Antibodies to CV2/CRMP5 in neuromyelitis optica-like disease: Case report and review of the literature

Clinical Neurology and Neurosurgery

Volumn 114, Issue 4, 2012, Pages 331-335

  Jarius, S ^a   Wandinger, K P ^b,c   Borowski, K ^c   Stoecker, W ^c   Wildemann, B ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Institute of Experimental Immunology   (Germany)

Author keywords

Aquaporin 4 antibody; CRMP5 antibody; CV2 antibody; Longitudinally extensive transverse myelitis; Neuromyelitis optica (Devic syndrome); NMO IgG; Optic neuritis; Paraneoplastic neurological disorders; Prostate cancer

Indexed keywords

ANTIBODY; AQUAPORIN 4; AZATHIOPRINE; CRMP5 ANTIBODY; CV2 ANTIBODY; METHYLPREDNISOLONE; UNCLASSIFIED DRUG;

AGED; BRAIN TISSUE; CASE REPORT; DIAGNOSTIC TEST; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; HUMAN; IMMUNOFLUORESCENCE; IMMUNOPATHOGENESIS; MALE; MYELOOPTIC NEUROPATHY; PARANEOPLASTIC SYNDROME; PROSTATE CANCER; REVIEW; SENSITIVITY AND SPECIFICITY;

EID: 84859422959     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2011.10.048     Document Type: Article

References (32)

