIDE; PEPTIDE LIBRARY; UNCLASSIFIED DRUG;

EID: 69949164681     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-117002     Document Type: Article
Times cited : (129)

References (47)
  • 1
    • 0028349925 scopus 로고
    • Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
    • Gabizon, A., Catane, R., Uziely, B., Kaufman, B., Safra, T., Cohen, R., Martin, F., Huang, A., and Barenholz, Y. (1994) Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 54, 987-992 (Pubitemid 24085451)
    • (1994) Cancer Research , vol.54 , Issue.4 , pp. 987-992
    • Gabizon, A.1    Catane, R.2    Uziely, B.3    Kaufman, B.4    Safra, T.5    Cohen, R.6    Martin, F.7    Huang, A.8    Barenholz, Y.9
  • 2
    • 0028953974 scopus 로고
    • Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal antibodies
    • Maruyama, K., Takizawa, T., Yuda, T., Kennel, S. J., Huang, L., and Iwatsuru, M. (1995) Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal antibodies. Biochim. Biophys. Acta 1234, 74-80
    • (1995) Biochim. Biophys. Acta , vol.1234 , pp. 74-80
    • Maruyama, K.1    Takizawa, T.2    Yuda, T.3    Kennel, S.J.4    Huang, L.5    Iwatsuru, M.6
  • 4
    • 0029828939 scopus 로고    scopus 로고
    • Targeting of stealth liposomes to erbB-2 (Her/2) receptor: In vitro and in vivo studies
    • Goren, D., Horowitz, A. T., Zalipsky, S., Woodle, M. C., Yarden, Y., and Gabizon, A. (1996) Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies. Br. J. Cancer 74, 1749-1756 (Pubitemid 26401894)
    • (1996) British Journal of Cancer , vol.74 , Issue.11 , pp. 1749-1756
    • Goren, D.1    Horowitz, A.T.2    Zalipsky, S.3    Woodle, M.C.4    Yarden, Y.5    Gabizon, A.6
  • 5
    • 0001160175 scopus 로고    scopus 로고
    • In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
    • Lopes de Menezes, D. E., Pilarski, L. M., and Allen, T. M. (1998) In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 58, 3320-3330
    • (1998) Cancer Res. , vol.58 , pp. 3320-3330
    • Lopes De Menezes, D.E.1    Pilarski, L.M.2    Allen, T.M.3
  • 7
    • 0028794831 scopus 로고
    • Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro
    • Lee, R. J., and Low, P. S. (1995) Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochim. Biophys. Acta 1233, 134-144
    • (1995) Biochim. Biophys. Acta , vol.1233 , pp. 134-144
    • Lee, R.J.1    Low, P.S.2
  • 8
    • 0346333236 scopus 로고    scopus 로고
    • In Vivo Fate of Folate-Targeted Polyethylene-Glycol Liposomes in Tumor-Bearing Mice
    • Gabizon, A., Horowitz, A. T., Goren, D., Tzemach, D., Shmeeda, H., and Zalipsky, S. (2003) In vivo fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing mice. Clin. Cancer Res. 9, 6551-6559 (Pubitemid 38031844)
    • (2003) Clinical Cancer Research , vol.9 , Issue.17 , pp. 6551-6559
    • Gabizon, A.1    Horowitz, A.T.2    Goren, D.3    Tzemach, D.4    Shmeeda, H.5    Zalipsky, S.6
  • 9
    • 33750096959 scopus 로고    scopus 로고
    • Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells
    • DOI 10.1080/10611860600849498, PII N483U410U47W9625
    • Terada, T., Mizobata, M., Kawakami, S., Yabe, Y., Yamashita, F., and Hashida, M. (2006) Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. J. Drug Target. 14, 536-545 (Pubitemid 44592887)
    • (2006) Journal of Drug Targeting , vol.14 , Issue.8 , pp. 536-545
    • Terada, T.1    Mizobata, M.2    Kawakami, S.3    Yabe, Y.4    Yamashita, F.5    Hashida, M.6
  • 11
