Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity

PLoS Pathogens

Volumn 8, Issue 7, 2012, Pages 7-

  Ejigiri, Ijeoma ^a   Ragheb, Daniel R T ^b   Pino, Paco ^c   Coppi, Alida ^a   Bennett, Brandy Lee ^a   Soldati Favre, Dominique ^c   Sinnis, Photini ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; CELL RECEPTOR; LEUPEPTIN; MEMBRANE PROTEIN; PEPSTATIN; PROTEINASE; PROTEINASE INHIBITOR; RHOMBOID PROTEASE; TRAP PROTEIN; UNCLASSIFIED DRUG; PEPTIDE HYDROLASE; PROTOZOAL PROTEIN; THROMBOSPONDIN RELATED ADHESIVE PROTEIN, PROTOZOAN; THROMBOSPONDIN-RELATED ADHESIVE PROTEIN, PROTOZOAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL INVASION; CELL MOTILITY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HOST CELL; HYPOTHESIS; INOCULATION; MALARIA; MOUSE; MUTANT; NONHUMAN; PHENOTYPE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; SPOROZOITE; ANIMAL; ANOPHELES; C57BL MOUSE; CELL MOTION; GENETICS; METABOLISM; MUTATION; PARASITOLOGY; PATHOGENICITY; PHYSIOLOGY; PLASMODIUM BERGHEI;

ANIMALS; ANOPHELES; CELL MOVEMENT; EXTRACELLULAR MATRIX; MALARIA; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MUTATION; PEPTIDE HYDROLASES; PLASMODIUM BERGHEI; PROTOZOAN PROTEINS; SPOROZOITES;

EID: 84864576516     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002725     Document Type: Article

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