1. D.M. Wingerchuk, W.F. Hogancamp, P.C. O'Brien, and B.G. Weinshenker The clinical course of neuromyelitis optica (Devic's syndrome) Neurology 53 1999 1107 1114 (Pubitemid 29442132)
2. S. Jarius, D. Franciotta, R. Bergamaschi, H. Wright, E. Littleton, and J. Palace NMO-IgG in the diagnosis of neuromyelitis optica Neurology 68 2007 1076 1077 (Pubitemid 46569147)
3. V.A. Lennon, D.M. Wingerchuk, T.J. Kryzer, S.J. Pittock, C.F. Lucchinetti, and K. Fujihara A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis Lancet 364 2004 2106 2112 (Pubitemid 39626806)
4. F. Paul, S. Jarius, O. Aktas, M. Bluthner, O. Bauer, and H. Appelhans Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica PLoS Med 4 2007 e133
5. V.A. Lennon, T.J. Kryzer, S.J. Pittock, A.S. Verkman, and S.R. Hinson IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel J Exp Med 202 2005 473 477 (Pubitemid 41186945)
6. P. Waters, S. Jarius, E. Littleton, M.I. Leite, S. Jacob, and B. Gray Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis Arch Neurol 65 2008 913 919 (Pubitemid 352008474)
7. S. Jarius, F. Paul, D. Franciotta, P. Waters, F. Zipp, and R. Hohlfeld Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica Nat Clin Pract Neurol 4 2008 202 214 (Pubitemid 351516748)
8. S. Jarius, and B. Wildemann AQP4 antibodies in neuromyelitis optica: pathogenic and diagnostic relevance Nat Rev Neurol 6 2010 383 392
9. M. Bonnan, R. Valentino, S. Olindo, H. Mehdaoui, D. Smadja, and P. Cabre Plasma exchange in severe spinal attacks associated with neuromyelitis optica spectrum disorder Mult Scler 15 2009 487 492
10. S. Jarius, C. Probst, K. Borowski, D. Franciotta, B. Wildemann, and W. Stoecker Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen J Neurol Sci 291 2010 52 56
11. S.J. Pittock, V.A. Lennon, J. de Seze, P. Vermersch, H.A. Homburger, and D.M. Wingerchuk Neuromyelitis optica and non organ-specific autoimmunity Arch Neurol 65 2008 78 83
12. J. Sellner, B. Hemmer, and M. Muhlau The clinical spectrum and immunobiology of parainfectious neuromyelitis optica (Devic) syndromes J Autoimmun 34 2010 371 379
13. S.J. Pittock, and V.A. Lennon Aquaporin-4 autoantibodies in a paraneoplastic context Arch Neurol 65 2008 629 632 (Pubitemid 351679657)
14. T. Takahashi, K. Fujihara, I. Nakashima, T. Misu, I. Miyazawa, and M. Nakamura Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre Brain 130 2007 1235 1243 (Pubitemid 47355956)
15. J. Honnorat, J.C. Antoine, E. Derrington, M. Aguera, and M.F. Belin Antibodies to a subpopulation of glial cells and a 66 kDa developmental protein in patients with paraneoplastic neurological syndromes J Neurol Neurosurg Psychiatry 61 1996 270 278 (Pubitemid 26293722)
16. Z. Yu, T.J. Kryzer, G.E. Griesmann, K. Kim, E.E. Benarroch, and V.A. Lennon CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity Ann Neurol 49 2001 146 154 (Pubitemid 32157990)
17. J. Honnorat, S. Cartalat-Carel, D. Ricard, J.P. Camdessanche, A.F. Carpentier, and V. Rogemond Onco-neural antibodies and tumour type determine survival and neurological symptoms in paraneoplastic neurological syndromes with Hu or CV2/CRMP5 antibodies J Neurol Neurosurg Psychiatry 80 2009 412 416
18. P.A. Abrahamsson Neuroendocrine differentiation in prostatic carcinoma Prostate 39 1999 135 148
19. T. Ritzenthaler, J.M. Verret, and J. Honnorat Paraneoplastic chorea and behavioral disorders in a patient with anti-CV2/CRMP5 antibodies and two different tumors Rev Neurol (Paris) 166 2010 90 95
20. S.A. Cross, D.R. Salomao, J.E. Parisi, T.J. Kryzer, E.A. Bradley, and J.A. Mines Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG Ann Neurol 54 2003 38 50 (Pubitemid 36764980)
21. F. Ducray, R. Roos-Weil, P.Y. Garcia, J. Slesari, O. Heinzlef, and D. Chatelain Devic's syndrome-like phenotype associated with thymoma and anti-CV2/CRMP5 antibodies J Neurol Neurosurg Psychiatry 78 2007 325 327 (Pubitemid 46579678)
22. B.M. Keegan, S.J. Pittock, and V.A. Lennon Autoimmune myelopathy associated with collapsin response-mediator protein-5 immunoglobulin G Ann Neurol 63 2008 531 534 (Pubitemid 351614719)
23. D.M. Wingerchuk, V.A. Lennon, S.J. Pittock, C.F. Lucchinetti, and B.G. Weinshenker Revised diagnostic criteria for neuromyelitis optica Neurology 66 2006 1485 1489 (Pubitemid 43958540)
24. S. Jarius, S. Arnold, R. Linke, S. Noachtar, M. Schlemmer, and R. Issels Long term survival in anti-Hu associated adult neuroblastoma J Neurol Sci 284 2009 205 208
25. F. Graus, J. Dalmou, R. Rene, M. Tora, N. Malats, and J.J. Verschuuren Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival J Clin Oncol 15 1997 2866 2872 (Pubitemid 27330014)
26. A. Poepel, S. Jarius, L.C. Heukamp, H. Urbach, C.E. Elger, and C.G. Bien Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome J Neurol Sci 263 2007 145 148 (Pubitemid 350029856)
27. G. De Santis, L. Caniatti, A. De Vito, R. De Gennaro, E. Granieri, and M.R. Tola A possible paraneoplastic neuromyelitis optica associated with lung cancer Neurol Sci 30 2009 397 400
28. S. Mueller, D.B. Dubal, and S.A. Josephson A case of paraneoplastic myelopathy associated with the neuromyelitis optica antibody Nat Clin Pract Neurol 4 2008 284 288 (Pubitemid 351639549)
29. S. Jarius, A. Warth, K.P. Wandinger, P.A. Schnabel, H. Hoffmann, and B. Wildemann Antibodies to aquaporin-4 in non-small cell lung cancer: a study on 50 patients Neurol Sci 31 2010 871 872
30. F. Graus, F. Keime-Guibert, R. Rene, B. Benyahia, T. Ribalta, and C. Ascaso Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients Brain 124 2001 1138 1148 (Pubitemid 32510382)
31. S. Jarius, C. Jacobi, J. de Seze, H. Zephir, F. Paul, and D. Franciotta Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders Mult Scler 17 2011 1067 1073
32. S. Jarius, F. Paul, D. Franciotta, J. de Seze, C. Munch, and M. Salvetti Neuromyelitis optica in patients with juvenile or early onset myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature Mult Scler 2011 10.1177/1352458511431728