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon, D. S., Brandt, R., Ciardiello, F., and Normanno, N. (1995) Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 19, 183-232
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 12
    • 0036875515 scopus 로고    scopus 로고
    • Cytotoxic and antitumor activities of doxorubicin conjugates with the epidermal growth factor and its receptor-binding fragment
    • Lutsenko, S. V., Feldman, N. B., and Severin, S. E. (2002) Cytotoxic and antitumor activities of doxorubicin conjugates with the epidermal growth factor and its receptor-binding fragment. J. Drug Target. 10, 567-571
    • (2002) J. Drug Target. , vol.10 , pp. 567-571
    • Lutsenko, S.V.1    Feldman, N.B.2    Severin, S.E.3
  • 13
    • 0029679627 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-dependent cytotoxic effect by an EGF-ribonuclease conjugate on human cancer cell lines: A trial for less immunogenic chimeric toxin
    • DOI 10.1007/s002800050487
    • Jinno, H., Ueda, M., Ozawa, S., Kikuchi, K., Ikeda, T., Enomoto, K., and Kitajima, M. (1996) Epidermal growth factor receptor-dependent cytotoxic effect by an EGF-ribonuclease conjugate on human cancer cell lines: a trial for less immunogenic chimeric toxin. Cancer Chemother. Pharmacol. 38, 303-308 (Pubitemid 26226295)
    • (1996) Cancer Chemotherapy and Pharmacology , vol.38 , Issue.4 , pp. 303-308
    • Jinno, H.1    Ueda, M.2    Ozawa, S.3    Kikuchi, K.4    Ikeda, T.5    Enomoto, K.6    Kitajima, M.7
  • 14
    • 0037331306 scopus 로고    scopus 로고
    • Tumor-cell targeted epidermal growth factor liposomes loaded with boronated acridine: Uptake and processing
    • DOI 10.1023/A:1022223204460
    • Kullberg, E. B., Nestor, M., and Gedda, L. (2003) Tumor-cell targeted epiderimal growth factor liposomes loaded with boronated acridine: uptake and processing. Pharm. Res. 20, 229-236 (Pubitemid 36269729)
    • (2003) Pharmaceutical Research , vol.20 , Issue.2 , pp. 229-236
    • Kullberg, E.B.1    Nestor, M.2    Gedda, L.3
  • 15
    • 0036701613 scopus 로고    scopus 로고
    • 111In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells
    • DOI 10.1016/S0969-8051(02)00325-6, PII S0969805102003256
    • Chen, P., Mrkobrada, M., Vallis, K. A., Cameron, R., Sandhu, J., Hendler, A., and Reilly, R. M. (2002) Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells. Nucl. Med. Biol. 29, 693-699 (Pubitemid 35266670)
    • (2002) Nuclear Medicine and Biology , vol.29 , Issue.6 , pp. 693-699
    • Chen, P.1    Mrkobrada, M.2    Vallis, K.A.3    Cameron, R.4    Sandhu, J.5    Hendler, A.6    Reilly, R.M.7
  • 16
    • 0034924636 scopus 로고    scopus 로고
    • Different strategies for formation of PEGylated EGF-conjugated PEI/DNA complexes for targeted gene delivery
    • DOI 10.1021/bc0001488
    • Blessing, T., Kursa, M., Holzhauser, R., Kircheis, R., and Wagner, E. (2001) Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery. Bioconjug. Chem. 12, 529-537 (Pubitemid 32696226)
    • (2001) Bioconjugate Chemistry , vol.12 , Issue.4 , pp. 529-537
    • Blessing, T.1    Kursa, M.2    Holzhauser, R.3    Kircheis, R.4    Wagner, E.5
  • 17
    • 0037731636 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- And EGFRvIII-overexpressing tumor cells
    • Mamot, C., Drummond, D. C., Greiser, U., Hong, K., Kirpotin, D. B., Marks, J. D., and Park, J. W. (2003) Epidermal growth factor receptor (EGFR) -targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res. 63, 3154-3161 (Pubitemid 36735867)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3154-3161
