Testing for antibodies to human aquaporin-4 by ELISA: Sensitivity, specificity, and direct comparison with immunohistochemistry

Journal of the Neurological Sciences

Volumn 320, Issue 1-2, 2012, Pages 32-37

  Jarius, S ^a   Franciotta, D ^b   Paul, F ^c   Bergamaschi, R ^b   Rommer, P S ^d   Ruprecht, K ^c   Ringelstein, M ^e   Aktas, O ^e   Kristoferitsch, W ^f   Wildemann, B ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e HEINRICH HEINE UNIVERSITY   (Germany)

^f Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders   (Austria)

Author keywords

Antibody to aquaporin 4; Diagnosis; Enzyme linked immunosorbent assay (ELISA); Indirect immunofluorescence; Longitudinally extensive transverse myelitis; Multiple sclerosis; Neuromyelitis optica (Devic's syndrome); NMO IgG; Optic neuritis; Recombinant antigen

Indexed keywords

AQUAPORIN 4 ANTIBODY; IMMUNOGLOBULIN G;

ADOLESCENT; ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LONGITUDINALLY EXTENSIVE MYELITIS; MAJOR CLINICAL STUDY; MALE; MYELITIS; MYELOOPTIC NEUROPATHY; OPTIC NEURITIS; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; AQUAPORIN 4; AUTOANTIBODIES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MIDDLE AGED; MYELITIS, TRANSVERSE; NEUROMYELITIS OPTICA; OPTIC NEURITIS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84864586006     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.06.002     Document Type: Article

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