    • Mamot, C.1    Drummond, D.C.2    Greiser, U.3    Hong, K.4    Kirpotin, D.B.5    Marks, J.D.6    Park, J.W.7
  • 18
    • 29244489232 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo
    • DOI 10.1158/0008-5472.CAN-05-1093
    • Mamot, C., Drummond, D. C., Noble, C. O., Kallab, V., Guo, Z., Hong, K., Kirpotin, D. B., and Park, J. W. (2005) Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo. Cancer Res. 65, 11631-11638 (Pubitemid 41821723)
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11631-11638
    • Mamot, C.1    Drummond, D.C.2    Noble, C.O.3    Kallab, V.4    Guo, Z.5    Hong, K.6    Kirpotin, D.B.7    Park, J.W.8
  • 19
    • 33745284972 scopus 로고    scopus 로고
    • EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells
    • DOI 10.1080/10611860600691049, PII VX303602110285
    • Mamot, C., Ritschard, R., Kung, W., Park, J. W., Herrmann, R., and Rochlitz, C. F. (2006) EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells. J. Drug Target. 14, 215-223 (Pubitemid 43922062)
    • (2006) Journal of Drug Targeting , vol.14 , Issue.4 , pp. 215-223
    • Mamot, C.1    Ritschard, R.2    Kung, W.3    Park, J.W.4    Herrmann, R.5    Rochlitz, C.F.6
  • 20
    • 0036523474 scopus 로고    scopus 로고
    • Specific interactions between sense and complementary peptides: The basis for the proteomic code
    • DOI 10.1002/1439-7633(20020301)3:2/3<136::AID-CBIC136>3.0.CO;2-7
    • Heal, J. R., Roberts, G. W., Raynes, J. G., Bhakoo, A., and Miller, A. D. (2002) Specific interactions between sense and complementary peptides: the basis for the proteomic code. ChemBioChem 3, 136-151 (Pubitemid 36004488)
    • (2002) ChemBioChem , vol.3 , Issue.2-3 , pp. 136-151
    • Heal, J.R.1    Roberts, G.W.2    Raynes, J.G.3    Bhakoo, A.4    Miller, A.D.5
  • 21
    • 0032858556 scopus 로고    scopus 로고
    • A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs
    • DOI 10.1016/S0014-5793(99)01320-4, PII S0014579399013204
    • Ishida, T., Iden, D. L., and Allen, T. M. (1999) A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs. FEBS Lett. 460, 129-133 (Pubitemid 29479257)
    • (1999) FEBS Letters , vol.460 , Issue.1 , pp. 129-133
    • Ishida, T.1    Iden, D.L.2    Allen, T.M.3
  • 22
    • 0025346245 scopus 로고
    • Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients
    • Mayer, L. D., Tai, L. C., Bally, M. B., Mitilenes, G. N., Ginsberg, R. S., and Cullis, P. R. (1990) Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients. Biochim. Biophys. Acta 1025, 143-151
    • (1990) Biochim. Biophys. Acta , vol.1025 , pp. 143-151
    • Mayer, L.D.1    Tai, L.C.2    Bally, M.B.3    Mitilenes, G.N.4    Ginsberg, R.S.5    Cullis, P.R.6
  • 23
    • 23444437683 scopus 로고
    • Erratum: Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases (Biochim. Biophys. Acta 1151 (1993) 201-215 (BBAMEM 76069))
    • DOI 10.1016/0005-2736(94)90054-X
    • Haran, G., Cohen, R., Bar, L. K., and Barenholz, Y. (1994) Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta (1993) 1151, 201-215; erratum in Biochim. Biophys. Acta 1190, 197 (Pubitemid 24066280)
    • (1994) Biochimica et Biophysica Acta - Biomembranes , vol.1190 , Issue.1 , pp. 197
    • Haran, G.1    Cohen, R.2    Bar, L.K.3    Barenholz, Y.4
  • 25
    • 0036084259 scopus 로고    scopus 로고
    • Efficient docking of peptides to proteins without prior knowledge of the binding site
    • DOI 10.1110/ps.0202302
    • Hetenyi, C., and van der Spoel, D. (2002) Efficient docking of peptides to proteins without prior knowledge of the binding site. Protein Sci. 11, 1729-1737 (Pubitemid 34663553)
    • (2002) Protein Science , vol.11 , Issue.7 , pp. 1729-1737
    • Hetenyi, C.1    Van Der Spoel, D.2
  • 27
    • 1642498316 scopus 로고    scopus 로고
    • HER1/EGFR targeting: Refining the strategy
    • Pérez-Soler, R. (2004) HER1/EGFR targeting: refining the strategy. Oncologist 9, 58-67
    • (2004) Oncologist , vol.9 , pp. 58-67
    • Pérez-Soler, R.1
  • 28
    • 0031011597 scopus 로고    scopus 로고
    • Construction and functional characterization of scFv(14E1)-ETA - A novel, highly potent antibody-toxin specific for the EGF receptor
    • Schmidt, M., Vakalopoulou, E., Schneider, D. W., and Wels, W. (1997) Construction and functional characterization of scFv(14E1)-ETA: a novel, highly potent antibody-toxin specific for the EGF receptor. Br. J. Cancer 75, 1575-1584 (Pubitemid 27229046)
    • (1997) British Journal of Cancer , vol.75 , Issue.11 , pp. 1575-1584
    • Schmidt, M.1    Vakalopoulou, E.2    Schneider, D.W.3    Wels, W.4
  • 29
    • 85047699262 scopus 로고    scopus 로고
    • WAF-1 and GM-CSF gene transfer in the established murine hepatoma by peritumoral injection
    • DOI 10.1038/sj/cgt/7700400
    • Liu, X., Tian, P., Yu, Y., Yao, M., Cao, X., and Gu, J. (2002) Enhanced antitumor effect of EGFR-targeted p21WAF-1 and GM-CSF gene transfer in the established murine hepatoma by peritumoral injection. Cancer Gene Ther. 9, 100-108 (Pubitemid 34052859)
    • (2002) Cancer Gene Therapy , vol.9 , Issue.1 , pp. 100-108
    • Liu, X.1    Tian, P.2    Yu, Y.3    Yao, M.4    Cao, X.5    Gu, J.6
  • 30
    • 28744436511 scopus 로고    scopus 로고
    • Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics
    • DOI 10.1096/fj.05-4058com
    • Li, Z., Zhao, R., Wu, X., Sun, Y., Yao, M., Li, J., Xu, Y., and Gu, J. (2005) Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics. FASEB J. 19, 1978-1985 (Pubitemid 41759743)
    • (2005) FASEB Journal , vol.19 , Issue.14 , pp. 1978-1985
    • Li, Z.1    Zhao, R.2    Wu, X.3    Sun, Y.4    Yao, M.5    Li, J.6    Xu, Y.7    Gu, J.8
  • 31
    • 17144368025 scopus 로고    scopus 로고
    • Binding mode prediction of cytochrome P450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking
    • DOI 10.1021/jm049650u
    • De Graaf, C., Pospisil, P., Pos, W., Folkers, G., and Vermeulen, N. P. (2005) Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking. J. Med. Chem. 48, 2308-2318 (Pubitemid 40516425)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.7 , pp. 2308-2318
    • De Graaf, C.1    Pospisil, P.2    Pos, W.3    Folkers, G.4    Vermeulen, N.P.E.5
  • 33
    • 5144228627 scopus 로고    scopus 로고
    • De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18)
    • DOI 10.1016/j.molimm.2004.05.011, PII S0161589004002238
    • Bhakoo, A., Raynes, J. G., Heal, J. R., Keller, M., and Miller, A. D. (2004) De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18). Mol. Immunol. 41, 1217-1224 (Pubitemid 39346269)
    • (2004) Molecular Immunology , vol.41 , Issue.12 , pp. 1217-1224
    • Bhakoo, A.1    Raynes, J.G.2    Heal, J.R.3    Keller, M.4    Miller, A.D.5
  • 34
    • 34247535100 scopus 로고    scopus 로고
    • Sensitivity characterization of a time-domain fluorescence imager: EXplore Optix
    • DOI 10.1364/AO.46.001650
    • Ma, G., Gallant, P., and McIntosh, L. (2007) Sensitivity characterization of a time-domain fluorescence imager: eXplore Optix. Appl. Opt. 46, 1650-1657 (Pubitemid 46659531)
    • (2007) Applied Optics , vol.46 , Issue.10 , pp. 1650-1657
    • Ma, G.1    Gallant, P.2    McIntosh, L.3
  • 35
    • 33750971995 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model
    • Hsu, A. R., Hou, L. C., Veeravagu, A., Greve, J. M., Vogel, H., Tse, V., and Chen, X. (2006) In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model. Mol. Imaging Biol. 8, 315-323
    • (2006) Mol. Imaging Biol. , vol.8 , pp. 315-323
    • Hsu, A.R.1    Hou, L.C.2    Veeravagu, A.3    Greve, J.M.4    Vogel, H.5    Tse, V.6    Chen, X.7
  • 36
    • 0344844469 scopus 로고    scopus 로고
    • Near-Infrared Optical Imaging of Epidermal Growth Factor Receptor in Breast Cancer Xenografts
    • Ke, S., Wen, X., Gurfinkel, M., Charnsangavej, C., Wallace, S., Sevick-Muraca, E. M., and Li, C. (2003) Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenografts. Cancer Res. 63, 7870-7875 (Pubitemid 37466721)
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7870-7875
    • Ke, S.1    Wen, X.2    Gurfinkel, M.3    Charnsangavej, C.4    Wallace, S.5    Sevick-Muraca, E.M.6    Li, C.7
  • 37
    • 0032851735 scopus 로고    scopus 로고
    • Immunoliposomes for the targeted delivery of antitumor drugs
    • DOI 10.1016/S0169-409X(99)00043-5, PII S0169409X99000435
    • Mastrobattista, E., Koning, G. A., and Storm, G. (1999) Immunoliposomes for the targeted delivery of antitumor drugs. Adv. Drug Delivery Rev. 40, 103-127 (Pubitemid 29486607)
    • (1999) Advanced Drug Delivery Reviews , vol.40 , Issue.1-2 , pp. 103-127
    • Mastrobattista, E.1    Koning, G.A.2    Storm, G.3
  • 38
    • 33748498232 scopus 로고    scopus 로고
    • Pros and cons of the liposome platform in cancer drug targeting
    • DOI 10.1080/08982100600848769, PII L240472212U58PQ4
    • Gabizon, A. A., Shmeeda, H., and Zalipsky, S. (2006) Pros and cons of the liposome platform in cancer drug targeting. J. Liposome Res. 16, 175-183 (Pubitemid 44358991)
    • (2006) Journal of Liposome Research , vol.16 , Issue.3 , pp. 175-183
    • Gabizon, A.A.1    Shmeeda, H.2    Zalipsky, S.3
  • 39
    • 0034848288 scopus 로고    scopus 로고
    • Pharmacokinetics of differently designed immunoliposome formulations in rats with or without hepatic colon cancer metastases
    • DOI 10.1023/A:1013085811044
    • Koning, G. A., Morselt, H. W., Gorter, A., Allen, T. M., Zalipsky, S., Kamps, J. A., and Scherphof, G. L. (2001) Pharmacokinetics of differently designed immunoliposome formulations in rats with or without hepatic colon cancer metastases. Pharm. Res. 18, 1291-1298 (Pubitemid 32846322)
    • (2001) Pharmaceutical Research , vol.18 , Issue.9 , pp. 1291-1298
    • Koning, G.A.1    Morselt, H.W.M.2    Gorter, A.3    Allen, T.M.4    Zalipsky, S.5    Kamps, J.A.A.M.6    Scherphof, G.L.7
  • 40
    • 0042626531 scopus 로고    scopus 로고
    • Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison
    • DOI 10.1023/A:1025009300562
    • Koning, G. A., Morselt, H. W., Gorter, A., Allen, T. M., Zalipsky, S., Scherphof, G. L., and Kamps, J. A. (2003) Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells: an in vitro comparison. Pharm. Res. 20, 1249-1257 (Pubitemid 36951850)
    • (2003) Pharmaceutical Research , vol.20 , Issue.8 , pp. 1249-1257
    • Koning, G.A.1    Morselt, H.W.M.2    Gorter, A.3    Allen, T.M.4    Zalipsky, S.5    Scherphof, G.L.6    Kamps, J.A.A.M.7
  • 41
    • 0023764933 scopus 로고
    • Uptake and processing of immunoglobulin-coated liposomes by subpopulations of rat liver macrophages
    • DOI 10.1016/0167-4889(88)90184-X
    • Derksen, J. T., Morselt, H. W., and Scherphof, G. L. (1988) Uptake and processing of immunoglobulin-coated liposomes by subpopulations of rat liver macrophages. Biochim. Biophys. Acta 971, 127-136 (Pubitemid 18228064)
    • (1988) Biochimica et Biophysica Acta - Molecular Cell Research , vol.971 , Issue.2 , pp. 127-136
    • Derksen, J.T.P.1    Morselt, H.W.M.2    Scherphof, G.L.3
  • 42
    • 0030876540 scopus 로고    scopus 로고
    • Immunoliposomes bearing polyethyleneglycol-coupled Fab' fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo
    • DOI 10.1016/S0014-5793(97)00905-8, PII S0014579397009058
    • Maruyama, K., Takahashi, N., Tagawa, T., Nagaike, K., and Iwatsuru, M. (1997) Immunoliposomes bearing poloethylene glycol-coupled Fab′ fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo. FEBS Lett. 413, 177-180 (Pubitemid 27348659)
    • (1997) FEBS Letters , vol.413 , Issue.1 , pp. 177-180
    • Maruyama, K.1    Takahashi, N.2    Tagawa, T.3    Nagaike, K.4    Iwatsuru, M.5
  • 43
    • 0030987679 scopus 로고    scopus 로고
    • Receptor mediated delivery of daunomycin using immunoliposomes: Pharmacokinetics and tissue distribution in the rat
    • Huwyler, J., Yang, J., and Pardridge, W. M. (1997) Receptor mediated delivery of daunomycin using immunoliposomes: pharmacokinetics and tissue distribution in the rat. J. Pharmacol. Exp. Ther. 282, 1541-1546 (Pubitemid 27408339)
    • (1997) Journal of Pharmacology and Experimental Therapeutics , vol.282 , Issue.3 , pp. 1541-1546
    • Huwyler, J.1    Yang, J.2    Pardridge, W.M.3
  • 45
    • 33746172167 scopus 로고    scopus 로고
    • Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
    • DOI 10.1158/0008-5472.CAN-05-4199
    • Kirpotin, D. B., Drummond, D. C., Shao, Y., Shalaby, M. R., Hong, K., Nielsen, U. B., Marks, J. D., Benz, C. C., and Park, J. W. (2006) Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res. 66, 6732-6740 (Pubitemid 44085631)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6732-6740
    • Kirpotin, D.B.1    Drummond, D.C.2    Shao, Y.3    Shalaby, M.R.4    Hong, K.5    Nielsen, U.B.6    Marks, J.D.7    Benz, C.C.8    Park, J.W.9
  • 46
    • 1042290308 scopus 로고    scopus 로고
    • Improved Therapeutic Responses in a Xenograft Model of Human B Lymphoma (Namalwa) for Liposomal Vincristine versus Liposomal Doxorubicin Targeted via Anti-CD19 IgG2a or Fab′ Fragments
    • DOI 10.1158/1078-0432.CCR-03-0041
    • Sapra, P., Moase, E. H., Ma, J., and Allen, T. M. (2004) Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab′ fragments. Clin. Cancer Res. 10, 1100-1111 (Pubitemid 38198912)
    • (2004) Clinical Cancer Research , vol.10 , Issue.3 , pp. 1100-1111
    • Sapra, P.1    Moase, E.H.2    Ma, J.3    Allen, T.M.4
  • 47
    • 51649093438 scopus 로고    scopus 로고
    • Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo
    • Song, S., Liu, D., Peng, J., Sun, Y., Li, Z., Gu, J. R., and Xu, Y. (2008) Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo. Int. J. Pharm. 363, 155-161
    • (2008) Int. J. Pharm. , vol.363 , pp. 155-161
    • Song, S.1    Liu, D.2    Peng, J.3    Sun, Y.4    Li, Z.5    Gu, J.R.6    Xu, Y.7


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